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Rock, Kat S, le Rutte, Epke A, de Vlas, Sake J, Adams, Emily 
ORCID: https://orcid.org/0000-0002-0816-2835, Medley, Graham F and Hollingsworth, T Deirdre
(2015)
'Uniting mathematics and biology for control of visceral leishmaniasis.'. Trends in parasitology, Vol 31, Issue 6, pp. 251-259.
Abstract
The neglected tropical disease (NTD) visceral leishmaniasis (VL) has been targeted by the WHO for elimination as a public health problem on the Indian subcontinent by 2017 or earlier. To date there is a surprising scarcity of mathematical models capable of capturing VL disease dynamics, which are widely considered central to planning and assessing the efficacy of interventions. The few models that have been developed are examined, highlighting the necessity for better data to parameterise and fit these and future models. In particular, the characterisation and infectiousness of the different disease stages will be crucial to elimination. Modelling can then assist in establishing whether, when, and how the WHO VL elimination targets can be met.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | visceral leishmaniasis; mathematical model; review; Indian subcontinent; kala-azar |
| Subjects: | WA Public Health > WA 105 Epidemiology WA Public Health > Statistics. Surveys > WA 950 Theory or methods of medical statistics. Epidemiologic methods WC Communicable Diseases > Tropical and Parasitic Diseases > WC 715 Visceral leishmaniasis |
| Faculty: Department: | Biological Sciences > Department of Tropical Disease Biology |
| Digital Object Identifer (DOI): | https://doi.org/10.1016/j.pt.2015.03.007 |
| Depositing User: | Mary Creegan |
| Date Deposited: | 17 Dec 2015 09:27 |
| Last Modified: | 25 Jan 2022 10:14 |
| URI: | https://archive.lstmed.ac.uk/id/eprint/5452 |
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