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Dataset on in vitro maintenance of Mansonella perstans microfilariae and drug testing

Njouendou, Abdel Jelil, Ritter, Manuel, Kien, Chi Anizette, Esum, Mathias E., Ndongmo, Winston Patrick Chounna, Fombad, Fanny Fri, Gandjui, Narcisse Victor T., Njiokou, Flobert, Enyong, Peter, Pfarr, Kenneth, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Layland, Laura E., Hoerauf, Achim and Wanji, Samuel (2020) 'Dataset on in vitro maintenance of Mansonella perstans microfilariae and drug testing'. Data in Brief, Vol 28, Issue 104930, p. 104930.

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Abstract

The data presented here were collected from in vitro culture of M. perstans microfilariae, while asssessing the ability of two basic culture media; Dulbecco’s Modified Eagle’s Medium (DMEM) and Roswell Park Memorial Institute (RPMI-1640) supplemented with 10% fetal bovine serum (FBS) and a monkey kidney epithelial cell line (LLC-MK2) to support the survival of this parasite stage; and their sussceptibility to chemotherapeutic agents. Parasites motlity were scored daily on a 4 scales system, and the average motility computed, as well as the area under the motility curve. Mortility was determined as the percentges of imotiled worms.

Item Type: Article
Subjects: W General Medicine. Health Professions > W 26.5 Informatics. Health informatics
QX Parasitology > Helminths. Annelida > QX 301 Filarioidea
WC Communicable Diseases > Tropical and Parasitic Diseases > WC 850 Nematode infections (General)
Faculty: Department: Biological Sciences > Department of Tropical Disease Biology
Digital Object Identifer (DOI): https://doi.org/10.1016/j.dib.2019.104930
Depositing User: Cathy Waldron
Date Deposited: 24 Jan 2020 10:05
Last Modified: 24 Jan 2020 10:05
URI: https://archive.lstmed.ac.uk/id/eprint/13569

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