Case Report: Highlighting Male Genital Schistosomiasis (MGS) in Fishermen from the Southwestern Shoreline of Lake Malawi, Mangochi District

Kayuni, Seke, LaCourse, James ORCID: https://orcid.org/0000-0001-9261-7136, Makaula, P, Lampiao, F, Juziwelo, J, Fawcett, J, Shaw, A, Alharbi, Mohammad, Verweij, J. J and Stothard, Russell ORCID: https://orcid.org/0000-0002-9370-3420 (2019) 'Case Report: Highlighting Male Genital Schistosomiasis (MGS) in Fishermen from the Southwestern Shoreline of Lake Malawi, Mangochi District'. American Journal of Tropical Medicine and Hygiene, Vol 101, Issue 6, pp. 1331-1335.

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Abstract

Urogenital schistosomiasis causes morbidity within the genitalia but is underreported and infrequently examined in men. To draw attention to male genital schistosomiasis (MGS), a longitudinal cohort study was conducted among fishermen along the southwestern shoreline of Lake Malawi. A case series of five participants is presented inclusive of questionnaire interviews, parasitological examinations, ultrasonography, and provision of a standard dose (40 mg/kg) of praziquantel (PZQ) treatment at baseline, 1-, 3-, 6-, and 12-month follow-up time points. Eggs of Schistosoma haematobium were observed in urine or semen across all time points; parasitological diagnostics were bolstered by real-time PCR for Schistosoma DNA in semen and by portable ultrasonography to document putative MGS-associated morbidity. We highlight the importance of developing standard diagnostic tests for MGS and increasing the accessibility of PZQ treatment to men, especially those in at-risk endemic areas.

Item Type:	Article
Subjects:	WA Public Health > Health Problems of Special Population Groups > WA 395 Health in developing countries WC Communicable Diseases > Tropical and Parasitic Diseases > WC 680 Tropical diseases (General) WC Communicable Diseases > Tropical and Parasitic Diseases > WC 695 Parasitic diseases (General) WC Communicable Diseases > Tropical and Parasitic Diseases > WC 810 Schistosomiasis WJ Urogenital System > WJ 20 Research (General)
Faculty: Department:	Biological Sciences > Department of Tropical Disease Biology
Digital Object Identifer (DOI):	https://doi.org/10.4269/ajtmh.19-0562
Depositing User:	Cathy Waldron
Date Deposited:	11 Nov 2019 11:26
Last Modified:	04 Nov 2020 02:02
URI:	https://archive.lstmed.ac.uk/id/eprint/12547

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