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A case for a Glossina genome project

Aksoy, S., Berriman, M., Hall, N., Hattori, M., Hide, W. and Lehane, Mike (2005) 'A case for a Glossina genome project'. Trends in Parasitology, Vol 21, Issue 3, pp. 107-111.

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Abstract

Given the medical and agricultural significance of Glossina, knowledge of the genomic aspects of the vector and vector-pathogen interactions are a high priority. In preparation for a full genome sequence initiative, an extensive set of expressed sequence tags (ESTs) has been generated from tissue-specific normalized libraries. In addition, bacterial artificial chromosome (BAC) libraries are being constructed, and information on the genome structure and size from different species has been obtained. An international consortium is now in place to further efforts to lead to a full genome project.

Item Type: Article
Uncontrolled Keywords: human african trypanosomiasis sleeping sickness tsetse-flies immune-responses drug-resistance transmission sequence midgut vector expression
Subjects: QU Biochemistry > Genetics > QU 470 Genetic structures
QX Parasitology > Insects. Other Parasites > QX 505 Diptera
WC Communicable Diseases > Tropical and Parasitic Diseases > WC 705 Trypanosomiasis
Faculty: Department: Groups (2002 - 2012) > Vector Group
Digital Object Identifer (DOI): https://doi.org/10.1016/j.pt.2005.01.006
Depositing User: Ms Julia Martin
Date Deposited: 03 Nov 2011 16:57
Last Modified: 06 Feb 2018 13:03
URI: http://archive.lstmed.ac.uk/id/eprint/1971

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