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Averting a malaria disaster: will insecticide resistance derail malaria control?

Hemingway, Janet ORCID: https://orcid.org/0000-0002-3200-7173, Ranson, Hilary ORCID: https://orcid.org/0000-0003-2332-8247, Magill, Alan, Kolaczinski, Jan, Fornadel, Christen, Gimnig, John, Coetzee, Maureen, Simard, Frederic, Roch, Dabiré K, Hinzoumbe, Clément Kerah, Pickett, John, Schellenberg, David, Hoppé, Mark and Hamon, Nicholas (2016) 'Averting a malaria disaster: will insecticide resistance derail malaria control?'. Lancet, Vol 387, Issue 10029, pp. 1785-1788.

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Abstract

World Malaria Day 2015 highlighted the progress made in the development of new methods of prevention (vaccines and insecticides) and treatment (single dose drugs) of the disease. However, increasing drug and insecticide resistance threatens the successes made with existing methods. Insecticide resistance has decreased the efficacy of the most commonly used insecticide class of pyrethroids. This decreased efficacy has increased mosquito survival, which is a prelude to rising incidence of malaria and fatalities. Despite intensive research efforts, new insecticides will not reach the market for at least 5 years. Elimination of malaria is not possible without effective mosquito control. Therefore, to combat the threat of resistance, key stakeholders need to rapidly embrace a multifaceted approach including a reduction in the cost of bringing new resistance management methods to market and the streamlining of associated development, policy, and implementation pathways to counter this looming public health catastrophe.

Item Type: Article
Subjects: QX Parasitology > Insects. Other Parasites > QX 600 Insect control. Tick control
WA Public Health > Preventive Medicine > WA 240 Disinfection. Disinfestation. Pesticides (including diseases caused by)
WC Communicable Diseases > Tropical and Parasitic Diseases > WC 750 Malaria
WC Communicable Diseases > Tropical and Parasitic Diseases > WC 765 Prevention and control
Faculty: Department: Biological Sciences > Vector Biology Department
Digital Object Identifer (DOI): https://doi.org/10.1016/S0140-6736(15)00417-1
Depositing User: Jessica Jones
Date Deposited: 18 Feb 2016 12:47
Last Modified: 06 Feb 2018 13:11
URI: http://archive.lstmed.ac.uk/id/eprint/5680

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