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Pneumococcal conjugate vaccines for preventing acute otitis media in children

Sévaux, Joline LH, Venekamp, Roderick P, Lutje, Vittoria, Hak, Eelko, Schilder, Anne, Sanders, Elisabeth and Damoiseaux, Roger (2020) 'Pneumococcal conjugate vaccines for preventing acute otitis media in children'. Cochrane Database of Systematic Reviews, Vol 11, CD001480.

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Abstract

Background
Prior to introducing pneumococcal conjugate vaccines (PCVs), Streptococcus pneumoniae was most commonly isolated from the middle ear fluid of children with acute otitis media (AOM). Reducing nasopharyngeal colonisation of this bacterium by PCVs may lead to a decline in AOM. The effects of PCVs deserve ongoing monitoring since studies from the post‐PCV era report a shift in causative otopathogens towards non‐vaccine serotypes and other bacteria. This updated Cochrane Review was first published in 2002 and updated in 2004, 2009, 2014, and 2019.

Item Type: Article
Subjects: QW Microbiology and Immunology > Immunotherapy and Hypersensitivity > QW 805 Vaccines. Antitoxins. Toxoids
WS Pediatrics > Diseases of Children and Adolescents > General Diseases > WS 200 General works
WV Otolaryngology > Ear > WV 200 General works
Faculty: Department: Clinical Sciences & International Health > Clinical Sciences Department
Digital Object Identifer (DOI): https://doi.org/10.1002/14651858.CD001480.pub6
Depositing User: Christianne Esparza
Date Deposited: 08 Dec 2020 20:11
Last Modified: 24 Nov 2021 02:02
URI: https://archive.lstmed.ac.uk/id/eprint/16263

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