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Piloting post-exposure prophylaxis in Kenya raises specific concerns for the management of childhood rape

Speight, C. G., Klufio, A., Kilonzo, S. N., Mbugua, C., Kuria, E., Bunn, J. and Taegtmeyer, Miriam ORCID: https://orcid.org/0000-0002-5377-2536 (2006) 'Piloting post-exposure prophylaxis in Kenya raises specific concerns for the management of childhood rape'. Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol 100, Issue 1, pp. 14-18.

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Abstract

Thika District, Kenya, is the site of an operational research study on the provision of comprehensive post-rape care, including the free provision of HIV post-exposure prophylaxis (PEP). It is a typical rural Kenyan district in terms of resources and patient throughput. The high rate of children attending for post-rape services was unexpected and had significant programming implications. An age-disaggregated analysis of existing quantitative data from the first 8 months of service provision was conducted. Ninety-four case records were reviewed, of whom 48 (51%) were in the age range 1.5-17 years inclusive. All three cases of mate rape were in children. Children were more likely to know their assailant than adults and were more likely to be HIV-negative at baseline. The majority (86%) of children presented in time for PEP, with adherence and completion rates similar to adults but lower rates of 6-week follow-up. The use of weight bands to determine drug dosages greatly simplified the appropriate and early administration of paediatric PEP. The high rates of childhood rape and demand for post-rape services were an enormous challenge for service providers and policy-makers. (c) 2005 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.

Item Type: Article
Uncontrolled Keywords: hiv vct post-exposure prophylaxis lamivudine zidovudine human-immunodeficiency-virus infection exposure
Subjects: WC Communicable Diseases > Sexually Transmitted Diseases > WC 140 Sexually transmitted diseases
WC Communicable Diseases > Virus Diseases > Acquired Immunodeficiency Syndrome. HIV Infections > WC 503 Acquired immunodeficiency syndrome. HIV infections
WC Communicable Diseases > Virus Diseases > Acquired Immunodeficiency Syndrome. HIV Infections > WC 503.2 Therapy
WC Communicable Diseases > Virus Diseases > Acquired Immunodeficiency Syndrome. HIV Infections > WC 503.3 Etiology. Transmission
WS Pediatrics > Child Care. Nutrition. Physical Examination > WS 135 Prophylactic immunizations
WS Pediatrics > WS 20 Research (General)
Faculty: Department: Groups (2002 - 2012) > Clinical Group
Digital Object Identifer (DOI): https://doi.org/10.1016/j.trstmh.2005.06.026
Depositing User: Sarah Lewis-Newton
Date Deposited: 12 Apr 2011 10:40
Last Modified: 06 Feb 2018 13:02
URI: http://archive.lstmed.ac.uk/id/eprint/1595

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