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Malaria in pregnancy and the endemicity spectrum: what can we learn?

Nosten, F., Rogerson, S. J., Beeson, J. G., McGready, R., Mutabingwa, T. K. and Brabin, Bernard (2004) 'Malaria in pregnancy and the endemicity spectrum: what can we learn?'. Trends in Parasitology, Vol 20, Issue 9, pp. 425-432.

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Abstract

The increased susceptibility of pregnant women to malaria infection has long been recognized, but the magnitude of the disease burden in this particular group, together with the pathophysiology of maternal malaria and the specific difficulties in treatment, have only recently been the focus of research. Most research on maternal malaria has derived from sub-Saharan Africa where transmission is high, whereas most of the studies on the treatment of malaria and the effect of non-falciparum species has been conducted in low-transmission areas of Asia. In this paper, we attempt to improve our understanding of the disease and its mechanisms from observed differences and similarities between contrasting areas of transmission, and to identify priorities for future research.

Item Type: Article
Uncontrolled Keywords: falciparum-infected erythrocytes chondroitin sulfate-a intrauterine growth-retardation plasmodium-vivax malaria variant surface-antigens placental malaria infant-mortality rural malawi birth-weight cytoadherence characteristics
Subjects: WA Public Health > WA 105 Epidemiology
WC Communicable Diseases > Tropical and Parasitic Diseases > WC 750 Malaria
WC Communicable Diseases > Tropical and Parasitic Diseases > WC 755 Epidemiology
WQ Obstetrics > WQ 20 Research (General)
WQ Obstetrics > Pregnancy > WQ 200 General works
WQ Obstetrics > Pregnancy Complications > WQ 256 Infectious diseases
Faculty: Department: Groups (2002 - 2012) > Child & Reproductive Health Group
Digital Object Identifer (DOI): https://doi.org/10.1016/j.pt.2004.06.007
Depositing User: Sarah Lewis-Newton
Date Deposited: 22 Mar 2012 17:30
Last Modified: 06 Feb 2018 13:03
URI: http://archive.lstmed.ac.uk/id/eprint/2240

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