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Umbilical-cord blood for transfusion in children with severe anaemia in under-resourced countries

Hassall, Oliver, Bedu-Addo, G., Adarkwa, M., Danso, K. and Bates, Imelda ORCID: https://orcid.org/0000-0002-0862-8199 (2003) 'Umbilical-cord blood for transfusion in children with severe anaemia in under-resourced countries'. Lancet, Vol 361, Issue 9358, pp. 678-679.

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Abstract

Shortage of blood for transfusion contributes substantially to mortality of children with severe anaemia in sub-Saharan Africa. Umbilical-cord blood could be an additional and readily available source of blood. We aimed to show whether it is possible to gather cord blood in a busy Ghanaian labour ward. Mean volume of each blood sample obtained from the umbilical cord was 85 mL (SID 28.0). This amount of blood is sufficient to raise the haemoglobin concentrations of 28 (21%) of 131 children needing transfusions in the same hospital, by 30 g/L. Further work is needed to improve the sterility of cord blood and to establish the resource and logistical implications of scaling-up for sub-Saharan Africa transfusion services.

Item Type: Article
Subjects: WA Public Health > WA 30 Socioeconomic factors in public health (General)
WA Public Health > Health Problems of Special Population Groups > WA 395 Health in developing countries
WB Practice of Medicine > Therapeutics > WB 356 Blood transfusion
WH Hemic and Lymphatic Systems > Hematologic Diseases. Immunologic Factors. Blood Banks > WH 155 Anemia
WS Pediatrics > By Age Groups > WS 430 Infancy
Faculty: Department: Groups (2002 - 2012) > Disease Control Strategy Group
Digital Object Identifer (DOI): https://doi.org/10.1016/s0140-6736(03)12565-2
Depositing User: Users 476 not found.
Date Deposited: 29 Nov 2012 14:08
Last Modified: 06 Feb 2018 13:04
URI: http://archive.lstmed.ac.uk/id/eprint/2565

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