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Visceral leishmaniasis: elimination with existing interventions

Matlashewski, Greg, Arana, Byron, Kroeger, Axel, Battacharaya, Sujit, Sundar, Shyam, Das, Pradeep, Sinha, Prabhat Kumar, Rijal, Suman, Mondal, Dinesh, Zilberstein, Dan and Alvar, Jorge (2011) 'Visceral leishmaniasis: elimination with existing interventions'. Lancet Infectious Diseases, Vol 11, Issue 4, pp. 322-325.

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The world’s burden of infectious diseases can be substantially reduced by more-eff ective use of existing interventions.
Advances in case detection, diagnosis, and treatment strategies have made it possible to consider the elimination of
visceral leishmaniasis in the Indian subcontinent. The priority must now be to eff ectively implement existing
interventions at the community level by actively fi nding cases in endemic villages and treating them with single-dose
liposomal amphotericin B at primary-health-care centres. Once the elimination target of one case per 10 000 population
has been reached, combination therapies involving miltefosine and paromomycin can be introduced to ensure longterm
availability of several drugs for visceral leishmaniasis and to protect against resistance.

Item Type: Article
Subjects: WA Public Health > Preventive Medicine > WA 110 Prevention and control of communicable diseases. Transmission of infectious diseases
WC Communicable Diseases > Tropical and Parasitic Diseases > WC 715 Visceral leishmaniasis
Digital Object Identifer (DOI):
Depositing User: Rachel Dominguez
Date Deposited: 18 Mar 2013 15:14
Last Modified: 02 Mar 2018 12:00


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