Air Pollution and Non-Communicable Diseases: A Review by the Forum of International Respiratory Societies' Environmental Committee, Part 1: The damaging effects of air pollution.

Schraufnagel, Dean E, Balmes, John, Cowl, Clayton T, De Matteis, Sara, Jung, Soon-Hee, Mortimer, Kevin ORCID: https://orcid.org/0000-0002-8118-8871, Perez-Padilla, Rogelio, Rice, Mary B, Riojas-Rodroguez, Horacio, Sood, Akshay, Thurston, George D, To, Teresa, Vanker, Anessa and Wuebbles, Donald J (2019) 'Air Pollution and Non-Communicable Diseases: A Review by the Forum of International Respiratory Societies' Environmental Committee, Part 1: The damaging effects of air pollution.'. Chest, Vol 155, Issue 2, pp. 409-416.

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Abstract

Air pollution poses a great environmental risk to health. Outdoor fine particulate matter (PM) exposure is the fifth leading risk factor for death in the world, accounting for 4.2 million deaths and more than a hundred million disability-adjusted-life-years lost according to the Global Burden of Disease Report. The World Health Organization attributes 3.8 million additional deaths to Indoor air pollution. Air pollution can harm acutely, usually manifested by respiratory or cardiac symptoms, as well as chronically, potentially affecting every organ in the body. It can cause, complicate, or exacerbate many adverse health conditions. Tissue damage may result directly from pollutant toxicity, because fine and ultrafine particles can gain access to organs, or indirectly through systemic inflammatory processes. Susceptibility is partly under genetic and epigenetic regulation. Although air pollution affects people of all regions, ages, and social groups, it is likely to cause greater illness in those with heavy exposure and greater susceptibility. Persons are more vulnerable to air pollution if they have other illnesses or less social support. Harmful effects occur on a continuum of dosage and even at levels below air quality standards previously considered to be safe.

Item Type:	Article
Subjects:	WA Public Health > Air pollution > WA 750 Air sanitation and hygiene WA Public Health > Air pollution > WA 754 Pollution and pollutants (incl. tobacco pollution; passive smoking) WF Respiratory System > WF 140 Diseases of the respiratory system (General) WF Respiratory System > WF 20 Research (General) WF Respiratory System > Lungs > WF 600 Lungs
Faculty: Department:	Clinical Sciences & International Health > Clinical Sciences Department
Digital Object Identifer (DOI):	https://doi.org/10.1016/j.chest.2018.10.042
Depositing User:	Stacy Murtagh
Date Deposited:	27 Nov 2018 11:42
Last Modified:	09 Nov 2019 02:02
URI:	https://archive.lstmed.ac.uk/id/eprint/9695

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