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Role of Vector Control in the Global Program to Eliminate Lymphatic Filariasis

Bockarie, Moses, Pedersen, E. M., White, G. B. and Michael, E. (2009) 'Role of Vector Control in the Global Program to Eliminate Lymphatic Filariasis'. Annual Review of Entomology, Vol 54, pp. 469-487.

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Abstract

Lymphatic filariasis (LF) is a major cause of acute and chronic morbidity in the tropical and subtropical parts of the world. The availability of safe, single-dose, drug treatment regimens capable of suppressing microfilaremia to very low levels, along with improvements in techniques for diagnosing infection, has resulted in the targeting of this major mosquito-borne disease for global elimination. The Global Program to Eliminate Lymphatic Filariasis (GPELF) was launched in 2000 with the principal objective of breaking the cycles of transmission of Wuchereria bancrofti and Brugia spp. through the application of annual mass drug administrations (MDAs) to entire at-risk populations. Although significant progress in initiating MDA programs in endemic countries has been made, emerging challenges to this approach have raised questions regarding the effectiveness of using MDA alone to eliminate I-F without the inclusion of supplementary vector control. Here, we review advances in knowledge of vector ecology, vector-parasite relationships, and both empirical and theoretical evidence regarding vector management to assess the feasibility and strategic value of including vector control in the GPELF initiative to achieve the global elimination of LF.

Item Type: Article
Additional Information: 394VX Times Cited:0 Cited References Count:87
Uncontrolled Keywords: mosquito ecology mass drug administration mathematical modeling insecticide treated nets integrated vector management papua-new-guinea wuchereria-bancrofti infection dar-es-salaam culex-quinquefasciatus transmission dynamics polystyrene beads mosquito-control solomon-islands pit latrines transmitted filariasis
Subjects: WB Practice of Medicine > Therapeutics > WB 300 General works
QX Parasitology > Insects. Other Parasites > QX 530 Culex
QX Parasitology > Insects. Other Parasites > QX 650 Insect vectors
QV Pharmacology > QV 4 General works
QV Pharmacology > QV 38 Drug action.
WB Practice of Medicine > Therapeutics > WB 340 Drug Administration
WC Communicable Diseases > Tropical and Parasitic Diseases > WC 880 Filariasis and related conditions (General)
WB Practice of Medicine > Therapeutics > WB 330 Drug therapy
QX Parasitology > Insects. Other Parasites > QX 510 Mosquitoes
QX Parasitology > Insects. Other Parasites > QX 600 Insect control. Tick control
Faculty: Department: Groups (2002 - 2012) > Disease Control Strategy Group
Digital Object Identifer (DOI): https://doi.org/10.1146/annurev.ento.54.110807.090626
Depositing User: Users 67 not found.
Date Deposited: 22 Mar 2010 17:50
Last Modified: 06 Feb 2018 12:59
URI: http://archive.lstmed.ac.uk/id/eprint/235

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