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Protocol of economic evaluation and equity impact analysis of mHealth and community groups for prevention and control of diabetes in rural Bangladesh in a three-arm cluster randomised controlled trial

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Haghparast-Bidgoli, Hassan, Kumar Shaha, Sanjit, Kuddus, Abdul, Chowdhury, Alimul Reza, Jennings, Hannah, Ahmed, Naveed, Morrison, Joanna, Akter, Kohenour, Nahar, Badrun, Nahar, Tasmin, King, Carina, Skordis, Jolene, Batura, Neha, Khan, Jahangir, Mansaray, Anthony, Hunter, Rachael, Khan, A.K. Azad, Costello, Anthony, Azad, Kishwar and Fottrell, Edward (2018) 'Protocol of economic evaluation and equity impact analysis of mHealth and community groups for prevention and control of diabetes in rural Bangladesh in a three-arm cluster randomised controlled trial'. BMJ Open, Vol 8, e022035.

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Abstract

Introduction: Type 2 Diabetes mellitus (T2DM) is one of the leading causes of death and disability worldwide, generating substantial economic burden for people with diabetes and their families, and to health systems and national economies. Bangladesh has one of the largest numbers of adults with diabetes in the South Asian region. This paper describes the planned economic evaluation and equity impact analysis of a three-arm cluster randomised control trial of mHealth and community mobilisation interventions to prevent and control T2DM and non-communicable diseases’ (NCDs) risk factors in rural Bangladesh (D-Magic trial).

Methods and Analysis: The economic evaluation will be conducted as a within-trial analysis to evaluate the incremental costs and health outcomes of mHealth and community mobilisation interventions compared to the status quo. The analyses will be conducted from a societal perspective, assessing the economic impact for all parties affected by the interventions, including implementing agencies (program costs), health care providers, and participants and their households. Incremental cost-effectiveness ratios (ICERs) will be calculated in terms of cost per case of intermediate hyperglycaemia and T2DM prevented and cost per case of diabetes prevented among individuals with intermediate hyperglycaemia at baseline, and cost- per mm Hg reduction in systolic blood pressure. In addition to ICERs, the economic evaluation will be presented as a cost-consequence analysis where the incremental costs and all statistically significant outcomes will be listed separately. Robustness of the results will be assessed through sensitivity analyses. In addition to cost-effectiveness analysis, an analysis of equity impact of the interventions among the target population will be conducted.

Ethics and dissemination: The approval to conduct the study was obtained by the University College London Research Ethics Committee (4766/002) and by the Ethical Review Committee of the Diabetic Association of Bangladesh (BADAS-ERC/EC/t5100246). The findings of this study will be disseminated through different means within academia and the wider policy sphere.

Item Type: Article
Subjects: W General Medicine. Health Professions > W 74 Medical economics. Health care costs
W General Medicine. Health Professions > W 21.5 Allied health personnel. Allied health professions
W General Medicine. Health Professions > Health Services. Patients and Patient Advocacy > W 84 Health services. Delivery of health care
WA Public Health > WA 30 Socioeconomic factors in public health (General)
WA Public Health > Health Problems of Special Population Groups > WA 395 Health in developing countries
WK Endocrine System > WK 810 Diabetes mellitus
Faculty: Department: Clinical Sciences & International Health > Clinical Sciences Department
Digital Object Identifer (DOI): https://doi.org/10.1136/bmjopen-2018-022035
Depositing User: Stacy Murtagh
Date Deposited: 24 Aug 2018 08:13
Last Modified: 07 Sep 2018 12:34
URI: http://archive.lstmed.ac.uk/id/eprint/8968

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