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Molecular diagnosis and equine parasitology

Hodgkinson, Jane E. (2006) 'Molecular diagnosis and equine parasitology'. Veterinary Parasitology, Vol 136, Issue 2, pp. 109-116.

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Abstract

The future implementation of improved and sustainable control strategies for the major equine parasites will be dependent on a greater insight into their basic biology, pathogenicity and epidemiology together with an enhanced ability for accurate diagnosis. This paper will provide a review of the current molecular methods under development for the detection of equine parasites and their application to current scientific questions. In particular, the strongyles are recognised as important pathogens of horses and recent advances made in the study of this parasitic group at the single species level will be addressed. The ribosomal (r)DNA region of the parasite genome has been employed to distinguish between closely related species. Molecular probes designed to this target region were used in combination with PCR technology to allow the identification of individual species within mixed infections. They have been applied to all parasite stages to look at the role of individual species in natural infection, disease and drug resistance. Similar techniques have been developed to detect other equine parasites and these will also be discussed. Further opportunities for employing existing techniques and the need for new diagnostic tools will be highlighted. (c) 2005 Elsevier B.V. All rights reserved.

Item Type: Article
Uncontrolled Keywords: horse parasite helminth strongyle diagnosis molecular babesia-equi ribosomal DNA larval cyathostomiasis inhibited development shetland ponies horses pcr identification prevalence strongyles
Subjects: QW Microbiology and Immunology > Environmental Microbiology > QW 70 Veterinary microbiology
QX Parasitology > Helminths. Annelida > QX 200 Helminths
QX Parasitology > QX 4 General works
QX Parasitology > QX 45 Host-parasite relations
Faculty: Department: Groups (2002 - 2012) > Veterinary Parasitology Group (2002-2008)
Digital Object Identifer (DOI): https://doi.org/10.1016/j.vetpar.2005.12.006
Depositing User: Sarah Lewis-Newton
Date Deposited: 13 May 2011 14:25
Last Modified: 06 Feb 2018 13:01
URI: http://archive.lstmed.ac.uk/id/eprint/1508

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