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Evaluating the Evidence for Lymphatic Filariasis Elimination

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Davis, Emma, Reimer, Lisa ORCID: https://orcid.org/0000-0002-9711-4981, Pellis, Lorenzo and Hollingsworth, Deirdre (2019) 'Evaluating the Evidence for Lymphatic Filariasis Elimination'. Trends in Parasitology, Vol 35, Issue 11, pp. 860-869.

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Abstract

In the global drive for elimination of lymphatic filariasis (LF), 15 countries have achieved validation of elimination as a public health problem (EPHP). Recent empirical evidence has demonstrated that EPHP does not always lead to elimination of transmission (EOT). Here we show how the probability of elimination explicitly depends on key biological parameters, many of which have been poorly characterized, leading to a poor evidence base for the elimination threshold. As more countries progress towards EPHP it is essential that this process is well-informed, as prematurely halting treatment and surveillance programs could pose a serious threat to global progress. We highlight that refinement of the weak empirical evidence base
is vital to understand drivers of elimination and inform long-term policy

Item Type: Article
Subjects: WA Public Health > WA 100 General works
WA Public Health > Health Problems of Special Population Groups > WA 395 Health in developing countries
WC Communicable Diseases > Tropical and Parasitic Diseases > WC 880 Filariasis and related conditions (General)
WH Hemic and Lymphatic Systems > Lymphatic System > WH 700 Lymphatic system. Lymphatic diseases (General)
Faculty: Department: Biological Sciences > Vector Biology Department
Digital Object Identifer (DOI): https://doi.org/10.1016/j.pt.2019.08.003
Depositing User: David Lee
Date Deposited: 18 Sep 2019 09:34
Last Modified: 20 Nov 2019 14:52
URI: https://archive.lstmed.ac.uk/id/eprint/12469

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