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Use of pneumococcal polysaccharide vaccines: No simple answers

French, Neil (2003) 'Use of pneumococcal polysaccharide vaccines: No simple answers'. Journal of Infection, Vol 46, Issue 2, pp. 78-86.

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Abstract

Control of pneumococcal disease by vaccination with capsular polysaccharide has been investigated and promoted with variable enthusiasm for the past 90 years. Despite this the true value of the 23-valent pneumococcal polysaccharide vaccine remains unclear. In particular the ability of this vaccine to provide durable protection in those who require it most is in greatest doubt. With the introduction of the protein-conjugated pneumococcal polysaccharide vaccines new opportunities for prevention exist, but it will be import to rigorously assess their role in at-risk groups to avoid the uncertainty that surrounds the older simple polysaccharide products.

Item Type: Article
Subjects: QW Microbiology and Immunology > Immunotherapy and Hypersensitivity > QW 805 Vaccines. Antitoxins. Toxoids
WA Public Health > Preventive Medicine > WA 115 Immunization
WC Communicable Diseases > Infection. Bacterial Infections > Bacterial Infections > WC 210 Streptococcal infections (General or not elsewhere classified)
WC Communicable Diseases > Infection. Bacterial Infections > Bacterial Infections > WC 217 Pneumococcal infections
Faculty: Department: Groups (2002 - 2012) > Clinical Group
Digital Object Identifer (DOI): https://doi.org/10.1053/jinf.2002.1113
Depositing User: Lynn Roberts-Maloney
Date Deposited: 06 Feb 2014 12:34
Last Modified: 06 Feb 2018 13:04
URI: https://archive.lstmed.ac.uk/id/eprint/2544

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