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Comparison of scanty AFB smears against culture in an area with high HIV prevalence

Lawson, Lovett, Yassin, Mohammed A., Ramsay, Andrew, Emenyonu, N. E., Squire, Bertie ORCID: https://orcid.org/0000-0001-7173-9038 and Cuevas, Luis ORCID: https://orcid.org/0000-0002-6581-0587 (2005) 'Comparison of scanty AFB smears against culture in an area with high HIV prevalence'. International Journal of Tuberculosis and Lung Disease, Vol 9, Issue 8, pp. 933-935.

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Abstract

To verify among tuberculosis (TB) suspects attending hospitals in Abuja, Nigeria, if sputum smears graded as scanty are false-positive, sputum smears from 1068 patients were graded with the International Union Against Tuberculosis and Lung Disease classification. One specimen was cultured. Eight hundred and twenty-four (26%) smears were positive, 137 (4%) scanty and 2243 negative. Of 1068 cultures, 680 (64%) were positive. One hundred and thirty (95%) scanty and 809 (98%) positive smears were culture-positive. Twelve of 18 patients with a single scanty smear and 51 of 52 with >= 2 scanty smears were culture-positive. Fewer than < 5% scanty results, < 1% of the patients treated for TB, are false-positive.

Item Type: Article
Additional Information: No DOI
Uncontrolled Keywords: tuberculosis diagnosis nigeria scanty bacilli smears pulmonary tuberculosis
Subjects: QY Clinical Pathology > QY 25 Laboratory techniques and procedure
WC Communicable Diseases > Virus Diseases > Acquired Immunodeficiency Syndrome. HIV Infections > WC 503 Acquired immunodeficiency syndrome. HIV infections
WF Respiratory System > Tuberculosis > WF 220 Diagnosis. Prognosis
Faculty: Department: Groups (2002 - 2012) > Child & Reproductive Health Group
Groups (2002 - 2012) > Clinical Group
Depositing User: Martin Chapman
Date Deposited: 22 Nov 2011 14:44
Last Modified: 06 Feb 2018 13:02
URI: https://archive.lstmed.ac.uk/id/eprint/1907

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