LSTM Home > LSTM Research > LSTM Online Archive

Physical Activity and Healthy Ageing: A Systematic Review and Meta-analysis of longitudinal cohort studies.

Downloads

Downloads per month over past year

Daskalopoulou, c, Stubbs, B, Kralj, C, Koukounari, Artemis, Prince, M and Prina, A M (2017) 'Physical Activity and Healthy Ageing: A Systematic Review and Meta-analysis of longitudinal cohort studies.'. Ageing Research Reviews, Vol 38, pp. 6-17.

[img]
Preview
Text
AgeingResearchReviews_AK Accepted.pdf - Accepted Version
Available under License Creative Commons Attribution.

Download (789kB) | Preview

Abstract

Older people constitute a significant proportion of the total population and their number is projected to increase by more than half by 2050. This increasing probability of late survival comes with considerable individual, economic and social impact. Physical activity (PA) can influence the ageing process but the specific relationship with healthy ageing (HA) is unclear. We conducted a systematic review and meta-analysis of longitudinal studies examining the associations of PA with HA. Studies were identified from a systematic search across major electronic databases from inception as January 2017. Random-effect meta-analysis was performed to calculate a pooled effect size (ES) and 95% CIs. Studies were assessed for methodological quality. Overall, 23 studies were identified including 174,114 participants (30% men) with age ranges from 20 to 87 years old. There was considerable heterogeneity in the definition and measurement of HA and PA. Most of the identified studies reported a significant positive association of PA with HA, six reported a non-significant. Meta-analysis revealed that PA is positively associated with HA (ES: 1.39, 95% CI=1.23-1.57, n=17) even if adjusted for publication bias (ES: 1.27, 95% CI=1.11-1.45, n=20). There is consistent evidence from longitudinal observational studies that PA is positively associated with HA, regardless of definition and measurement. Future research should focus on the implementation of a single metric of HA, on the use of objective measures for PA assessment and on a full-range of confounding adjustment. In addition, our research indicated the limited research on ageing in low-and-middle income countries. [Abstract copyright: Copyright © 2017. Published by Elsevier B.V.]

Item Type: Article
Subjects: QT Physiology > Human Physiology > QT 104 General works
WA Public Health > WA 20.5 Research (General)
WT Geriatrics. Chronic Disease > Geriatrics > WT 104 Aging process
WT Geriatrics. Chronic Disease > Geriatrics > WT 116 Longevity. Life expectancy. Death
Faculty: Department: Clinical Sciences & International Health > Clinical Sciences Department
Digital Object Identifer (DOI): https://doi.org/10.1016/j.arr.2017.06.003
SWORD Depositor: JISC Pubrouter
Depositing User: Stacy Murtagh
Date Deposited: 11 Jul 2017 10:56
Last Modified: 06 Feb 2018 13:15
URI: http://archive.lstmed.ac.uk/id/eprint/7343

Statistics

View details

Actions (login required)

Edit Item Edit Item