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Malaria parasite transporters as a drug-delivery strategy

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Bray, Patrick (2005) 'Malaria parasite transporters as a drug-delivery strategy'. Trends in Parasitology, Vol 21, Issue 7, pp. 299-301.

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Abstract

The recent characterization of the choline carrier of the malaria parasite and its role in the selective delivery of novel antimalarial drugs has reignited interest in parasite transporters as a drug-delivery strategy. In this article, we discuss these findings in relation to the wider context of developing a sustainable antimalarial-drug-development portfolio.

Item Type: Article
Uncontrolled Keywords: infected human-erythrocytes red-blood-cells plasmodium-falciparum phospholipid-metabolism permeability pathways antimalarial activity potent inhibitors host erythrocyte choline uptake membrane
Subjects: QX Parasitology > QX 45 Host-parasite relations
WB Practice of Medicine > Therapeutics > WB 340 Drug Administration
WC Communicable Diseases > Tropical and Parasitic Diseases > WC 750 Malaria
Faculty: Department: Groups (2002 - 2012) > Molecular & Biochemical Parasitology Group
Digital Object Identifer (DOI): https://doi.org/10.1016/j.pt.2005.05.013
Depositing User: Sarah Lewis-Newton
Date Deposited: 07 Oct 2011 15:39
Last Modified: 06 Feb 2018 13:03
URI: http://archive.lstmed.ac.uk/id/eprint/1972

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