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Shrinking the lymphatic filariasis map: update on diagnostic tools for mapping and transmission monitoring

Rebollo, Maria and Bockarie, Moses (2014) 'Shrinking the lymphatic filariasis map: update on diagnostic tools for mapping and transmission monitoring'. Parasitology, Vol 141, Issue 14, pp. 1912-1917.

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Abstract

Summary: Lymphatic filariasis (LF), which is highly endemic in 73 countries worldwide, is targeted for elimination by 2020. The strategy for achieving this goal is based on 4 sequential programmatic steps: mapping, Mass drug administration (MDA) implementation, post-MDA surveillance and verification of LF elimination. All 4 stages of the implementation process are dependent on the availability of user friendly and highly sensitive rapid diagnostic tools. By the end of 2012, 59 countries had completed mapping for LF and Eritrea was the only country yet to start the process. Rolling out new diagnostic tools to facilitate the mapping process will enable an accelerated shrinking of the LF map to zero endemic countries by 2020. When the Global Programme to Eliminate Lymphatic Filariasis was launched in 2000, diagnostic tools for LF were limited to clinical examination, detection of microfilaria (MF) by microscopy in night blood samples and detection of antibodies to native-antigen preparations. There has been a significant improvement in the traditional LF diagnostic methods in recent years and some new tools are now available. This paper provides an update on the human diagnostic tests available for LF and their current applications as tools in mapping and transmission monitoring. The values of entomological indicators and parasite detection and speciation methods applied to vector populations are also discussed.

Item Type: Article
Additional Information: (Symposia of the British Society for Parasitology Volume 52 Advances in diagnostics for parasitic diseases)
Subjects: QX Parasitology > Helminths. Annelida > QX 301 Filarioidea
WA Public Health > WA 30 Socioeconomic factors in public health (General)
WA Public Health > Statistics. Surveys > WA 900 Public health statistics
WB Practice of Medicine > Diagnosis > General Diagnosis > WB 141 General works
WB Practice of Medicine > Therapeutics > WB 340 Drug Administration
WC Communicable Diseases > Tropical and Parasitic Diseases > WC 880 Filariasis and related conditions (General)
Faculty: Department: Biological Sciences > Department of Tropical Disease Biology
Digital Object Identifer (DOI): https://doi.org/10.1017/S0031182014001231
Depositing User: Martin Chapman
Date Deposited: 27 Oct 2014 17:02
Last Modified: 06 Feb 2018 13:07
URI: http://archive.lstmed.ac.uk/id/eprint/4511

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