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Sex hormone patterns and serum retinol concentrations in adolescent girls

Brabin, L., Roberts, C., Barr, F., Agbaje, S., Harper, Gregory and Briggs, N. (2004) 'Sex hormone patterns and serum retinol concentrations in adolescent girls'. Journal of Reproductive Medicine, Vol 49, Issue 1, pp. 41-51.

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OBJECTIVE: To describe the pattern and relation of sex serum hormones and retinol concentrations over 1 menstrual cycle in adolescent girls living in a resource-poor setting.
STUDY DESIGN: Venous blood samples were collected on alternate days of the cycle, and estrogen, progesterone, luteinizing hormone (LH), follicle stimulating hormone and serum retinol were measured. A linear random effects model was used to examine the relationship between sex hormones and serum retinol.
RESULTS: Twenty-eight girls were studied. During the follicular phase, serum retinol was associated negatively with progesterone and positively with LH. In the luteal phase, serum retinol was positively associated with estrogen. Serum retinol increased in the follicular phase but not the luteal phase. Sex hormone and serum retinol concentrations showed marked individual and day-today variability. Two girls maintained serum retinol concentrations >0.7 mumol/L throughout the cycle. Six remained at <0.7 mumol/L, which indicated subclinical deficiency.
CONCLUSION: This study indicated that in adolescent girls, sex hormone patterns correlate significantly with serum retinol, and in vitamin A-deficient girls this could be important for reproductive function.

Item Type: Article
Uncontrolled Keywords: sex hormones retinol adolescence vitamin a deficiency vitamin-a status beta-carotene menstrual cycles binding protein night blindness pregnancy growth nepal supplementation reproduction
Subjects: WK Endocrine System > WK 20 Research (General)
WS Pediatrics > By Age Groups > WS 460 Adolescence (General)
Faculty: Department: Groups (2002 - 2012) > Child & Reproductive Health Group
Depositing User: Martin Chapman
Date Deposited: 05 Sep 2012 10:02
Last Modified: 06 Feb 2018 13:03


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