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Transfusion‐Transmitted Malaria in Countries Where Malaria Is Endemic: A Review of the Literature from Sub‐Saharan Africa

Owusu‐Ofori, Alex K., Parry, Christopher and Bates, Imelda ORCID: https://orcid.org/0000-0002-0862-8199 (2010) 'Transfusion‐Transmitted Malaria in Countries Where Malaria Is Endemic: A Review of the Literature from Sub‐Saharan Africa'. Clinical Infectious Diseases, Vol 51, Issue 10, pp. 1192-1198.

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Abstract

Although international policies recommend that blood for transfusion should be screened for transfusiontransmitted infections, malaria screening is not performed in most malaria-endemic countries in sub-Saharan Africa. Our literature review identified 17 relevant studies from the period 1980–2009 and indicated that the median prevalence of malaria among 33,029 blood donors was 10.2% (range, 0.7% in Kenya to 55.0% in Nigeria). Malaria screening methods, including microscopy (used in 16 of 17 studies), are either insensitive or impractical for donor screening in resource-poor countries. Even if a suitable screening method were available, rejection of malaria-positive donors would jeopardize the blood supply. Only 1 study established the prevalence of parasitemia among transfusion recipients. This review highlights the need for more evidence about the clinical impact of transfusion-transmitted malaria to justify the policy of screening for blood for malaria in areas of endemicity and for a critical analysis of the feasibility of implementing such a policy and its effect on blood supply.

Item Type: Article
Subjects: WB Practice of Medicine > Therapeutics > WB 356 Blood transfusion
WB Practice of Medicine > Medical Climatology > WB 710 Diseases of geographic areas
WC Communicable Diseases > Tropical and Parasitic Diseases > WC 750 Malaria
WC Communicable Diseases > Tropical and Parasitic Diseases > WC 755 Epidemiology
WC Communicable Diseases > Tropical and Parasitic Diseases > WC 770 Therapy
Digital Object Identifer (DOI): https://doi.org/10.1086/656806
Depositing User: Tina Bowers
Date Deposited: 01 Jul 2011 11:41
Last Modified: 15 Jun 2018 14:35
URI: https://archive.lstmed.ac.uk/id/eprint/2070

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