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Dataset on in vitro maintenance of Mansonella perstans microfilariae and drug testing

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Njouendou, Abdel Jelil, Ritter, Manuel, Kien, Chi Anizette, Esum, Mathias E., Ndongmo, Winston Patrick Chounna, Fombad, Fanny Fri, Gandjui, Narcisse Victor T., Njiokou, Flobert, Enyong, Peter, Pfarr, Kenneth, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Layland, Laura E., Hoerauf, Achim and Wanji, Samuel (2020) 'Dataset on in vitro maintenance of Mansonella perstans microfilariae and drug testing'. Data in Brief, Vol 28, Issue 104930, p. 104930.

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Abstract

The data presented here were collected from in vitro culture of M. perstans microfilariae, while asssessing the ability of two basic culture media; Dulbecco’s Modified Eagle’s Medium (DMEM) and Roswell Park Memorial Institute (RPMI-1640) supplemented with 10% fetal bovine serum (FBS) and a monkey kidney epithelial cell line (LLC-MK2) to support the survival of this parasite stage; and their sussceptibility to chemotherapeutic agents. Parasites motlity were scored daily on a 4 scales system, and the average motility computed, as well as the area under the motility curve. Mortility was determined as the percentges of imotiled worms.

Item Type: Article
Subjects: W General Medicine. Health Professions > W 26.5 Informatics. Health informatics
QX Parasitology > Helminths. Annelida > QX 301 Filarioidea
WC Communicable Diseases > Tropical and Parasitic Diseases > WC 850 Nematode infections (General)
Faculty: Department: Biological Sciences > Department of Tropical Disease Biology
Digital Object Identifer (DOI): https://doi.org/10.1016/j.dib.2019.104930
Depositing User: Cathy Waldron
Date Deposited: 24 Jan 2020 10:05
Last Modified: 24 Jan 2020 10:05
URI: https://archive.lstmed.ac.uk/id/eprint/13569

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