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Sequencing of Culex quinquefasciatus Establishes a Platform for Mosquito Comparative Genomics

Arensburger, P., Megy, K., Waterhouse, R. M., Abrudan, J., Amedeo, P., Antelo, B., Bartholomay, L., Bidwell, S., Caler, E., Camara, F., Campbell, C. L., Campbell, K. S., Casola, C., Castro, M. T., Chandramouliswaran, I., Chapman, S. B., Christley, S., Costas, J., Eisenstadt, E., Feschotte, C., Fraser-Liggett, C., Guigo, R., Haas, B., Hammond, M., Hansson, B. S., Hemingway, Janet ORCID: https://orcid.org/0000-0002-3200-7173, Hill, S. R., Howarth, C., Ignell, R., Kennedy, R. C., Kodira, C. D., Lobo, N. F., Mao, C., Mayhew, G., Michel, K., Mori, A., Liu, N., Naveira, H., Nene, V., Nguyen, N., Pearson, M. D., Pritham, E. J., Puiu, D., Qi, Y., Ranson, Hilary ORCID: https://orcid.org/0000-0003-2332-8247, Ribeiro, J. M. C., Roberston, H. M., Severson, D. W., Shumway, M., Stanke, M., Strausberg, R. L., Sun, C., Sutton, G., Tu, Z., Tubio, J. M. C., Unger, M. F., Vanlandingham, D. L., Vilella, A. J., White, O., White, J. R., Wondji, Charles ORCID: https://orcid.org/0000-0003-0791-3673, Wortman, J., Zdobnov, E. M., Birren, B., Christensen, B. M., Collins, F. H., Cornel, A., Dimopoulos, G., Hannick, L. I., Higgs, S., Lanzaro, G. C., Lawson, D., Lee, N. H., Muskavitch, M. A. T., Raikhel, A. S. and Atkinson, P. W. (2010) 'Sequencing of Culex quinquefasciatus Establishes a Platform for Mosquito Comparative Genomics'. Science, Vol 330, Issue 6000, pp. 86-88.

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Abstract

Culex quinquefasciatus (the southern house mosquito) is an important mosquito vector of viruses such as West Nile virus and St. Louis encephalitis virus, as well as of nematodes that cause lymphatic filariasis. C. quinquefasciatus is one species within the Culex pipiens species complex and can be found throughout ropical and temperate climates of the world. The ability of C. quinquefasciatus to take blood meals from birds, livestock, and humans contributes to its ability to vector pathogens between species. Here, we describe the genomic sequence of C. quinquefasciatus: Its repertoire of 18,883 protein-coding genes is 22% larger than that of Aedes aegypti and 52% larger than that of Anopheles gambiae with multiple gene-family expansions, including olfactory and gustatory receptors, salivary gland genes, and genes associated with xenobiotic detoxification.

Item Type: Article
Subjects: QU Biochemistry > Genetics > QU 450 General Works
QX Parasitology > Helminths. Annelida > QX 203 Nematoda
QX Parasitology > Helminths. Annelida > QX 301 Filarioidea
QX Parasitology > Insects. Other Parasites > QX 510 Mosquitoes
QX Parasitology > Insects. Other Parasites > QX 530 Culex
QX Parasitology > Insects. Other Parasites > QX 650 Insect vectors
WC Communicable Diseases > Virus Diseases > Viral Hemorrhagic Fevers. Other Virus Diseases > WC 542 Arbovirus encephalitis. Equine encephalomyelitis (in humans)
Faculty: Department: Groups (2002 - 2012) > Vector Group
Digital Object Identifer (DOI): https://doi.org/10.1126/science.1191864
Depositing User: Users 183 not found.
Date Deposited: 08 Oct 2010 11:54
Last Modified: 06 Feb 2018 13:02
URI: http://archive.lstmed.ac.uk/id/eprint/1660

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