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Plasma HIV burden in Malawian children co-infected with rotavirus

Jere, C., Cunliffe, N. A., Hoffman, I. F., Stewart, P. W., Kilaru, R., Broadhead, R. L., Molyneux, Malcolm E, Hart, C. Anthony and Fiscus, S. A. (2001) 'Plasma HIV burden in Malawian children co-infected with rotavirus'. AIDS, Vol 15, Issue 11, pp. 1439-1442.

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Abstract

Fifty-eight HIV-infected children with acute rotavirus diarrhea were tested for plasma HIV RNA. There was no difference between acute and convalescent mean viral loads, and little change in the CD4 cell counts. Compared with the 16 children who died within 4 weeks, 31 survivors had slightly lower viral loads at presentation and significantly higher CD4 cell counts. Low CD4 cell counts, but not HIV-1-RNA concentrations, were predictive of death. Local, enteric rotavirus infection did not appear to affect blood HIV viral load or CD4 cell counts in this small group of children.

Item Type: Article
Additional Information: Presented in part at the 13th International AIDS Conference Durban, South Africa, July 2000
Subjects: QU Biochemistry > Cells and Genetics > QU 375 Cell physiology
WC Communicable Diseases > Virus Diseases > General RNA Virus Infections > WC 501 RNA virus infections (General or not elsewhere classified)
WC Communicable Diseases > Virus Diseases > Acquired Immunodeficiency Syndrome. HIV Infections > WC 503 Acquired immunodeficiency syndrome. HIV infections
WH Hemic and Lymphatic Systems > Hematologic Diseases. Immunologic Factors. Blood Banks > WH 400 Fluid elements. Plasma. Serum. Blood proteins. Blood protein disorders
WS Pediatrics > By Age Groups > WS 430 Infancy
Faculty: Department: Pre 2002
Digital Object Identifer (DOI): https://doi.org/10.1097/00002030-200107270-00016
Depositing User: Lynn Roberts-Maloney
Date Deposited: 04 Oct 2013 09:12
Last Modified: 06 Feb 2018 13:05
URI: http://archive.lstmed.ac.uk/id/eprint/3165

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