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In routine UK hospital practice T-SPOT.TB™ is useful in some patients with a modest pre-test probability of active tuberculosis.

Turtle, Lance, Kemp, Tim, Davies, Geraint R, Squire, Bertie ORCID: https://orcid.org/0000-0001-7173-9038, Beeching, Nicholas and Beadsworth, M. (2012) 'In routine UK hospital practice T-SPOT.TB™ is useful in some patients with a modest pre-test probability of active tuberculosis.'. European journal of internal medicine, Vol 23, Issue 4, pp. 363-7.

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Abstract

Although it can add weight to a clinical diagnosis, T-SPOT.TB™ assay is not reliable for the diagnosis of active tuberculosis in a real world setting where the test is often used in patients with smear negative or extra-pulmonary disease. The test is useful for ruling out disease in HIV negative patients.

Item Type: Article
Uncontrolled Keywords: Tuberculosis; Sensitivity and specificity; ELISpot; Interferon-gamma release assay
Subjects: WF Respiratory System > Tuberculosis > WF 220 Diagnosis. Prognosis
Faculty: Department: Groups (2002 - 2012) > Clinical Group
Digital Object Identifer (DOI): https://doi.org/10.1016/j.ejim.2012.01.002,
Depositing User: Helen Rigby
Date Deposited: 28 May 2012 14:31
Last Modified: 06 Feb 2018 13:04
URI: http://archive.lstmed.ac.uk/id/eprint/2847

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