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The Cooking and Pneumonia Study (CAPS) in Malawi: A Cross-Sectional Assessment of Carbon Monoxide Exposure and Carboxyhemoglobin Levels in Children under 5 Years Old.

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Havens, Deborah, Wang, Duolao ORCID: https://orcid.org/0000-0003-2788-2464, Grigg, Jonathan, Gordon, Stephen ORCID: https://orcid.org/0000-0001-6576-1116, Balmes, John and Mortimer, Kevin ORCID: https://orcid.org/0000-0002-8118-8871 (2018) 'The Cooking and Pneumonia Study (CAPS) in Malawi: A Cross-Sectional Assessment of Carbon Monoxide Exposure and Carboxyhemoglobin Levels in Children under 5 Years Old.'. International Journal of Environmental Research and Public Health, Vol 15, Issue 9, p. 1936.

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Abstract

Household air pollution is estimated to cause half a million deaths from pneumonia in children worldwide. The Cooking and Pneumonia Study (CAPS) was conducted to determine whether the use of cleaner-burning biomass-fueled cookstoves would reduce household air pollution and thereby the incidence of pneumonia in young children in rural Malawi. Here we report a cross-sectional assessment of carbon monoxide (CO) exposure and carboxyhemoglobin (COHgB) levels at recruitment to CAPS. Mean (SD; range) 48-h CO exposure of 1928 participating children was 0.90 (2.3; 0⁻49) ppm and mean (SD; range) COHgB level was 5.8% (3.3; 0⁻20.3). Higher mean CO and COHgB levels were associated with location (Chikhwawa versus Chilumba) (OR 3.55 (1.73⁻7.26)); (OR 2.77 (1.08⁻7.08)). Correlation between mean CO and COHgB was poor (Spearman's ρ = 0.09, < 0.001). The finding of high COHgB levels in young children in rural Malawi that are at levels at which adverse neurodevelopmental and cognitive effects occur is of concern. Effective approaches for reducing exposure to CO and other constituents of air pollution in rural sub-Saharan African settings are urgently needed.

Item Type: Article
Subjects: WA Public Health > Air pollution > WA 750 Air sanitation and hygiene
WA Public Health > Air pollution > WA 754 Pollution and pollutants (incl. tobacco pollution; passive smoking)
WC Communicable Diseases > Infection. Bacterial Infections > Bacterial Infections > WC 202 Pneumonia (General or not elsewhere classified)
WF Respiratory System > WF 20 Research (General)
WS Pediatrics > Child Care. Nutrition. Physical Examination > WS 141 Physical examination. Diagnosis. Mass screening. Monitoring
WS Pediatrics > WS 20 Research (General)
Faculty: Department: Clinical Sciences & International Health > Clinical Sciences Department
Clinical Sciences & International Health > Malawi-Liverpool-Wellcome Programme (MLW)
Digital Object Identifer (DOI): https://doi.org/10.3390/ijerph15091936
Depositing User: Stacy Murtagh
Date Deposited: 13 Sep 2018 15:15
Last Modified: 07 Oct 2019 08:24
URI: https://archive.lstmed.ac.uk/id/eprint/9292

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