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Bleach-digested sputum smears for the diagnosis of TB in HIV-infected individuals

Douthwaite, S., Yassin, Mohammed A., Squire, Bertie ORCID: https://orcid.org/0000-0001-7173-9038, Arbide, I. and Cuevas, Luis ORCID: https://orcid.org/0000-0002-6581-0587 (2007) 'Bleach-digested sputum smears for the diagnosis of TB in HIV-infected individuals'. Tropical Doctor, Vol 37, Issue 1, pp. 35-36.

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Abstract

We describe the performance of bleach-digested Zeihl-Neelsen (ZN) smears in TB suspects with/without HIV. In total, 51 (26%) and 62 (31%) out of the first 198 spot and digested smears were positive. Seven of the 30 HIV-positive patients had TB and their ZN smears were negative, scanty or 1+. Six of seven digested smears were scanty. Forty-two of 115 HIV-negative patients had TB. Eleven (26%) of their digested smears were negative, 12 (29%) scanty and 19 (45%) positive. Despite the lower bacilli numbers of HIV-positive patients, the technique had sensitivity and specificity similar to that in HIV-negative patients.

Item Type: Article
Uncontrolled Keywords: pulmonary tuberculosis ethiopia
Subjects: QY Clinical Pathology > Diagnostic Tests > QY 120 Sputum
WC Communicable Diseases > Virus Diseases > Acquired Immunodeficiency Syndrome. HIV Infections > WC 503 Acquired immunodeficiency syndrome. HIV infections
WC Communicable Diseases > Virus Diseases > Acquired Immunodeficiency Syndrome. HIV Infections > WC 503.5 Complications
WF Respiratory System > Tuberculosis > WF 200 Tuberculosis (General)
Faculty: Department: Groups (2002 - 2012) > Child & Reproductive Health Group
Groups (2002 - 2012) > Clinical Group
Digital Object Identifer (DOI): https://doi.org/10.1258/004947507779952014
Depositing User: Helen Rigby
Date Deposited: 15 Aug 2012 09:43
Last Modified: 17 Jul 2020 10:58
URI: https://archive.lstmed.ac.uk/id/eprint/1190

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