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Association between depression and diabetes amongst adults in Bangladesh: Hospital–based case–control study

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Islam, Sheikh Mohammed Shariful, Ferrari, Uta, Seissler, Jochen, Niessen, Louis ORCID: https://orcid.org/0000-0002-8639-5191 and Lechner, Andreas (2015) 'Association between depression and diabetes amongst adults in Bangladesh: Hospital–based case–control study'. Journal of Global Health, Vol 5, Issue 2.

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Abstract

Methods
A matched case–control study was conducted among 591 consecutive patients with diabetes attending a tertiary hospital in Dhaka and 591 controls matched for age, sex and area of residence without diabetes not related with the index–case. Depression was measured using the Patient Health Questionnaire–9. Multivariate logistic regression was performed to examine the association between depression and diabetes.

Results
The mean age (±standard deviation) of the participants was 50.4±11.4 years, with a male to female ratio of 43:57. The prevalence of depression was 45.2% and 19.8% among cases and controls, respectively. In the multivariate analysis, mild as well as moderate to severe depression were significantly associated with diabetes and independent of sociodemographic factors and co–morbidity (adjusted odds ratio (OR)=2.0, 95% confidence interval (CI)=1.4–2.9 and adjusted OR=6.4, 95% CI=3.4–12.3; P<0.001 for both).

Conclusion
The high prevalence and strong association of depression in individuals with diabetes in Bangladesh suggests that depression should be routinely screened for patients with diabetes at the clinics and that management strategies adequate for resource–poor settings need to be developed. Further research to determine the pathophysiological role of depression in the development of diabetes is merited.

Item Type: Article
Subjects: WA Public Health > Health Problems of Special Population Groups > WA 305 Mental health of special population groups
WA Public Health > Health Problems of Special Population Groups > WA 395 Health in developing countries
WK Endocrine System > WK 810 Diabetes mellitus
WK Endocrine System > WK 835 Complications of diabetes
Faculty: Department: Clinical Sciences & International Health > Clinical Sciences Department
Digital Object Identifer (DOI): https://doi.org/10.7189/jogh.05.020406
Depositing User: Jessica Jones
Date Deposited: 09 Feb 2016 11:29
Last Modified: 06 Feb 2018 13:11
URI: http://archive.lstmed.ac.uk/id/eprint/5494

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