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Kay, Alexander W, González Fernández, Lucia, Takwoingi, Yemisi, Eisenhut, Michael, Vu, Ryan D, Steingart, Karen, Detjen, Anne K and Mandalakas, Anna M (2019) 'Xpert MTB/RIF and Xpert MTB/RIF Ultra assays for active tuberculosis and rifampicin resistance in children'. Cochrane Database of Systematic Reviews, Vol 6, CD013359.
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Abstract
This is a protocol for a Cochrane Review (Diagnostic test accuracy). The objectives are as follows:
Primary objectives
To determine the diagnostic accuracy of Xpert MTB/RIF and Xpert Ultra for a) PTB in children presumed to have tuberculosis; b) lymph node tuberculosis in children presumed to have tuberculosis; c) tuberculous meningitis in children presumed to have tuberculosis; and d) rifampicin resistance in children presumed to have tuberculosis.
For tuberculosis detection, the role of the index tests would be a replacement for standard practice.
For rifampicin resistance detection, the role of the index tests would be an initial replacement test for culture‐based drug susceptibility testing.
| Item Type: | Article |
|---|---|
| Subjects: | WF Respiratory System > Tuberculosis > WF 200 Tuberculosis (General) WF Respiratory System > Tuberculosis > WF 310 Therapy WF Respiratory System > Lungs > WF 600 Lungs WS Pediatrics > WS 100 General works |
| Faculty: Department: | Clinical Sciences & International Health > Clinical Sciences Department |
| Digital Object Identifer (DOI): | https://doi.org/10.1002/14651858.CD013359 |
| SWORD Depositor: | JISC Pubrouter |
| Depositing User: | Stacy Murtagh |
| Date Deposited: | 01 Jul 2019 12:59 |
| Last Modified: | 17 Jun 2020 01:02 |
| URI: | https://archive.lstmed.ac.uk/id/eprint/11094 |
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