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Modeling host-seeking behavior of African malaria vector mosquitoes in the presence of long-lasting insecticidal nets.

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Shcherbacheva, Anna, Haario, Heikki and Killeen, Gerry (2018) 'Modeling host-seeking behavior of African malaria vector mosquitoes in the presence of long-lasting insecticidal nets.'. Mathematical Biosciences, Vol 295, pp. 36-47.

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Abstract

The efficiency of spatial repellents and long-lasting insecticide-treated nets (LLINs) is a key research topic in malaria control. Insecticidal nets reduce the mosquito-human contact rate and simultaneously decrease mosquito populations. However, LLINs demonstrate dissimilar efficiency against different species of malaria mosquitoes. Various factors have been proposed as an explanation, including differences in insecticide-induced mortality, flight characteristics, or persistence of attack. Here we present a discrete agent-based approach that enables the efficiency of LLINs, baited traps and Insecticide Residual Sprays (IRS) to be examined. The model is calibrated with hut-level experimental data to compare the efficiency of protection against two mosquito species: Anopheles gambiae and Anopheles arabiensis. We show that while such data does not allow an unambiguous identification of the details of how LLINs alter the vector behavior, the model calibrations quantify the overall impact of LLINs for the two different mosquito species. The simulations are generalized to community-scale scenarios that systematically demonstrate the lower efficiency of the LLINs in control of An. Arabiensis compared to An. gambiae. [Abstract copyright: Copyright © 2017. Published by Elsevier Inc.]

Item Type: Article
Subjects: QX Parasitology > Insects. Other Parasites > QX 510 Mosquitoes
QX Parasitology > Insects. Other Parasites > QX 600 Insect control. Tick control
WA Public Health > Preventive Medicine > WA 240 Disinfection. Disinfestation. Pesticides (including diseases caused by)
WA Public Health > Health Problems of Special Population Groups > WA 395 Health in developing countries
WC Communicable Diseases > Tropical and Parasitic Diseases > WC 750 Malaria
WC Communicable Diseases > Tropical and Parasitic Diseases > WC 765 Prevention and control
Faculty: Department: Biological Sciences > Vector Biology Department
Digital Object Identifer (DOI): https://doi.org/10.1016/j.mbs.2017.10.005
SWORD Depositor: JISC Pubrouter
Depositing User: JISC Pubrouter
Date Deposited: 27 Oct 2017 10:33
Last Modified: 13 Apr 2018 09:12
URI: http://archive.lstmed.ac.uk/id/eprint/7761

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