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VenUS IV (Venous leg Ulcer Study IV) – compression hosiery compared with compression bandaging in the treatment of venous leg ulcers: a randomised controlled trial, mixed-treatment comparison and decision-analytic model

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Ashby, Rebecca L, Gabe, Rhian, Ali, Shehzad, Saramago, Pedro, Chuang, Ling-Hsiang, Adderley, Una, Bland, J Martin, Cullum, Nicky A, Dumville, Jo C, Iglesias, Cynthia P, Kang-ombe, Arthur, Soares, Marta O, Stubbs, Nikki C and Torgerson, David J (2014) 'VenUS IV (Venous leg Ulcer Study IV) – compression hosiery compared with compression bandaging in the treatment of venous leg ulcers: a randomised controlled trial, mixed-treatment comparison and decision-analytic model'. Health Technology Assessment, Vol 18, Issue 57, pp. 1-294.

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Abstract

Compression is an effective and recommended treatment for venous leg ulcers. Although the four-layer bandage (4LB) is regarded as the gold standard compression system, it is recognised that the amount of compression delivered might be compromised by poor application technique. Also the bulky nature of the bandages might reduce ankle or leg mobility and make the wearing of shoes difficult. Two-layer compression hosiery systems are now available for the treatment of venous leg ulcers. Two-layer hosiery (HH) may be advantageous, as it has reduced bulk, which might enhance ankle or leg mobility and patient adherence. Some patients can also remove and reapply two-layer hosiery, which may encourage self-management and could reduce costs. However, little robust evidence exists about the effectiveness of two-layer hosiery for ulcer healing and no previous trials have compared two-layer hosiery delivering ‘high’ compression with the 4LB.

Item Type: Article
Subjects: W General Medicine. Health Professions > Health Services. Patients and Patient Advocacy > W 84 Health services. Delivery of health care
WB Practice of Medicine > Therapeutics > WB 305 Instructions or non-drug prescriptions for devices or therapy (General)
WE Musculoskeletal System > WE 800 Extremities > WE 850 Lower extremity. Hip. Leg. Foot.
WR Dermatology > WR 20 Research (General)
WR Dermatology > Neoplasms. Ulcers. Occupational Dermatitis. Therapy > WR 598 Skin ulcers
Faculty: Department: Clinical Sciences & International Health > Clinical Sciences Department
Digital Object Identifer (DOI): https://doi.org/10.3310/hta18570
Depositing User: Lynn Roberts-Maloney
Date Deposited: 18 Dec 2014 10:51
Last Modified: 06 Feb 2018 13:08
URI: https://archive.lstmed.ac.uk/id/eprint/4660

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