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Flow cytometry to assess CSF fungal burden in cryptococcal meningitis

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Scriven, James, Graham, Lisa M, Schutz, Charlotte, Scriba, Thomas J, Wilkinson, Robert J, Boulware, David R, Meintjes, Graeme, Lalloo, David ORCID: https://orcid.org/0000-0001-7680-2200 and Urban, Britta ORCID: https://orcid.org/0000-0002-4197-8393 (2016) 'Flow cytometry to assess CSF fungal burden in cryptococcal meningitis'. Journal of Clinical Microbiology, Vol 54, Issue 3, pp. 802-804.

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Abstract

Fungal burden in the cerebrospinal fluid is an important determinant of mortality in cryptococcal meningitis but its use to aid clinical decision-making is hampered by the time involved to perform quantitative cultures. Here we demonstrate the potential of flow cytometry as a novel and rapid technique to address this.

Item Type: Article
Subjects: QW Microbiology and Immunology > Fungi. Pathogenic Fungi. > QW 180 Pathogenic Fungi
WC Communicable Diseases > Infection. Bacterial Infections > Bacterial Infections > WC 245 Meningococcal infections
WC Communicable Diseases > Virus Diseases > Acquired Immunodeficiency Syndrome. HIV Infections > WC 503 Acquired immunodeficiency syndrome. HIV infections
WC Communicable Diseases > Virus Diseases > Acquired Immunodeficiency Syndrome. HIV Infections > WC 503.5 Complications
WL Nervous System > WL 200 Meninges. Blood-brain barrier
Faculty: Department: Clinical Sciences & International Health > Clinical Sciences Department
Clinical Sciences & International Health > International Public Health Department
Biological Sciences > Department of Tropical Disease Biology
Digital Object Identifer (DOI): https://doi.org/10.1128/JCM.03002-15
Depositing User: Jessica Jones
Date Deposited: 01 Feb 2016 13:37
Last Modified: 06 Feb 2018 13:11
URI: https://archive.lstmed.ac.uk/id/eprint/5576

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