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Chronic virus infections supress atopy but not asthma in a set of children from a large Latin American city: a cross-section study.

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Veiga, Rafael V., Cunha, Sergio S., Dattoli, Vitor C. C., Cruz, Álvaro C., Cooper, Philip, Rodrigues, Laura C., Barreto, Maurício L. and Alcantara-Neves, Neuza M. (2011) 'Chronic virus infections supress atopy but not asthma in a set of children from a large Latin American city: a cross-section study.'. BMC pulmonary medicine, Vol 11, Issue 24.

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Abstract

These data do not support previous data showing a protective effect of HAV against atopy, but did show inverse associations between SPT+ (but not specific IgE+) and infections with HSV and EBV. These findings suggest that different viral infections may protect against SPT+ in different settings and may indicate an immunoregulatory role of such infections on immediate hypersensitivity responses. The data provide no support for a protective effect of viral infections against asthma in this population.

Item Type: Article
Additional Information: The electronic version of this article is the complete one and can be found online at: http://www.biomedcentral.com/1471-2466/11/24
Uncontrolled Keywords: Asthma; Allergies
Subjects: QW Microbiology and Immunology > Immunotherapy and Hypersensitivity > QW 900 Anaphylaxis and hypersensitivity. Allergens
WA Public Health > WA 30 Socioeconomic factors in public health (General)
WC Communicable Diseases > Virus Diseases > General Virus Diseases > WC 500 Virus diseases (General or not elsewhere classified)
WF Respiratory System > WF 140 Diseases of the respiratory system (General)
WS Pediatrics > Diseases of Children and Adolescents > By System > WS 280 Respiratory system
Faculty: Department: Groups (2002 - 2012) > Molecular & Biochemical Parasitology Group
Digital Object Identifer (DOI): https://doi.org/10.1186/1471-2466-11-24
Depositing User: Mary Creegan
Date Deposited: 09 Jul 2012 10:17
Last Modified: 06 Feb 2018 13:04
URI: https://archive.lstmed.ac.uk/id/eprint/2863

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