Items where LSTM Author is "Ward, Steve"

Article

Hegde, ShrilakshmI, Marriott, Amy, Pionnier, Nicolas ORCID: https://orcid.org/0000-0002-2379-4945, Steven, Andrew, Bulman, Christina, Gunderson, Emma, Vogel, Ian, Koschel, Marianne, Ehrens, Alexandra, Lustigman, Sara, Voronin, Denis, Tricoche, Nancy, Hoerauf, Achim, Hübner, Marc P., Sakanari, Judy, Aljayyoussi, Ghaith, Gusovsky, Fabian, Dagley, Jessica, Hong, David W., O'Neill, Paul, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 and Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476 (2024) 'Combinations of the azaquinazoline anti-Wolbachia agent, AWZ1066S, with benzimidazole anthelmintics synergise to mediate sub-seven-day sterilising and curative efficacies in experimental models of filariasis'. Frontiers in Microbiology, Vol 15, p. 1346068. (In Press)

Lisauskaitė, Monika, Nixon, Gemma L., Woodley, Christopher M., Berry, Neil G., Coninckx, Andy, Qie, L. Charlie, Leung, Suet C., Taramelli, Donatella, Basilico, Nicoletta, Parapini, Silvia, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Vadas, Oscar, Soldati-Favre, Dominique, Hong, W. David and O'Neill, Paul M. (2023) 'Design, synthesis and modelling of photoreactive chemical probes for investigating target engagement of plasmepsin IX and X in Plasmodium falciparum'. RSC Chemical Biology, Vol 5, Issue 1, pp. 19-29.

Jeffreys, Laura ORCID: https://orcid.org/0000-0002-0607-6116, Ardrey, Alison, Hafiz, Taghreed, Dyer, Lauri-Anne, Warman, Ashley, Mosallam, Nada, Nixon, Gemma, Fisher, Nicholas, Hong, W. David, Leung, Suet C., Aljayyoussi, Ghaith, Bibby, Jaclyn, Almeida, Deepak V., Converse, Paul J., Fotouhi, Nader, Berry, Neil G., Nuermberger, Eric L., Upton, Anna M., O’Neill, Paul M., Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2023) 'Identification of 2-Aryl-Quinolone Inhibitors of Cytochrome bd and Chemical Validation of Combination Strategies for Respiratory Inhibitors against Mycobacterium tuberculosis'. ACS Infectious Diseases, Vol 9, Issue 2, pp. 221-238.

Donnellan, Samantha, Pennington, Shaun ORCID: https://orcid.org/0000-0002-7160-6275, Ruggiero, Alessandra, Martinez-Rodriguez, Carmen, Pouget, Marion, Thomas, Jordan, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Pollakis, Georgios, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and Paxton, William (2022) 'A quantitative method for the study of HIV-1 and Mycobacterium tuberculosis co-infection'. Journal of Infectious Disease, Vol 227, Issue 5, pp. 708-713.

Mandala, Wilson L., Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Taylor, Terrie E. and Wassmer, Samuel C. (2022) 'Characterization of Lymphocyte Subsets in Lymph Node and Spleen Sections in Fatal Pediatric Malaria'. Pathogens, Vol 11, Issue 8, e851.

Amporndanai, Kangsa, Pinthong, Nattapon, O’Neill, Paul M., Hong, W. David, Amewu, Richard K., Pidathala, Chandrakala, Berry, Neil G., Leung, Suet C., Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Hasnain, S. Samar and Antonyuk, Svetlana V. (2022) 'Targeting the Ubiquinol-Reduction (Qi) Site of the Mitochondrial Cytochrome bc1 Complex for the Development of Next Generation Quinolone Antimalarials'. Biology, Vol 11, Issue 8, e1109.

Quek, Shannon ORCID: https://orcid.org/0000-0002-1583-9541, Cook, Darren, Wu, Yang, Marriott, Amy, Steven, Andrew, Johnston, Kelly, Ford, Louise, Archer, John, Hemingway, Janet ORCID: https://orcid.org/0000-0002-3200-7173, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Wagstaff, Simon ORCID: https://orcid.org/0000-0003-0577-5537, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476 and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2022) 'Wolbachia depletion blocks transmission of lymphatic filariasis by preventing chitinase-dependent parasite exsheathment'. Proceedings of the National Academy of Sciences, Vol 119, Issue 15, e2120003119.

Mansoor, Rashid, Commons, Robert J., Douglas, Nicholas M., Abuaku, Benjamin, Achan, Jane, Adam, Ishag, Adjei, George O., Adjuik, Martin, Alemayehu, Bereket H., Allan, Richard, Allen, Elizabeth N., Anvikar, Anupkumar R., Arinaitwe, Emmanuel, Ashley, Elizabeth A., Ashurst, Hazel, Asih, Puji B. S., Bakyaita, Nathan, Barennes, Hubert, Barnes, Karen I., Basco, Leonardo, Bassat, Quique, Baudin, Elisabeth, Bell, David J, Bethell, Delia, Bjorkman, Anders, Boulton, Caroline, Bousema, Teun, Brasseur, Philippe, Bukirwa, Hasifa, Burrow, Rebekah, Carrara, Verena I., Cot, Michel, D’Alessandro, Umberto, Das, Debashish, Das, Sabyasachi, Davis, Timothy M. E., Desai, Meghna, Djimde, Abdoulaye A., Dondorp, Arjen M., Dorsey, Grant, Drakeley, Chris J., Duparc, Stephan, Espié, Emmanuelle, Etard, Jean-Francois, Falade, Catherine, Faucher, Jean Francois, Filler, Scott, Fogg, Carole, Fukuda, Mark, Gaye, Oumar, Genton, Blaise, Ghulam Rahim, Awab, Gilayeneh, Julius, Gonzalez, Raquel, Grais, Rebecca F., Grandesso, Francesco, Greenwood, Brian, Grivoyannis, Anastasia, Hatz, Christoph, Hodel, Eva Maria, Humphreys, Georgina S., Hwang, Jimee, Ishengoma, Deus, Juma, Elizabeth, Kachur, S. Patrick, Kager, Piet A., Kamugisha, Erasmus, Kamya, Moses R., Karema, Corine, Kayentao, Kassoum, Kazienga, Adama, Kiechel, Jean-René, Kofoed, Poul-Erik, Koram, Kwadwo, Kremsner, Peter G., Lalloo, David G., Laman, Moses, Lee, Sue J., Lell, Bertrand, Maiga, Amelia W., Mårtensson, Andreas, Mayxay, Mayfong, Mbacham, Wilfred, McGready, Rose, Menan, Hervé, Ménard, Didier, Mockenhaupt, Frank, Moore, Brioni R., Müller, Olaf, Nahum, Alain, Ndiaye, Jean-Louis, Newton, Paul N., Ngasala, Billy E., Nikiema, Frederic, Nji, Akindeh M., Noedl, Harald, Nosten, Francois, Ogutu, Bernhards R., Ojurongbe, Olusola, Osorio, Lyda, Ouédraogo, Jean-Bosco, Owusu-Agyei, Seth, Pareek, Anil, Penali, Louis K., Piola, Patrice, Plucinski, Mateusz, Premji, Zul, Ramharter, Michael, Richmond, Caitlin L., Rombo, Lars, Roper, Cally, Rosenthal, Philip J., Salman, Sam, Same-Ekobo, Albert, Sibley, Carol, Sirima, Sodiomon B., Smithuis, Frank M., Somé, Fabrice A., Staedke, Sarah G., Starzengruber, Peter, Strub-Wourgaft, Nathalie, Sutanto, Inge, Swarthout, Todd D., Syafruddin, Din, Talisuna, Ambrose O., Taylor, Walter R., Temu, Emmanuel A., Thwing, Julie I., Tinto, Halidou, Tjitra, Emiliana, Touré, Offianan A., Tran, T. Hien, Ursing, Johan, Valea, Innocent, Valentini, Giovanni, van Vugt, Michele, von Seidlein, Lorenz, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Were, Vincent, White, Nicholas J., Woodrow, Charles J., Yavo, William, Yeka, Adoke, Zongo, Issaka, Simpson, Julie A., Guerin, Philippe J., Stepniewska, Kasia and Price, Ric N. (2022) 'Haematological consequences of acute uncomplicated falciparum malaria: a WorldWide Antimalarial Resistance Network pooled analysis of individual patient data'. BMC Medicine, Vol 20, Issue 1, e85.

Jeffreys, Laura ORCID: https://orcid.org/0000-0002-0607-6116, Pennington, Shaun ORCID: https://orcid.org/0000-0002-7160-6275, Duggan, Jack, Caygill, Claire, Lopeman, Rose, Breen, Alastair, Jinks, Jessica, Ardrey, Alison, Donnellan, Samantha, Patterson, Ian ORCID: https://orcid.org/0000-0003-3465-0848, Hughes, Grant ORCID: https://orcid.org/0000-0002-7567-7185, Hong, David W, O'Neill, Paul M, Aljayyoussi, Ghaith, Owen, Andrew, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2022) 'Remdesivir-ivermectin combination displays synergistic interaction with improved in vitro activity against SARS-CoV-2'. International Journal of Antimicrobial Agents, Vol 59, Issue 3, e106542.

Johnston, Kelly, Hong, W. David, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, O’Neill, Paul M., Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2021) 'Anti-Wolbachia drugs for filariasis'. Trends in Parasitology, Vol 37, Issue 12, pp. 1068-1081.

McGillan, Paul, Berry, Neil G., Nixon, Gemma L., Leung, Suet C., Webborn, Peter J. H., Wenlock, Mark C., Kavanagh, Stefan, Cassidy, Andrew, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cook, Darren, Johnston, Kelly, Ford, Louise, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, Hong, David and O’Neill, Paul M. (2021) 'Development of Pyrazolopyrimidine Anti-Wolbachia Agents for the Treatment of Filariasis'. ACS Medicinal Chemistry Letters, Vol 12, Issue 9, pp. 1421-1426.

Woodley, Christopher M., Nixon, Gemma L., Basilico, Nicoletta, Parapini, Silvia, Hong, Weiqian David, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Leung, Suet C., Taramelli, Donatella, Onuma, Keiko, Hasebe, Takashi and O’Neill, Paul M. (2021) 'Enantioselective Synthesis and Profiling of Potent, Nonlinear Analogues of Antimalarial Tetraoxanes E209 and N205'. ACS Medicinal Chemistry Letters, Vol 12, Issue 7, pp. 1077-1085.

Stachulski, Andrew V., Taujanskas, Joshua, Pate, Sophie L., Rajoli, Rajith K. R., Aljayyoussi, Ghaith, Pennington, Shaun H. ORCID: https://orcid.org/0000-0002-7160-6275, Ward, Stephen A. ORCID: https://orcid.org/0000-0003-2331-3192, Hong, Weiqian David, Biagini, Giancarlo A. ORCID: https://orcid.org/0000-0001-6356-6595, Owen, Andrew, Nixon, Gemma L., Leung, Suet C. and O’Neill, Paul M. (2021) 'Therapeutic Potential of Nitazoxanide: An Appropriate Choice for Repurposing versus SARS-CoV-2?'. ACS Infectious Diseases, Vol 7, Issue 6, pp. 1317-1331.

Rajoli, Rajith K.R., Pertinez, Henry, Arshad, Usman, Box, Helen, Tatham, Lee, Curley, Paul, Neary, Megan, Sharp, Joanne, Liptrott, Neill J., Valentijn, Anthony, David, Christopher, Rannard, Steven P., Aljayyoussi, Ghaith, Pennington, Shaun ORCID: https://orcid.org/0000-0002-7160-6275, Hill, Andrew, Boffito, Marta, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Khoo, Saye, Bray, Patrick G., O'Neill, Paul M., Hong, W. David, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and Owen, Andrew (2021) 'Dose Prediction for Repurposing Nitazoxanide in SARS‐CoV‐2 Treatment or Chemoprophylaxis'. British Journal of Clinical Pharmacology, Vol 87, Issue 4, pp. 2078-2088.

Arshad, Usman, Pertinez, Henry, Box, Helen, Tatham, Lee, Rajoli, Rajith KR, Curley, Paul, Neary, Megan, Sharp, Joanne, Liptrott, Neill J, Valentijn, Anthony, David, Christopher, Rannard, Steve P, O’Neill, Paul M, Aljayyoussi, Ghaith, Pennington, Shaun ORCID: https://orcid.org/0000-0002-7160-6275, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Hill, Andrew, Back, David J, Khoo, Saye H, Bray, Patrick G, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and Owen, Andrew (2020) 'Prioritisation of Anti‐SARS‐Cov‐2 Drug Repurposing Opportunities Based on Plasma and Target Site Concentrations Derived from their Established Human Pharmacokinetics'. Clinical Pharmacology and Therapeutics, Vol 108, Issue 4, pp. 775-790.

Kloprogge, Frank, Mwandumba, Henry ORCID: https://orcid.org/0000-0003-4470-3608, Banda, Gertrude, Kamdolozi, Mercy, Shani, Doris, Corbett, Elizabeth L, Kontogianni, Nadia, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Khoo, Saye H, Davies, Geraint R and Sloan, Derek (2020) 'Longitudinal PKPD biomarkers correlate with treatment outcome in drug sensitive pulmonary tuberculosis; a population pharmacokinetic-pharmacodynamic analysis'. Open Forum Infectious Diseases, Vol 7, Issue 7, ofaa218.

Yu, Pan, Yang, Jia-Ning, Yan, Jin-Wu, Meng, Zhi-Zhong, Hong, David, Roberts, Adam P. ORCID: https://orcid.org/0000-0002-0760-3088, Ward, Stephen A. ORCID: https://orcid.org/0000-0003-2331-3192, Zhang, Lei and Li, Shan (2020) 'A novel fluorescent probe for the detection of AmpC beta-lactamase and the application in screening beta-lactamase inhibitors'. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, Vol 234, e118257.

Klinkhamhom, Aekkarin, Glaharn, Supattra, Srisook, Charit, Ampawong, Sumate, Krudsood, Srivicha, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Viriyavejakul, Parnpen (2020) 'M1 macrophage features in severe Plasmodium falciparum malaria patients with pulmonary oedema'. Malaria Journal, Vol 19, Issue 182.

Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Marriott, Amy, Hong, David, O’ Neill, Paul, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2020) 'Novel anti-Wolbachia drugs, a new approach in the treatment and prevention of veterinary filariasis?'. Veterinary Parasitology, Vol 279, p. 109057.

Scott, Janet T, Sharma, Raman, Meredith, Luke W, Dunning, Jake, Moore, Catrin E, Sahr, Foday, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Goodfellow, Ian and Horby, Peter (2020) 'Pharmacokinetics of TKM-130803 in Sierra Leonean patients with Ebola virus disease:  plasma concentrations exceed target levels, with drug accumulation in the most severe patients.'. EBioMedicine, Vol 52, e102601.

Ehrens, Alexandra, Lunde, Christopher S, Jacobs, Robert T, Struever, Dominique, Koschel, Marianne, Frohberger, Stefan J, Lenz, Franziska, Fendler, Martina, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, Freund, Yvonne R, Stefanakis, Rianna, Easom, Eric, Li, Xianfeng, Plattner, Jacob J, Hoerauf, Achim and Hübner, Marc P. (2020) 'In vivo efficacy of the boron-pleuromutilin AN11251 against Wolbachia of the rodent filarial nematode Litomosoides sigmodontis'. PLoS Neglected Tropical Diseases, Vol 14, Issue 1, e0007957.

Nkhom, Standwell C., Trevino, Simon G., Gorena, Karla M., Nair, Shalini, Khosw, Stanley, Jett, Catherine, Garcia, Roy, Daniel, Benjamin, Dia, Aliou, Terlouw, Dianne ORCID: https://orcid.org/0000-0001-5327-8995, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Anderson, Timothy J.C. and Cheeseman, Ian H. (2020) 'Co-transmission of related parasite lineages shapes within-host parasite diversity'. Cell Host & Microbe, Vol 27, Issue 1, 93-103.e4.

Donnellan, Samantha, Aljayyoussi, Ghaith, Moyo, Emmanuel, Ardrey, Alison, Martinez-Rodriguez, Carmen, Ward, Stephen A ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo A ORCID: https://orcid.org/0000-0001-6356-6595 (2019) 'Intracellular pharmacodynamic modelling (PDi) is predictive of the clinical activity of fluoroquinolones against Tuberculosis'. Antimicrobial Agents and Chemotherapy, Vol 64, e00989-19.

Smit, Menno ORCID: https://orcid.org/0000-0003-3405-6638, Ochomo, Eric O, Aljayyoussi, Ghaith, Kwambai, Titus, Abong’o, Bernard O, Bousema, Teun, Waterhouse, David, Bayoh, Nabie M, Gimnig, John E, Samuels, Aaron M, Desai, Meghna R, Phillips-Howard, Penelope ORCID: https://orcid.org/0000-0003-1018-116X, Kariuki, Simon K, Wang, Duolao ORCID: https://orcid.org/0000-0003-2788-2464, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and terKuile, Feiko ORCID: https://orcid.org/0000-0003-3663-5617 (2019) 'Human Direct Skin Feeding versus Membrane Feeding to Assess the Mosquitocidal Efficacy of High-Dose Ivermectin (IVERMAL Trial)'. Clinical Infectious Diseases, Vol 69, Issue 7, pp. 1112-1119.

Hübner, Marc P., Koschel, Marianne, Struever, Dominique, Nikolov, Venelin, Frohberger, Stefan J., Ehrens, Alexandra, Fendler, Martina, Johannes, Iliana, von Geldern, Thomas W., Marsh, Kennan, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Pfarr, Kenneth, Kempf, Dale J. and Hoerauf, Achim (2019) 'In vivo kinetics of Wolbachia depletion by ABBV-4083 in L. sigmodontis adult worms and microfilariae'. PLoS Neglected Tropical Diseases, Vol 13, Issue 8, e0007636.

Camarda, Grazia, Jirawatcharadech, Piyaporn, Priestley, Richard, Saif, Ahmed, March, Sandra, Wong, Michael H. L., Leung, Suet, Miller, Alex, Baker, David A., Alano, Pietro, Paine, Mark ORCID: https://orcid.org/0000-0003-2061-7713, Bhatia, Sangeeta N., O'Neill, Paul M., Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2019) 'Antimalarial activity of primaquine operates via a two-step biochemical relay'. Nature Communications, Vol 10, p. 3226.

Aljayyoussi, Ghaith, Donnellan, Samantha, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2019) 'Intracellular PD Modelling (PDi) for the Prediction of Clinical Activity of Increased Rifampicin Dosing'. Pharmaceutics, Vol 11, Issue 6, p. 278.

Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Clark, Roger, Bardelle, Catherine, Harper, Paul, Collier, Matthew, Johnston, Kelly, Plant, Helen, Plant, Darren, McCall, Eileen, Slatko, Barton E., Cantin, Lindsey, Wu, Bo, Ford, Louise, Murray, David, Rich, Kirsty, Wigglesworth, Mark, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2019) 'Development of a High-Throughput Cytometric Screen to Identify Anti-Wolbachia Compounds: The Power of Public–Private Partnership'. SLAS Discovery, Vol 24, Issue 5, pp. 537-547.

Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, von Geldern, Thomas W, Ford, Louise, Hübner, Marc P, Marsh, Kennan, Johnston, Kelly, Sjoberg, Hanna, Specht, Sabine, Pionnier, Nicolas ORCID: https://orcid.org/0000-0002-2379-4945, Tyrer, Hayley, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cook, Darren, Murphy, Emma ORCID: https://orcid.org/0000-0001-9421-7777, Steven, Andrew, Archer, John, Bloemker, Dominique, Lenz, Franziska, Koschel, Marianne, Ehrens, Alexandra, Metuge, Haelly M, Chunda, Valerinne C, Ndongmo Chounna, Patrick W, Njouendou, Abdel J, Fombad, Fanny F, Carr, Robert, Morton, Howard E, Aljayyoussi, Ghaith, Hoerauf, Achim, Wanji, Samuel, Kempf, Dale J, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476 and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2019) 'Preclinical development of an oral anti-Wolbachia macrolide drug for the treatment of lymphatic filariasis and onchocerciasis'. Science Translational Medicine, Vol 11, Issue 483.

Birgersson, Sofia, Valea, Innocent, Tinto, Halidou, Traore-Coulibaly, Maminata, Toe, Laeticia C., Hoglund, Richard M., Van Geertruyden, Jean-Pierre, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, D’Alessandro, Umberto, Abelö, Angela and Tarning, Joel (2019) 'Population pharmacokinetics of artesunate and dihydroartemisinin in pregnant and non-pregnant women with uncomplicated Plasmodium falciparum malaria in Burkina Faso: an open label trial'. Wellcome Open Research, Vol 4, p. 45.

von Geldern, Thomas W, Morton, Howard E, Clark, Rick F, Brown, Brian S, Johnston, Kelly, Ford, Louise, Specht, Sabine, Carr, Robert A, Stolarik, Deanne F, Ma, Junli, Rieser, Matthew J, Struever, Dominique, Frohberger, Stefan J, Koschel, Marianne, Ehrens, Alexandra, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Hübner, Marc P, Hoerauf, Achim, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Marsh, Kennan and Kempf, Dale J (2019) 'Discovery of ABBV-4083, a novel analog of Tylosin A that has potent anti-Wolbachia and anti-filarial activity.'. PLoS Neglected Tropical Diseases, Vol 13, Issue 2, e0007159.

Jacobs, Robert Toms, Lunde, Christopher S, Freund, Yvonne R, Hernandez, Vincent, Li, Xianfeng, Xia, Yi, Carter, David S, Berry, Pamela, Halladay, Jason, Rock, Fernando, Stefanakis, Rianna, Easom, Eric E, Plattner, Jacob J, Ford, Louise, Johnston, Kelly L, Cook, Darren A N, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cassidy, Andrew, Myhill, Laura, Tyrer, Hayley, Gamble, Joanne, Guimaraes, Ana F, Steven, Andrew, Lenz, Franziska, Ehrens, Alexandra, Frohberger, Stefan J, Koschel, Marianne, Hoerauf, Achim, Hübner, Marc P, McNamara, Case, Bakowski, Malina A, Turner, Joseph D ORCID: https://orcid.org/0000-0002-2185-5476, Taylor, Mark J ORCID: https://orcid.org/0000-0003-3396-9275 and Ward, Stephen A ORCID: https://orcid.org/0000-0003-2331-3192 (2019) 'Boron-Pleuromutilins as Anti-Wolbachia Agents with Potential for Treatment of Onchocerciasis and Lymphatic Filariasis.'. Journal of medicinal chemistry.

Requena-Méndez, Ana, Davies, Geraint, Waterhouse, David, Ardrey, Alison, Jave, Oswaldo, López-Romero, Sonia Llanet, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Moore, David A J (2019) 'Intra-individual effects of food upon the pharmacokinetics of rifampicin and isoniazid.'. The Journal of Antimicrobial Chemotherapy, Vol 74, Issue 2, pp. 416-424.

Smit, Menno ORCID: https://orcid.org/0000-0003-3405-6638, Ochomo, Eric O, Waterhouse, David, Kwambai, Titus K, Abong'o, Bernard O, Bousema, Teun, Bayoh, Nabie M, Gimnig, John E, Samuels, Aaron M, Desai, Meghna R, Phillips-Howard, Penelope ORCID: https://orcid.org/0000-0003-1018-116X, Kariuki, Simon K, Wang, Duolao ORCID: https://orcid.org/0000-0003-2788-2464, terKuile, Feiko ORCID: https://orcid.org/0000-0003-3663-5617, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Aljayyoussi, Ghaith (2019) 'Pharmacokinetics-Pharmacodynamics of High-Dose Ivermectin with Dihydroartemisinin-Piperaquine on Mosquitocidal Activity and QT-prolongation (IVERMAL)'. Clinical Pharmacology and Therapeutics, Vol 105, Issue 2, pp. 388-401.

Hong, W David, Benayoud, Farid, Nixon, Gemma L, Ford, Louise, Johnston, Kelly, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cassidy, Andrew, Cook, Darren A N, Siu, Amy, Shiotani, Motohiro, Webborn, Peter J H, Kavanagh, Stefan, Aljayyoussi, Ghaith, Murphy, Emma, Steven, Andrew, Archer, John, Struever, Dominique, Frohberger, Stefan J, Ehrens, Alexandra, Hübner, Marc P, Hoerauf, Achim, Roberts, Adam ORCID: https://orcid.org/0000-0002-0760-3088, Hubbard, Alasdair ORCID: https://orcid.org/0000-0001-6668-9179, Tate, Edward W, Serwa, Remigiusz A, Leung, Suet C, Qie, Li, Berry, Neil G, Gusovsky, Fabian, Hemingway, Janet, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and O'Neill, Paul M (2019) 'AWZ1066S, a highly specific anti- drug candidate for a short-course treatment of filariasis.'. Proceedings of the National Academy of Sciences of the United States of America, Vol 116, Issue 4, pp. 1414-1419.

Sjoberg, Hanna ORCID: https://orcid.org/0000-0003-1948-6779, Pionnier, Nicolas ORCID: https://orcid.org/0000-0002-2379-4945, Aljayyoussi, Ghaith, Metuge, Haelly, Njouendou, Abdel, Chunda, Valerine C., Fombad, Fanny F., Tayong, Dizzle B., Gandjui, Narcisse V. T., Akumtoh, Desmond N., Chounna, Patrick W. N., Ndzeshang, Bertrand L., Lachaud, Sophie, Tekle, Fetene, Quirynen, Ludo, Engelen, Marc, Baeten, Benny, Steven, Andrew, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, Wanji, Samuel and Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476 (2019) 'Short-course, oral flubendazole does not mediate significant efficacy against Onchocerca adult male worms or Brugia microfilariae in murine infection models'. PLoS Neglected Tropical Diseases, Vol 13, Issue 1, e0006356.

Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Bardelle, Catherine, Harper, Paul, Hong, Weiqian, Borjesson, Ulf, Johnston, Kelly, Collier, Matthew, Myhill, Laura, Cassidy, Andrew, Plant, Darren, Plant, Helen, Clark, Roger, Cook, Darren, Steven, Andrew, Archer, John, McGillan, Paul, Charoensutthivarakul, Sitthivut, Bibby, Jaclyn, Sharma, Raman, Nixon, Gemma, Slatko, Barton, Cantin, Lindsey, Wu, Bo, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Ford, Louise, Rich, Kirsty, Wigglesworth, Mark, Berry, Neil, O'Neill, Paul, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2019) 'Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides'. Nature Communications, Vol 10, Issue 11.

Nkhoma, Standwell, Banda, Rachel, Khoswe, Stanley, Dzoole-Mwale, Tamika and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2018) 'Intra-host dynamics of co-infecting parasite genotypes in asymptomatic malaria patients.'. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, Vol 65, pp. 414-424.

Wu, Pan-Pan, He, Hao, Hong, W David, Wu, Tong-Rong, Huang, Gui-Ying, Zhong, Ying-Ying, Tu, Bo-Rong, Gao, Min, Zhou, Jun, Zhao, Su-Qing, Li, Dong-Li, Xu, Xue-Tao, Sheng, Zhao-Jun, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, O'Neill, Paul M and Zhang, Kun (2018) 'The biological evaluation of fusidic acid and its hydrogenation derivative as antimicrobial and anti-inflammatory agents.'. Infection and Drug Resistance, Vol 11, pp. 1945-1957.

Hong, David, Leung, S, Amporndanai, Kangsa, Davies, Jill, Priestley, Richard, Nixon, Gemma L., Berry, Neil G., Samar Hasnain, S., Antonyuk, Svetlana, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and O’Neill, Paul M. (2018) 'Potent Antimalarial 2-Pyrazolyl Quinolone bc1 (Qi) Inhibitors with Improved Drug-like Properties'. ACS Medicinal Chemistry Letters, Vol 9, Issue 12, pp. 1205-1210.

O' Neill, Paul M, Stocks, Paul A, Sabbani, Sunil, Roberts, Natalie L, Amewu, Richard K, Shore, Emma R, Aljayyoussi, Ghaith, Angulo-Barturén, Iñigo, Belén, María, Díaz, Jiménez, Bazaga, Santiago Ferrer, Martínez, María Santos, Campo, Brice, Sharma, Raman, Charman, Susan A, Ryan, Eileen, Chen, Gong, Shackleford, David M, Davies, Jill, Nixon, Gemma L, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2018) 'Synthesis and profiling of benzylmorpholine 1,2,4,5-tetraoxane analogue N205: Towards tetraoxane scaffolds with potential for single dose cure of malaria.'. Bioorganic and Medicinal Chemistry, Vol 26, Issue 11, pp. 2996-3005.

Glaharn, Supattra, Punsawad, Chuchard, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Viriyavejakul, Parnpen (2018) 'Exploring pancreatic pathology in Plasmodium falciparum malaria patients.'. Scientific Reports, Vol 8, Issue 1, p. 10456.

Smit, Menno ORCID: https://orcid.org/0000-0003-3405-6638, Ochomo, Eric O, Aljayyoussi, Ghaith, Kwambai, Titus, Abong'o, Bernard, Chen, Tao ORCID: https://orcid.org/0000-0002-5489-6450, Bousema, Teun, Slater, Hannah C, Waterhouse, David, Bayoh, Nabie M, Gimnig, John E, Samuels, Aaron M, Desai, Meghna R, Phillips-Howard, Penelope ORCID: https://orcid.org/0000-0003-1018-116X, Kariuki, Simon K, Wang, Duolao ORCID: https://orcid.org/0000-0003-2788-2464, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and terKuile, Feiko ORCID: https://orcid.org/0000-0003-3663-5617 (2018) 'Safety and mosquitocidal efficacy of high-dose ivermectin when co-administered with dihydroartemisinin-piperaquine in Kenyan adults with uncomplicated malaria (IVERMAL): a randomised, double-blind, placebo-controlled trial'. Lancet Infectious Diseases, Vol 18, Issue 6, pp. 615-626.

de Kock, Miné, Tarning, Joel, Workman, Lesley, Allen, Elizabeth N, Tekete, Mamadou M, Djimde, Abdoulaye A, Bell, David J, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Barnes, Karen I and Denti, Paolo (2018) 'Population Pharmacokinetic properties of Sulfadoxine and Pyrimethamine: A pooled analysis to Inform Optimal Dosing in African Children with Uncomplicated Malaria.'. Antimicrobial Agents and Chemotherapy, Vol 62, Issue 5, e01370-17.

Aljayyoussi, Ghaith, Tyrer, Hayley, Ford, Louise, Sjoberg, Hanna, Pionnier, Nicolas ORCID: https://orcid.org/0000-0002-2379-4945, Waterhouse, David, Davies, Jill, Gamble, Joanne, Metuge, Haelly, Cook, Darren, Steven, Andrew, Sharma, Raman, Guimaraes, Ana, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cassidy, Andrew, Johnston, Kelly, Myhill, Laura, Hayward, Laura, Wanji, Samuel, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2018) 'Author Correction: Short-Course, High-Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis.'. Scientific Reports, Vol 8, Issue 1, p. 1384.

Török, M E, Aljayyoussi, Ghaith, Waterhouse, David, Chau, Tth, Mai, Nth, Phu, N H, Hien, T T, Hope, W, Farrar, J J and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2017) 'Suboptimal Exposure to Anti-TB Drugs in a TBM/HIV+ Population is not Related to Anti-retroviral Therapy.'. Clinical pharmacology and therapeutics, Vol 103, Issue 3, pp. 449-457.

Jiang, Zhengyun, Hong, Weiqian, Cui, Xiping, Gao, Hongcan, Wu, Panpan, Chen, Yingshan, Shen, Ding, Yang, Yang, Zhang, Bingjie, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, O'Neill, Paul M., Zhao, Suqing and Zhang, Kun (2017) 'Synthesis and structure–activity relationship of N4-benzylamine-N2-isopropyl-quinazoline-2,4-diamines derivatives as potential antibacterial agents'. RSC Advances, Vol 7, Issue 82, pp. 52227-52237.

Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Sharma, Raman, Aljayyoussi, Ghaith, Tyrer, Hayley, Gamble, Jo, Hayward, Laura, Priestley, Richard, Murphy, Emma ORCID: https://orcid.org/0000-0001-9421-7777, Davies, Jill, Waterhouse, David, Cook, Darren, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cassidy, Andrew, Steven, Andrew, Johnston, Kelly, Ford, Louise, Hemingway, Janet ORCID: https://orcid.org/0000-0002-3200-7173, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2017) 'Albendazole and antibiotics synergize to deliver short-course anti-Wolbachia curative treatments in preclinical models of filariasis'. Proceedings of the National Academy of Sciences of the United States of America, Vol 114, Issue 45, E9712-E9721.

Johnston, Kelly, Cook, Darren, Berry, Neil, Hong, Weiqian David, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Goddard, Megan, Ford, Louise, Nixon, Gemma, O'Neill, Paul, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2017) 'Identification and prioritization of novel anti-Wolbachia chemotypes from screening a 10,000-compound diversity library'. Science Advances, Vol 3, Issue 9, eaao1551.

Sloan, Derek, McCallum, Andrew, Schipani, Alessandro, Egan, Deirdre, Mwandumba, Henry ORCID: https://orcid.org/0000-0003-4470-3608, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Waterhouse, David, Banda, Gertrude, Allain, Theresa J, Owen, Andrew, Khoo, Saye H and Davies, Geraint R (2017) 'Genetic determinants of the pharmacokinetic variability of rifampicin in Malawian adults with pulmonary tuberculosis'. Antimicrobial Agents and Chemotherapy, Vol 61, Issue 7, e00210-e00217.

O'Neill, Paul M, Amewu, Richard K, Charman, Susan A, Sabbani, Sunil, Gnädig, Nina F, Straimer, Judith, Fidock, David A, Shore, Emma R, Roberts, Natalie L, Wong, Michael H-L, Hong, W David, Pidathala, Chandrakala, Riley, Chris, Murphy, Ben, Aljayyoussi, Ghaith, Gamo, Francisco Javier, Sanz, Laura, Rodrigues, Janneth, Cortes, Carolina Gonzalez, Herreros, Esperanza, Angulo-Barturén, Iñigo, Jiménez-Díaz, María Belén, Bazaga, Santiago Ferrer, Martínez-Martínez, María Santos, Campo, Brice, Sharma, Raman, Ryan, Eileen, Shackleford, David M, Campbell, Simon, Smith, Dennis A, Wirjanata, Grennady, Noviyanti, Rintis, Price, Ric N, Marfurt, Jutta, Palmer, Michael J, Copple, Ian M, Mercer, Amy E, Ruecker, Andrea, Delves, Michael J, Sinden, Robert E, Siegl, Peter, Davies, Jill, Rochford, Rosemary, Kocken, Clemens H M, Zeeman, Anne-Marie, Nixon, Gemma L, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2017) 'A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance.'. Nature Communications, Vol 8, e15159.

Hong, David, Gibbons, Peter, Leung, Suet C, Amewu, Richard, Stocks, Paul A, Stachulski, Andrew, Horta, Pedro, Cristiano, Maria L. S., Shone, Alison, Moss, Darren, Ardrey, Alison, Sharma, Raman, Warman, Ashley, Bedingfield, Paul, Fisher, Nicholas, Aljayyoussi, Ghaith, Mead, Sally, Caws, Maxine ORCID: https://orcid.org/0000-0002-9109-350X, Berry, Neil, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, O’Neill, Paul M and Nixon, Gemma L (2017) 'Rational Design, Synthesis, and Biological Evaluation of Heterocyclic Quinolones Targeting the Respiratory Chain of Mycobacterium tuberculosis'. Journal of Medicinal Chemistry, Vol 60, Issue 9, pp. 3703-3726.

Aljayyoussi, Ghaith, Jenkins, Victoria, Sharma, Raman, Donnellan, Samantha, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2017) 'Pharmacokinetic-Pharmacodynamic modelling of intracellular Mycobacterium tuberculosis growth and kill rates is predictive of clinical treatment duration'. Scientific Reports, Vol 7, Issue 502.

Aljayyoussi, Ghaith, Tyrer, Hayley, Ford, Louise, Sjoberg, Hanna, Pionnier, Nicolas ORCID: https://orcid.org/0000-0002-2379-4945, Waterhouse, David, Davies, Jill, Gamble, Jo, Metugene, Haelly, Cook, Darren, Steven, Andrew, Sharma, Raman, Guimaraes, Ana, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cassidy, Andrew, Johnston, Kelly, Myhill, Laura, Hayward, Laura, Wanji, Samuel, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2017) 'Short Course, High Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis'. Scientific Reports, Vol 7, Issue 210.

Mungthin, Mathirut, Watanatanasup, Ekularn, Sitthichot, Naruemon, Suwandittakul, Nantana, Khositnithikul, Rommanee and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2017) 'Influence of the pfmdr1 Gene on In Vitro Sensitivities of Piperaquine in Thai Isolates of Plasmodium falciparum.'. American Journal of Tropical Medicine and Hygiene, Vol 96, Issue 3, pp. 624-629.

Smit, Menno ORCID: https://orcid.org/0000-0003-3405-6638, Ochomo, Eric, Aljayyoussi, Ghaith, Kwambai, Titus, Abongo, Bernard, Bayoh, Nabie, Gimnig, John E, Samuels, Aaron, Desai, Meghna, Phillips-Howard, Penelope ORCID: https://orcid.org/0000-0003-1018-116X, Kariuki, Simon, Wang, Duolao ORCID: https://orcid.org/0000-0003-2788-2464, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and terKuile, Feiko ORCID: https://orcid.org/0000-0003-3663-5617 (2016) 'Efficacy and Safety of High-Dose Ivermectin for Reducing Malaria Transmission (IVERMAL): Protocol for a Double-Blind, Randomized, Placebo-Controlled, Dose-Finding Trial in Western Kenya'. Journal of Medical Internet Research, Vol 5, Issue 4, e213.

Bustinduy, Amaya L., Waterhouse, David, de Sousa-Figueiredo, Jose C, Roberts, Stephen A, Atuhaire, Aaron, Van Dam, Govert J, Corstjens, Paul L A M, Scott, Janet T, Stanton, Michelle ORCID: https://orcid.org/0000-0002-1754-4894, Kabatereine, Narcis B, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Hope, William W and Stothard, Russell ORCID: https://orcid.org/0000-0002-9370-3420 (2016) 'Population Pharmacokinetics and Pharmacodynamics of Praziquantel in Ugandan Children with Intestinal Schistosomiasis: Higher Dosages Are Required for Maximal Efficacy.'. mBio, Vol 7, Issue 4, e00227-16.

Aljayyoussi, Ghaith, Kay, Katherine, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2016) 'OptiMal-PK: an internet-based, user-friendly interface for the mathematical-based design of optimized anti-malarial treatment regimens.'. Malaria Journal, Vol 15, Issue 344.

Sahota, Amandip S, Gowda, Ravi, Arasaradnam, Ramesh P, Daulton, Emma, Savage, Richard S, Skinner, Jim R, Adams, Emily ORCID: https://orcid.org/0000-0002-0816-2835, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Covington, James A (2016) 'A simple breath test for tuberculosis using ion mobility: A pilot study.'. Tuberculosis (Edinburgh, Scotland), Vol 99, pp. 143-146.

Ismail, Hanafy ORCID: https://orcid.org/0000-0002-9953-9588, Barton, Victoria E., Panchana, Matthew, Charoensutthivarakul, Sitthivut, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and O'Neill, Paul M. (2016) 'A Click Chemistry-Based Proteomic Approach Reveals that 1,2,4-Trioxolane and Artemisinin Antimalarials Share a Common Protein Alkylation Profile'. Angewandte Chemie International Edition, Vol 128, Issue 22, pp. 6401-6405.

Sharma, Raman, Aljayyoussi, Ghaith, Tyrer, Hayley, Gamble, Jo, Hayward, Laura, Guimaraes, Ana, Davies, Jill, Waterhouse, David, Cook, Darren, Myhill, Laura, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cassidy, Andrew, Steven, Andrew, Johnston, Kelly, Ford, Louise, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2016) 'Minocycline as a re-purposed anti-Wolbachia macrofilaricide: superiority compared with doxycycline regimens in a murine infection model of human lymphatic filariasis'. Scientific Reports, Vol 6, p. 23458.

Schipani, Alessandro, Pertinez, Henry, Mlota, Rachel, Molyneux, Elizabeth, Lopez, Nuria, Dzinjalamala, Fraction K, van Oosterhout, Joep J, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Khoo, Saye and Davies, Gerry (2016) 'A simultaneous population pharmacokinetic analysis of rifampicin in Malawian adults and children.'. British journal of clinical pharmacology, Vol 81, Issue 4, pp. 679-87.

Ismail, Hanafy ORCID: https://orcid.org/0000-0002-9953-9588, Barton, Victoria, Phanchana, Matthew, Charoensutthivarakul, Sitthivut, Wong, Michael H L, Hemingway, Janet ORCID: https://orcid.org/0000-0002-3200-7173, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, O’Neill, Paul M and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2016) 'Artemisinin activity-based probes identify multiple molecular targets within the asexual stage of the malaria parasites Plasmodium falciparum 3D7'. Proceedings of the National Academy of Sciences, Vol 113, Issue 8, pp. 2080-2085.

Mandala, Wilson, Msefula, Chisomo, Gondwe, Esther, Gilchrist, James J, Graham, Stephen, Pensulo, Paul, Mwimaniwa, Grace, Banda, Meraby, Taylor, Terrie E, Molyneux, Elizabeth E, Drayson, Mark T, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Molyneux, Malcolm E and MacLennan, Calman A (2016) 'Lymphocyte Perturbations in Malawian Children with Severe and Uncomplicated Malaria.'. Clinical and vaccine immunology : CVI, Vol 23, Issue 2, pp. 95-103.

Croft, Simon L and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2015) 'The Nobel Prize in Medicine 2015: Two drugs that changed global health'. Science Translational Medicine, Vol 7, Issue 316.

Molyneux, David ORCID: https://orcid.org/0000-0001-8537-7947 and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2015) 'Reflections on the Nobel Prize for Medicine 2015 - The Public Health Legacy and Impact of Avermectin and Artemisinin.'. Trends in parasitology, Vol 31, Issue 12, pp. 605-607.

O'Neill, Paul M and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2015) 'A Quinoline Carboxamide Antimalarial Drug Candidate Uniquely Targets Plasmodia at Three Stages of the Parasite Life Cycle'. Angewandte Chemie (International ed. in English), Vol 54, Issue 46, pp. 13504-6.

Oosterhout, J J van, Dzinjalamala, F K, Dimba, A, Waterhouse, David, Davies, G, Zijlstra, E E, Molyneux, Malcolm E, Molyneux, E M and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2015) 'Pharmacokinetics of anti-tuberculosis drugs in HIV-positive and HIV-negative adults in Malawi'. Antimicrobial Agents and Chemotherapy, Vol 59, Issue 10, pp. 6175-6180.

McConville, Matthew, Fernández, Jorge, Angulo-Barturen, Íñigo, Bahamontes-Rosa, Noemi, Ballell-Pages, Lluis, Castañeda, Pablo, de Cózar, Cristina, Crespo, Benigno, Guijarro, Laura, Jiménez-Díaz, María Belén, Martínez-Martínez, Maria S, de Mercado, Jaime, Santos-Villarejo, Ángel, Sanz, Laura M, Frigerio, Micol, Washbourn, Gina, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Nixon, Gemma L, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Berry, Neil G, Blackman, Michael J, Calderón, Félix and O'Neill, Paul M (2015) 'Carbamoyl Triazoles, Known Serine Protease Inhibitors, Are a Potent New Class of Antimalarials.'. Journal of medicinal chemistry, Vol 58, Issue 16, pp. 6448-6455.

Charoensutthivarakul, Sitthivut, David Hong, W., Leung, Suet C., Gibbons, Peter D., Bedingfield, Paul, Nixon, Gemma L., Lawrenson, Alexandre S., Berry, Neil G., Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and O'Neill, Paul (2015) '2-Pyridylquinolone antimalarials with improved antimalarial activity and physicochemical properties'. MedChemComm, Vol 6, Issue 7, pp. 1252-1259.

Capper, Michael J., O’Neill, Paul M., Fisher, Nicholas, Strange, Richard W., Moss, Darren M., Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Berry, Neil G., Lawrenson, Alexandre S., Hasnain, S. Samar, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and Antonyuk, Svetlana V. (2015) 'Antimalarial 4(1H)-pyridones bind to the Qisite of cytochromebc1'. Proceedings of the National Academy of Sciences, Vol 112, Issue 3, pp. 755-760.

Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cook, Darren, Johnston, Kelly, Ford, Louise, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2014) 'Development and Validation of a High-Throughput Anti-Wolbachia Whole-Cell Screen: A Route to Macrofilaricidal Drugs against Onchocerciasis and Lymphatic Filariasis'. Journal of Biomolecular Screening, Vol 20, Issue 1, pp. 64-69.

Chaijaroenkul, Wanna, Mubaraki, Murad A., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Na-Bangchang, Kesara (2014) 'Metabolite footprinting of Plasmodium falciparum following exposure to Garcinia mangostana Linn. crude extract'. Experimental Parasitology, Vol 145, pp. 80-86.

Requena-Mendez, A., Davies, Geraint, Waterhouse, David, Ardrey, Alison, Jave, O., Lopez-Romero, S. L., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Moore, D. A. J. (2014) 'Effects of Dosage, Comorbidities, and Food on Isoniazid Pharmacokinetics in Peruvian Tuberculosis Patients'. Antimicrobial Agents and Chemotherapy, Vol 58, Issue 12, pp. 7164-7170.

Valea, I., Tinto, H., Traore/Coulibaly, M., Toe, L. C., Lindegardh, N., Tarning, J., Van Geertruyden, J.-P., D'Alessandro, U., Davies, G. R. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2014) 'Pharmacokinetics of co-formulated mefloquine and artesunate in pregnant and non-pregnant women with uncomplicated Plasmodium falciparum infection in Burkina Faso'. Journal of Antimicrobial Chemotherapy, Vol 69, Issue 9, pp. 2499-2507.

Stothard, Russell ORCID: https://orcid.org/0000-0002-9370-3420, Stanton, Michelle ORCID: https://orcid.org/0000-0002-1754-4894, Bustinduy, Amaya L., Sousa-Figueiredo, José C., Van Dam, Govert J., Betson, Martha, Waterhouse, David, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Allan, Fiona, Hassan, Amir, Al-Helal, Mohammed A., Memish, Ziad A. and Rollinson, David (2014) 'Diagnostics for schistosomiasis in Africa and Arabia: a review of present options in control and future needs for elimination'. Parasitology, Vol 141, Issue 14, pp. 1947-1961.

Hall, Adam J., Chappell, Michael J., Aston, John A.D. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2014) 'Reprint of “Pharmacokinetic modelling of the anti-malarial drug artesunate and its active metabolite dihydroartemisinin”'. Computer Methods and Programs in Biomedicine, Vol 114, Issue 3, e14-e28.

Antoine, Thomas, Fisher, Nicholas, Amewu, R., O'Neill, P. M., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2014) 'Rapid kill of malaria parasites by artemisinin and semi-synthetic endoperoxides involves ROS-dependent depolarization of the membrane potential'. Journal of Antimicrobial Chemotherapy, Vol 69, Issue 4, pp. 1005-1016.

Salcedo, Enrique, Caamno-Gutierrez, Eva, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2014) 'The proliferating cell hypothesis: a metabolic framework for Plasmodium growth and development'. Trends in Parasitology, Vol 30, Issue 4, pp. 170-175.

Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, Hoerauf, Achim, Townson, Simon, Slatko, Barton E. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2014) 'Anti-Wolbachia drug discovery and development: safe macrofilaricides for onchocerciasis and lymphatic filariasis'. Parasitology, Vol 141, Issue 01, pp. 119-127.

Stocks, P.A., Barton, V., Antoine, T., Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and O'Neill, P. M. (2014) 'Novel inhibitors of the Plasmodium falciparum electron transport chain'. Parasitology, Vol 141, Issue 1, pp. 50-65.

Amewu, Richard K., Chadwick, James, Hussain, Afthab, Panda, Somnath, Rinki, Rinki, Janneh, Omar, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Miguel, Candel, Burrell-Saward, Hollie, Vivas, Livia and O’Neill, Paul M. (2013) 'Synthesis and evaluation of the antimalarial, anticancer, and caspase 3 activities of tetraoxane dimers'. Bioorganic and Medicinal Chemistry, Vol 21, Issue 23, pp. 7392-7397.

Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Boulton, Ian C (2013) 'CRIMALDDI: a prioritized research agenda to expedite the discovery of new anti-malarial drugs'. Malaria Journal, Vol 12, : 395.

Vial, Henri, Taramelli, Donatella, Boulton, Ian C, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Doerig, Christian and Chibale, Kelly (2013) 'CRIMALDDI: platform technologies and novel anti-malarial drug targets.'. Malaria Journal, Vol 12, e396.

Gitau, Evelyn, Kokwaro, Gilbert O, Karanja, Henry, Newton, Charles R J C and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2013) 'Plasma and cerebrospinal proteomes from children with cerebral malaria differ from those of children with other encephalopathies.'. Journal of Infectious Disease, Vol 208, Issue 9, pp. 1494-1503.

Hall, Adam J, Chappell, Michael J, Aston, John A D and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2013) 'Pharmacokinetic modelling of the anti-malarial drug artesunate and its active metabolite dihydroartemisinin.'. Computer Methods and Programs in Biomedicine, Vol 112, Issue 1, pp. 1-15.

Nixon, Gemma, Pidathala, Chandrakala, Shone, Alison E, Antoine, Thomas, Fisher, Nicholas, O'Neill, Paul M, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2013) 'Targeting the mitochondrial electron transport chain of Plasmodium falciparum: new strategies towards the development of improved antimalarials for the elimination era.'. Future medicinal chemistry, Vol 5, Issue 13, pp. 1573-1591.

Oliveira, Rudi, Newton, Ana S, Guedes, Rita C, Miranda, Daniela, Amewu, Richard K, Srivastava, Abhishek, Gut, Jiri, Rosenthal, Philip J, O'Neill, Paul M, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Lopes, Francisca and Moreira, Rui (2013) 'An endoperoxide-based hybrid approach to deliver falcipain inhibitors inside malaria parasites.'. ChemMedChem, Vol 8, Issue 9, pp. 1528-1536.

Patzewitz, Eva-Maria, Salcedo, Enrique, Wong, Eleanor H, Sethia, Sonal, Stocks, Paul A., Maughan, Spencer C, Murray, James A H, Krishna, Sanjeev, Bray, Patrick, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Müller, Sylke (2013) 'Glutathione transport: a new role for PfCRT in chloroquine resistance.'. Antioxidants and Redox Signaling, Vol 19, Issue 7, pp. 683-95.

Nixon, Gemma, Moss, Darren M., Shone, Alison, Lalloo, David ORCID: https://orcid.org/0000-0001-7680-2200, Fisher, Nicholas, O'Neill, Paul M, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2013) 'Antimalarial pharmacology and therapeutics of atovaquone.'. The Journal of Antimicrobial Chemotherapy, Vol 68, Issue 5, pp. 977-985.

La Pensée, Louise, Sabbani, Sunil, Sharma, Raman, Bhamra, Inder, Shore, Emma, Chadwick, Amy E, Berry, Neil G, Firman, James, Araujo, Nuna C, Cabral, Lília, Cristiano, Maria L S, Bateman, Cerys, Janneh, Omar, Gavrila, Adelina, Wu, Yi Hang, Hussain, Afthab, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Stocks, Paul A., Cosstick, Rick and O'Neill, Paul M (2013) 'Artemisinin-polypyrrole conjugates: synthesis, DNA binding studies and preliminary antiproliferative evaluation.'. ChemMedChem, Vol 8, Issue 5, pp. 709-718.

Okombo, J., Kiara, S. M., Abdirahman, A., Mwai, L., Ohuma, E., Borrmann, S., Nzila, A. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2013) 'Antimalarial activity of isoquine against Kenyan Plasmodium falciparum clinical isolates and association with polymorphisms in pfcrt and pfmdr1 genes'. Journal of Antimicrobial Chemotherapy, Vol 68, Issue 4, pp. 786-788.

Warman, Ashley, Rito, Teresa S, Fisher, Nicholas, Moss, Darren M., Berry, Neil G, O'Neill, Paul M, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2013) 'Antitubercular pharmacodynamics of phenothiazines'. Journal of Antimicrobial Chemotherapy, Vol 68, Issue 4, pp. 869-880.

Salcedo, Enrique and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2013) 'The folate metabolic network of Falciparum malaria.'. Molecular and Biochemical Parasitology, Vol 188, Issue 1, pp. 51-62.

Srivastava, Abhishek, Waterhouse, David, Ardrey, Alison and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2012) 'Quantification of rifampicin in human plasma and cerebrospinal fluid by a highly sensitive and rapid liquid chromatographic-tandem mass spectrometric method.'. Journal of pharmaceutical and biomedical analysis, Vol 70, pp. 523-8.

Salcedo, Enrique, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2012) 'A yeast expression system for functional and pharmacological studies of the malaria parasite Ca2+/H+ antiporter.'. Malaria Journal, Vol 11, p. 254.

Copple, Ian M, Mercer, Amy E, Firman, James, Donegan, Gail, Herpers, Bram, Wong, Michael Hl, Chadwick, James, Bringela, Andreia D, Cristiano, Maria L S, van de Water, Bob, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, O'Neill, Paul M and Park, B Kevin (2012) 'Examination of the cytotoxic and embryotoxic potential and underlying mechanisms of next-generation synthetic trioxolane and tetraoxane antimalarials.'. Molecular medicine (Cambridge, Mass.), Vol 18, pp. 1045-55.

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Fisher, Nicholas, Shone, Alison, Mubaraki, Murad A., Srivastava, Abhishek, Hill, Alasdair, Antoine, Thomas, Warman, Ashley, Davies, Jill, Pidathala, Chandrakala, Amewu, Richard K, Leung, Suet C, Sharma, Raman, Gibbons, Peter, Hong, David W, Pacorel, Bénédicte, Lawrenson, Alexandre S, Charoensutthivarakul, Sitthivut, Taylor, Lee, Berger, Olivier, Mbekeani, Alison, Stocks, Paul A., Nixon, Gemma, Chadwick, James, Hemingway, Janet ORCID: https://orcid.org/0000-0002-3200-7173, Delves, Michael J, Sinden, Robert E, Zeeman, Anne-Marie, Kocken, Clemens H M, Berry, Neil G, O'Neill, Paul M and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2012) 'Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria.'. Proceedings of the National Academy of Sciences of the United States of America, Vol 109, Issue 21, pp. 8298-303.

Srivastava, A. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2012) 'Development and validation of a highly sensitive LC-MS/MS assay for determination of rifampicin in human plasma: application to clinical pharmacokinetic study'. British Journal of Clinical Pharmacology, Vol 73, Issue 6, pp. 998-999.

Vallières, Cindy, Fisher, Nicholas, Antoine, Thomas, Al-Helal, Mohammed, Stocks, Paul A., Berry, Neil G, Lawrenson, Alexandre S, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, O'Neill, Paul M, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and Meunier, Brigitte (2012) 'HDQ, a potent inhibitor of Plasmodium falciparum proliferation, binds to the quinone reduction site of the cytochrome bc1 complex.'. Antimicrobial Agents and Chemotherapy, Vol 56, Issue 7, pp. 3739-47.

Sharma, Raman, Lawrenson, Alexandre S, Fisher, Nicholas, Warman, Ashley, Shone, Alison, Hill, Alasdair, Mbekeani, Alison, Pidathala, Chandrakala, Amewu, Richard K, Leung, Suet, Gibbons, Peter, Hong, David W, Stocks, Paul A., Nixon, Gemma L, Chadwick, James, Shearer, Joanne, Gowers, Ian, Cronk, David, Parel, Serge P, O'Neill, Paul M, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and Berry, Neil G (2012) 'Identification of novel antimalarial chemotypes via chemoinformatic compound selection methods for a high-throughput screening program against the novel malarial target, PfNDH2: increasing hit rate via virtual screening methods.'. Journal of medicinal chemistry, Vol 55, Issue 7, pp. 3144-54.

Fisher, Nicholas, Abd Majid, Roslaini, Antoine, Thomas, Al-Helal, Mohammed, Warman, Ashley, Johnson, David, Lawrenson, Alexandre S., Ranson, Hilary ORCID: https://orcid.org/0000-0003-2332-8247, O'Neill, Paul M, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2012) 'Cytochrome b mutation Y268S conferring atovaquone resistance phenotype in malaria parasite results in reduced parasite bc1 catalytic turnover and protein expression.'. The Journal of Biological Chemistry, Vol 287, Issue 13, pp. 9731-9741.

Goonetilleke, U. R., Scarborough, M., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Hussain, S., Kadioglu, A. and Gordon, Stephen ORCID: https://orcid.org/0000-0001-6576-1116 (2012) 'Death is associated with complement C3 depletion in cerebrospinal fluid of patients with pneumococcal meningitis.'. mBio, Vol 3, Issue 2, e00272-11.

Pidathala, Chandrakala, Amewu, Richard, Pacorel, Bénédicte, Nixon, Gemma L, Gibbons, Peter, Hong, W David, Leung, Suet C, Berry, Neil G, Sharma, Raman, Stocks, Paul A., Srivastava, Abhishek, Shone, Alison, Charoensutthivarakul, Sitthivut, Taylor, Lee, Berger, Olivier, Mbekeani, Alison, Hill, Alasdair, Fisher, Nicholas, Warman, Ashley, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and O'Neill, Paul M (2012) 'Identification, design and biological evaluation of bisaryl quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2).'. Journal of medicinal chemistry, Vol 55, Issue 5, pp. 1831-1843.

Leung, Suet C, Gibbons, Peter, Amewu, Richard, Nixon, Gemma L, Pidathala, Chandrakala, Hong, W David, Pacorel, Bénédicte, Berry, Neil G, Sharma, Raman, Stocks, Paul A., Srivastava, Abhishek, Shone, Alison, Charoensutthivarakul, Sitthivut, Taylor, Lee, Berger, Olivier, Mbekeani, Alison, Hill, Alasdair, Fisher, Nicholas, Warman, Ashley, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and O'Neill, Paul M (2012) 'Identification, design and biological evaluation of heterocyclic quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2).'. Journal of medicinal chemistry, Vol 55, Issue 5, pp. 1844-1857.

Cowley, Robin, Leung, Suet, Fisher, Nicholas, Al-Helal, Mohammed, Berry, Neil G., Lawrenson, Alexandre S., Sharma, Raman, Shone, Alison, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and O′Neill, Paul M. (2012) 'The development of quinolone esters as novel antimalarial agents targeting the Plasmodium falciparum bc1 protein complex'. MedChemComm, Vol 3, Issue 1, pp. 39-44.

Requena-Mendez, A., Davies, G., Ardrey, Alison, Jave, O., Lopez-Romero, S. L., Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Moore, D. A. J. (2012) 'Pharmacokinetics of Rifampin in Peruvian Tuberculosis Patients with and without Comorbid Diabetes or HIV'. Antimicrobial Agents and Chemotherapy, Vol 56, Issue 5, pp. 2357-2363.

Salcedo, Enrique, Ochong, Edwin, Beveridge, Susan, Johnson, David, Nzila, Alexis, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Stocks, Paul A., O'Neill, Paul M, Krishna, Sanjeev, Bray, Patrick and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2011) 'The molecular basis of folate salvage in Plasmodium falciparum: Characterization of two folate transporters.'. The Journal of Biological Chemistry, Vol 286, Issue 52, pp. 44659-44668.

Berger, Olivier, Kaniti, Archana, Ba, Christophe Tran van, Vial, Henri, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Bray, Patrick and O'Neill, Paul M (2011) 'Synthesis and Antimalarial Activities of a Diverse Set of Ariazole-Containing Furamidine Analogues.'. ChemMedChem, Vol 6, Issue 11, pp. 2094-2108.

Bousejra-El Garah, Fatima, Wong, Michael He-Long, Amewu, Richard K, Muangnoicharoen, Sant, Maggs, James L, Stigliani, Jean-Luc, Park, B Kevin, Chadwick, James, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and O'Neill, Paul M (2011) 'Comparison of the reactivity of antimalarial 1,2,4,5-tetraoxanes with 1,2,4-trioxolanes in the presence of ferrous iron salts, heme, and ferrous iron salts/phosphatidylcholine.'. Journal of medicinal chemistry, Vol 54, Issue 19, pp. 6443-55.

Chadwick, James, Amewu, Richard K, Marti, Francesc, Garah, Fatima Bousejra-El, Sharma, Raman, Berry, Neil G, Stocks, Paul A., Burrell-Saward, Hollie, Wittlin, Sergio, Rottmann, Matthias, Brun, Reto, Taramelli, Donatella, Parapini, Silvia, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and O'Neill, Paul M (2011) 'Antimalarial mannoxanes: hybrid antimalarial drugs with outstanding oral activity profiles and a potential dual mechanism of action.'. ChemMedChem, Vol 6, Issue 8, pp. 1357-61.

Gordey, Erin E, Yadav, Paras N, Merrin, Marcus P, Davies, Jill, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Woodman, Grant M J, Sadowy, Amber L, Smith, Todd G and Gossage, Robert A (2011) 'Synthesis and biological activities of 4-N-(anilinyl-n-[oxazolyl])-7-chloroquinolines (n=3' or 4') against Plasmodium falciparum in in vitro models.'. Bioorganic & Medicinal Chemistry Letters, Vol 21, Issue 15, pp. 4512-5.

Gitau, Evelyn, Kokwaro, Gilbert O, Newton, Charles Rjc and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2011) 'Global proteomic analysis of plasma from mice infected with Plasmodium berghei ANKA using two dimensional gel electrophoresis and matrix assisted laser desorption ionization-time of flight mass spectrometry.'. Malaria Journal, Vol 10, p. 205.

Chaijaroenkul, Wanna, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Mungthin, Mathirut, Johnson, David, Owen, Andrew, Bray, Patrick and Na-Bangchang, Kesara (2011) 'Sequence and gene expression of chloroquine resistance transporter (pfcrt) in the association of in vitro drugs resistance of Plasmodium falciparum.'. Malaria Journal, Vol 10, Issue 1, p. 42.

Bell, David J., Nyirongo, S.K., Mukaka, Mavuto, Molyneux, M.E., Winstanley, P.A. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2011) 'Population pharmacokinetics of sulfadoxine and pyrimethamine in Malawian children with malaria.'. Clinical pharmacology and therapeutics, Vol 89, Issue 2, pp. 268-275.

Gibbons, Peter, Verissimo, Edite, Araujo, Nuna C, Barton, Victoria, Nixon, Gemma L, Amewu, Richard K, Chadwick, James, Stocks, Paul A., Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Srivastava, Abhishek, Rosenthal, Philip J, Gut, Jiri, Guedes, Rita C, Moreira, Rui, Sharma, Raman, Berry, Neil, Cristiano, M Lurdes S, Shone, Alison, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and O'Neill, Paul M (2010) 'Endoperoxide carbonyl falcipain 2/3 inhibitor hybrids: toward combination chemotherapy of malaria through a single chemical entity.'. Journal of medicinal chemistry, Vol 53, Issue 22, pp. 8202-6.

Finaurini, Sara, Ronzoni, Luisa, Colancecco, Alessandra, Cattaneo, Alessandra, Cappellini, Maria Domenica, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Taramelli, Donatella (2010) 'Selective toxicity of dihydroartemisinin on human CD34+ erythroid cell differentiation.'. Toxicology, Vol 276, Issue 2, pp. 128-34.

Lucumi, Edinson, Darling, Claire, Jo, Hyunil, Napper, Andrew D., Chandramohanadas, Rajesh, Fisher, Nicholas, Shone, Alison, Jing, Huiyan, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, DeGrado, William F, Diamond, Scott L and Greenbaum, Doron C (2010) 'Discovery of potent small-molecule inhibitors of multidrug-resistant Plasmodium falciparum using a novel miniaturized high-throughput luciferase-based assay.'. Antimicrobial Agents and Chemotherapy, Vol 54, Issue 9, pp. 3597-3604.

Goonetilleke, Upali R, Scarborough, Matthew, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Gordon, Stephen ORCID: https://orcid.org/0000-0001-6576-1116 (2010) 'Proteomic analysis of cerebrospinal fluid in pneumococcal meningitis reveals potential biomarkers associated with survival.'. Journal of Infectious Disease, Vol 202, Issue 4, pp. 542-50.

Mungthin, Mathirut, Khositnithikul, Rommanee, Sitthichot, Naruemon, Suwandittakul, Nantana, Wattanaveeradej, Veerachai, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Na-Bangchang, Kesara (2010) 'Association between the pfmdr1 gene and in vitro artemether and lumefantrine sensitivity in Thai isolates of Plasmodium falciparum.'. American Journal of Tropical Medicine and Hygiene, Vol 83, Issue 5, pp. 1005-1009.

Barton, Victoria, Fisher, Nicholas, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and O'Neill, Paul M. (2010) 'Inhibiting Plasmodium cytochrome bc1: a complex issue.'. Current Opinion in Chemical Biology, Vol 14, Issue 4, pp. 440-446.

Boulton, Ian C, Nwaka, Solomon, Bathurst, Ian, Lanzer, Michael, Taramelli, Donatella, Vial, Henri, Doerig, Christian, Chibale, Kelly and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2010) 'CRIMALDDI: a co-ordinated, rational, and integrated effort to set logical priorities in anti-malarial drug discovery initiatives.'. Malaria Journal, Vol 9, Issue :202.

O'Neill, Paul M, Amewu, Richard K, Nixon, Gemma L, Bousejra ElGarah, Fatima, Mungthin, Mathirut, Chadwick, James, Shone, Alison, Vivas, Livia, Lander, Hollie, Barton, Victoria, Muangnoicharoen, Sant, Bray, Patrick, Davies, Jill, Park, B Kevin, Wittlin, Sergio, Brun, Reto, Preschel, Michael, Zhang, Kesheng and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2010) 'Identification of a 1,2,4,5-tetraoxane antimalarial drug-development candidate (RKA 182) with superior properties to the semisynthetic artemisinins.'. Angewandte Chemie (International ed. in English), Vol 49, Issue 33, pp. 5693-7.

Barton, Victoria, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Chadwick, James, Hill, Alasdair and O'Neill, Paul M (2010) 'Rationale design of biotinylated antimalarial endoperoxide carbon centered radical prodrugs for applications in proteomics.'. Journal of medicinal chemistry, Vol 53, Issue 11, pp. 4555-4559.

Amewu, Richard, Gibbons, Peter, Mukhtar, Amira, Stachulski, Andrew V., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Hall, Charlotte, Rimmer, Karen, Davies, Jill, Vivas, Livia, Bacsa, John, Mercer, Amy E., Nixon, Gemma, Stocks, Paul A. and O'Neill, Paul M. (2010) 'Synthesis, in vitro and in vivo antimalarial assessment of sulfide, sulfone and vinyl amide-substituted 1,2,4-trioxanes prepared via thiol-olefin co-oxygenation (TOCO) of allylic alcohols.'. Organic & biomolecular chemistry, Vol 8, Issue 9, pp. 2068-77.

de Souza, J Brian, Okomo, Uduak, Alexander, Neal D, Aziz, Naveed, Owens, Benjamin M J, Kaur, Harparkash, Jasseh, Momodou, Muangnoicharoen, Sant, Sumariwalla, Percy F, Warhurst, David C, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Conway, David J, Ulloa, Luis, Tracey, Kevin J, Foxwell, Brian M J, Kaye, Paul M and Walther, Michael (2010) 'Oral activated charcoal prevents experimental cerebral malaria in mice and in a randomized controlled clinical trial in man did not interfere with the pharmacokinetics of parenteral artesunate.'. PLoS ONE, Vol 5, Issue 4, e9867.

Chadwick, James, Jones, Michael, Mercer, Amy E, Stocks, Paul A., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Park, B Kevin and O'Neill, Paul M (2010) 'Design, synthesis and antimalarial/anticancer evaluation of spermidine linked artemisinin conjugates designed to exploit polyamine transporters in Plasmodium falciparum and HL-60 cancer cell lines.'. Bioorganic and Medicinal Chemistry, Vol 18, Issue 7, pp. 2586-97.

Miller, A. K., Bandyopadhyay, N., Wootton, D. G., Duparc, S., Kirby, P. L., Winstanley, P. A. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2009) 'Pharmacokinetics of chlorproguanil, dapsone, artesunate and their major metabolites in patients during treatment of acute uncomplicated Plasmodium falciparum malaria'. European Journal of Clinical Pharmacology, Vol 65, Issue 10, pp. 977-987.

Bell, David J., Wootton, D., Mukaka, Mavuto, Montgomery, Jacqui, Kayange, N., Chimpeni, P., Hughes, D. A., Molyneux, Malcolm E, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Winstanley, P. A. and Lalloo, David ORCID: https://orcid.org/0000-0001-7680-2200 (2009) 'Measurement of adherence, drug concentrations and the effectiveness of artemether-lumefantrine, chlorproguanil-dapsone or sulphadoxine-pyrimethamine in the treatment of uncomplicated malaria in Malawi'. Malaria Journal, Vol 8, p. 11.

Premji, Z., Umeh, R. E., Owusu-Agyei, S., Esamai, F., Ezedinachi, E. U., Oguche, S., Borrmann, S., Sowunmi, A., Duparc, S., Kirby, P. L., Pamba, A., Kellam, L., Guiguemdé, R., Greenwood, B., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Winstanley, P. A. (2009) 'Chlorproguanil - Dapsone - Artesunate versus artemether - Lumefantrine: A randomized, double-blind phase III trial in African children and adolescents with uncomplicated Plasmodium falciparum malaria'. PLoS ONE, Vol 4, Issue 8, e6682.

Nkhoma, Standwell, Nair, S., Mukaka, Mavuto, Molyneux, Malcolm E, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Anderson, T. J. C. (2009) 'Parasites bearing a single copy of the multi-drug resistance gene (pfmdr-1) with wild-type SNPs predominate amongst Plasmodium falciparum isolates from Malawi'. Acta Tropica, Vol 111, Issue 1, pp. 78-81.

Mwai, L., Ochong, Edwin, Abdirahman, A., Kiara, S. M., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Kokwaro, G., Sasi, P., Marsh, Kevin, Borrmann, S., Mackinnon, M. and Nzila, Alexis (2009) 'Chloroquine resistance before and after its withdrawal in Kenya'. Malaria Journal, Vol 8, p. 106.

O'Neill, Paul M., Shone, Alison, Stanford, Deborah, Nixon, Gemma, Asadollahy, Eghbaleh, Park, B. Kevin, Maggs, James L., Roberts, Phil, Stocks, Paul A., Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Bray, Patrick, Davies, Jill, Berry, Neil, Hall, Charlotte, Rimmer, Karen, Winstanley, Peter A., Hindley, Stephen, Bambal, Ramesh B., Davis, Charles B., Bates, Martin, Gresham, Stephanie L., Brigandi, Richard A., Gomez-de-las-Heras, Federico M., Gargallo, Domingo V., Parapini, Silvia, Vivas, Livia, Lander, Hollie, Taramelli, Donatella and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2009) 'Synthesis, Antimalarial Activity, and Preclinical Pharmacology of a Novel Series of 4′-Fluoro and 4′-Chloro Analogues of Amodiaquine. Identification of a Suitable “Back-Up” Compound for N-tert-Butyl Isoquine'. Journal of Medicinal Chemistry, Vol 52, Issue 7, pp. 1828-1844.

Jones, M., Mercer, A. E., Stocks, Paul A., La Pensee, L. J. I., Cosstick, R., Park, B. K., Kennedy, M. E., Piantanida, I., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Davies, Jill, Bray, Patrick, Rawe, S. L., Baird, J., Charidza, T., Janneh, O. and O'Neill, P. M. (2009) 'Antitumour and antimalarial activity of artemisinin-acridine hybrids'. Bioorganic & Medicinal Chemistry Letters, Vol 19, Issue 7, pp. 2033-2037.

Alker, Alisa P., Juliano, Jonathan J., Meshnick, Steven R., Owen, Andrew, Ochong, Edwin, Bell, David J., Johnson, David, d'Alessandro, Umberto, Mulenga, Modest, Muangnoicharoen, Sant, Van Geertruyden, J. P., Winstanley, Peter A., Bray, Patrick and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2009) 'Plasmodium falciparum and Dihydrofolate Reductase I164L Mutations in Africa Reply'. Antimicrobial Agents and Chemotherapy, Vol 53, Issue 4, pp. 1722-1723.

Muangnoicharoen, Sant, Johnson, David, Looareesuwan, S., Krudsood, S. and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2009) 'Role of Known Molecular Markers of Resistance in the Antimalarial Potency of Piperaquine and Dihydroartemisinin In Vitro'. Antimicrobial Agents and Chemotherapy, Vol 53, Issue 4, pp. 1362-1366.

Araujo, N. C. P., Barton, V., Jones, M., Stocks, Paul A., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Davies, Jill, Bray, Patrick, Shone, Alison, Cristiano, M. L. S. and O'Neill, P. M. (2009) 'Semi-synthetic and synthetic 1,2,4-trioxaquines and 1,2,4-trioxolaquines: synthesis, preliminary SAR and comparison with acridine endoperoxide conjugates'. Bioorganic & Medicinal Chemistry Letters, Vol 19, Issue 7, pp. 2038-2043.

Goonetilleke, U, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Gordon, Stephen ORCID: https://orcid.org/0000-0001-6576-1116 (2009) 'Could Proteomic Research Deliver the Next Generation of Treatments for Pneumococcal Meningitis?'. Interdisciplinary Perspectives on Infectious Diseases, Vol 2009, Article ID 214216.

Lian, L. Y., Al-Helal, Mohammed, Roslaini, A. M., Fisher, Nicholas, Bray, Patrick, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2009) 'Glycerol: An unexpected major metabolite of energy metabolism by the human malaria parasite'. Malaria Journal, Vol 8, p. 38.

O'Neill, Paul M., Park, B. Kevin, Shone, Alison, Maggs, James L., Roberts, Phillip, Stocks, Paul A., Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Bray, Patrick, Gibbons, Peter, Berry, Neil, Winstanley, Peter A., Mukhtar, Amira, Bonar-Law, Richard, Hindley, Stephen, Bambal, Ramesh B., Davis, Charles B., Bates, Martin, Hart, Timothy K., Gresham, Stephanie L., Lawrence, Ron M., Brigandi, Richard A., Gomez-delas-Heras, Federico M., Gargallo, Domingo V. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2009) 'Candidate Selection and Preclinical Evaluation of N-tert-Butyl Isoquine (GSK369796), An Affordable and Effective 4-Aminoquinoline Antimalarial for the 21st Century'. Journal of Medicinal Chemistry, Vol 52, Issue 5, pp. 1408-1415.

Davis, C. B., Bambal, R., Moorthy, G. S., Hugger, E., Xiang, H., Park, R. K., Shone, Alison, O'Neill, P. M. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2009) 'Comparative Preclinical Drug Metabolism and Pharmacokinetic Evaluation of Novel 4-Aminoquinoline Anti-Malarials'. Journal of Pharmaceutical Sciences, Vol 98, Issue 1, pp. 362-377.

Premji, Z., Umeh, R. E., Owusu-Agyei, S., Esamai, F., Ezedinachi, E., Oguche, S., Borrmann, S., Sowunmi, A., Duparc, S., Kirby, P. L., Pamba, A., Kellam, L., Guiguemde, R., Greenwood, B., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Winstanley, P. A. (2008) 'Chlorproguanil-Dapsone-Artesu Nate Vs. Artemether-Lumefantrine: A Randomised, Double-Blind Phase Iii Trial for the Treatment of Acute, Uncomplicated Plasmodium Falciparum Malaria in African Children and Adolescents'. American Journal of Tropical Medicine and Hygiene, Vol 79, Issue 6 Supp, p. 225.

Tiono, A., Dicko, A., Nclububa, D. A., Abenyega, T., Pitmang, S., Awobusuyi, J., Pamba, A., Duparc, S., Goh, L. E., Harrell, E., Carter, N., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Greenwood, B. and Winstanley, P. A. (2008) 'Chlorproguanil-Dapsone-Artesunate Vs. Chlorproguanil-Dapsone: A Randomised, Double-Blind Phase Iii Trial for the Treatment of Acute Uncomplicated Plasmodium Falciparum Malaria'. American Journal of Tropical Medicine and Hygiene, Vol 79, Issue 6 Supp, p. 172.

Mandala, W. L., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Molyneux, Malcolm E and MacLennan, C. A. (2008) 'Leucocytes and Cytokine Production in Pathogenesis of Severe Malaria in Malawian Children'. American Journal of Tropical Medicine and Hygiene, Vol 79, Issue 6 Supp, p. 100.

Johnson, David and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2008) 'Mechanisms of Drug Induced Gene Expression in Plasmodium Falciparum'. American Journal of Tropical Medicine and Hygiene, Vol 79, Issue 6 Supp, p. 301.

Fidock, D. A., Eastman, R. T., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Meshnick, S. R. (2008) 'Recent highlights in antimalarial drug resistance and chemotherapy research'. Trends in Parasitology, Vol 24, Issue 12, pp. 537-544.

Straimer, J., Sasi, P., Abdulrahaman, A., Rippert, A., Mwai, L., Schieck, E., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Borrmann, S. (2008) 'Relationship between Persistence of Subpatent Asexual Plasmodium Falciparum Infections and Subsequent Recrudescence after Antimalarial Treatment'. American Journal of Tropical Medicine and Hygiene, Vol 79, Issue 6 Supp, p. 291.

Dzinjalamala, F. K., Laufer, M. K., Thesing, P., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Reed, J. L., Hughes, D. M., Forrest, G., Taylor, T. E. and Plowe, C. V. (2008) 'Reversed-Phase High-Performance Liquid Chromatographic Assays for Determining Chloroquine in Whole Blood Specimens'. American Journal of Tropical Medicine and Hygiene, Vol 79, Issue 6 Supp, p. 290.

Ochong, Edwin, Salcedo, Enrique, Bray, Patrick, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Owen, A. (2008) 'Transcriptional Analysis of Putative Folate Transporter Genes in Plasmodium Falciparum'. American Journal of Tropical Medicine and Hygiene, Vol 79, Issue 6 Supp, p. 302.

Sabbani, S., Stocks, Paul A., Ellis, G. L., Davies, Jill, Hedenstrom, E., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and O'Neill, P. M. (2008) 'Piperidine dispiro-1,2,4-trioxane analogues'. Bioorganic & Medicinal Chemistry Letters, Vol 18, Issue 21, pp. 5804-5808.

Janneh, O., Hartkoorn, R. C., Jones, E., Owen, A., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Davey, R., Back, D. J. and Khoo, S. H. (2008) 'Cultured CD4T cells and primary human lymphocytes express hOATPs: intracellular accumulation of saquinavir and lopinavir'. British Journal of Pharmacology, Vol 155, Issue 6, pp. 875-883.

Ochong, Edwin, Bell, David J., Johnson, David, D'Alessandro, U., Mulenga, M., Muangnoicharoen, Sant, Van Geertruyden, J. P., Winstanley, P. A., Bray, Patrick, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Owen, A. (2008) 'Plasmodium falciparum Strains Harboring Dihydrofolate Reductase with the I164L Mutation Are Absent in Malawi and Zambia Even under Antifolate Drug Pressure'. Antimicrobial Agents and Chemotherapy, Vol 52, Issue 11, pp. 3883-3888.

Muchohi, S. N., Kokwaro, G. O., Ogutu, B. R., Edwards, Geoffrey, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Newton, C. R. J. C. (2008) 'Pharmacokinetics and clinical efficacy of midazolam in children with severe malaria and convulsions'. British Journal of Clinical Pharmacology, Vol 66, Issue 4, pp. 529-538.

Fisher, Nicholas, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2008) 'Modelling, cloning and expression of the P.falciparum NADH dehydrogenase'. Biochimica Et Biophysica Acta-Bioenergetics, Vol 1777, S38-S38.

Verissimo, E., Berry, N., Gibbons, P., Cristiano, M. L. S., Rosenthal, P. J., Gut, J., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and O'Neill, P. M. (2008) 'Design and synthesis of novel 2-pyridone peptidomimetic falcipain 2/3 inhibitors'. Bioorganic & Medicinal Chemistry Letters, Vol 18, Issue 14, pp. 4210-4214.

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Fisher, Nicholas, Berry, N., Stocks, Paul A., Meunier, B., Williams, D. P., Bonar-Law, R., Bray, Patrick, Owen, A., O'Neill, P. M. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2008) 'Acridinediones: Selective and potent inhibitors of the malaria parasite mitochondrial bc(1) complex'. Molecular Pharmacology, Vol 73, Issue 5, pp. 1347-1355.

Ellis, G. L., Amewu, R., Sabbani, S., Stocks, Paul A., Shone, Alison, Stanford, D., Gibbons, P., Davies, Jill, Vivas, L., Charnaud, S., Bongard, E., Hall, Charlotte, Rimmer, Karen, Lozanom, S., Jesus, M., Gargallo, D., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and O'Neill, P. M. (2008) 'Two-step synthesis of achiral dispiro-1,2,4,5-tetraoxanes with outstanding antimalarial activity, low toxicity, and high-stability profiles'. Journal of Medicinal Chemistry, Vol 51, Issue 7, pp. 2170-2177.

Johnson, David, Owen, A., Plant, N., Bray, Patrick and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2008) 'Drug-regulated expression of Plasmodium falciparum P-glycoprotein hornologue 1: a putative role for nuclear receptors'. Antimicrobial Agents and Chemotherapy, Vol 52, Issue 4, pp. 1438-1445.

Ellis, Gemma L., Amewu, R., Hall, Charlotte, Rimmer, Karen, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and O'Neill, Paul M. (2008) 'An efficient route into synthetically challenging bridged achiral 1,2,4,5-tetraoxanes with antimalarial activity'. Bioorganic & Medicinal Chemistry Letters, Vol 18, Issue 5, pp. 1720-1724.

Bell, David J., Nyirongo, Suzgo K., Mukaka, Mavuto, Zijlstra, Ed E., Plowe, Christopher V., Molyneux, Malcolm E, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Winstanley, Peter A. (2008) 'Sulfadoxine-pyrimethamine–based combinations for malaria: a randomised blinded trial to compare efficacy, safety and selection of resistance in malawi'. PLoS ONE, Vol 3, Issue 2, e1578.

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Fisher, Nicholas, Berry, N., Stocks, Paul A., Meunier, B., Bray, Patrick, Owen, A., O'Neill, P. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2008) 'Acridinediones: a new class of potent inhibitors selective against the mitochondrial bc1 complex of the malaria parasite Plasmodium falciparum.'. International Journal for Parasitology, Vol 38, Issue Supplement 1, S41-S41.

Fisher, Nicholas, Bray, Patrick, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2007) 'Malaria-parasite mitochondrial dehydrogenases as drug targets: too early to write the obituary'. Trends in Parasitology, Vol 24, Issue 1, pp. 9-10.

Bell, David J., Wootton, D., Mukaka, Mavuto, Montgomery, Jacqui, Kayange, N., Chimpeni, P., Zijlstra, E., Hughes, D. A., Molyneux, Malcolm E, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Winstanley, P. A. and Lalloo, David ORCID: https://orcid.org/0000-0001-7680-2200 (2007) 'The effect of compliance upon clinical effectiveness of chlorproguanil-dapsone (CD) and artemether-lumefantrine (AL) when compared to sulfadoxine-pyrimethamine (SP) for the treatment of uncomplicated falciparum malaria in Malawi - A randomised controlled trial'. American Journal of Tropical Medicine and Hygiene, Vol 77, Issue 5, p. 287.

Hartkoorn, R. C., Khoo, S., Back, D. J., Tjia, J. F., Waitt, C. J., Chaponda, M., Davies, G., Ardrey, Alison, Ashleigh, Samantha and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2007) 'A rapid and sensitive HPLC-MS method for the detection of plasma and cellular rifampicin'. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, Vol 857, Issue 1, pp. 76-82.

Stocks, Paul A., Bray, Patrick, Barton, V. E., Al-Helal, Mohammed, Jones, M., Araujo, N. C., Gibbons, P., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Hughes, Ruth, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Davies, Jill, Amewu, R., Mercer, A. E., Ellis, G. and O'Neill, P. M. (2007) 'Evidence for a common non-heme chelatable-iron-dependent activation mechanism for semisynthetic and synthetic endoperoxide antimalarial drugs'. Angewandte Chemie-International Edition, Vol 46, Issue 33, pp. 6278-6283.

Fisher, Nicholas, Bray, Patrick, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2007) 'The malaria parasite type IINADH : quinone oxidoreductase: an alternative enzyme for an alternative lifestyle'. Trends in Parasitology, Vol 23, Issue 7, pp. 305-310.

Nkhoma, Standwell, Molyneux, Malcolm E and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2007) 'In vitro antimalarial susceptibility profile and PRCRT/PFMDR-1 genotypes of Plasmodium falciparum field isolates from Malawi'. American Journal of Tropical Medicine and Hygiene, Vol 76, Issue 6, pp. 1107-1112.

Hartkoorn, R. C., Chandler, B., Owen, A., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Squire, Bertie ORCID: https://orcid.org/0000-0001-7173-9038, Back, D. J. and Khoo, S. H. (2007) 'Differential drug susceptibility of intracellular and extracellular tuberculosis, and the impact of P-glycoprotein'. Tuberculosis, Vol 87, Issue 3, pp. 248-255.

Nkhoma, Standwell, Molyneux, Malcolm E and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2007) 'Molecular surveillance for drug-resistant Plasmodium falciparum malaria in Malawi'. Acta Tropica, Vol 102, Issue 2, pp. 138-142.

Ochola, Lucy, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Chance, Michael (2007) 'The role of Rab5 proteins in endocytosis in Plasmodium falciparum'. Tropical Medicine & International Health, Vol 12, Issue Suppl., p. 202.

Bell, David J., Nyirongo, S. K., Molyneux, Malcolm E, Winstanley, P. A. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2007) 'Practical HPLC methods for the quantitative determination of common antimalarials in Africa'. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, Vol 847, Issue 2, pp. 231-236.

Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Sevene, E. J. P., Hastings, Ian ORCID: https://orcid.org/0000-0002-1332-742X, Nosten, F. and McGready, R. (2007) 'Antimalarial drugs and pregnancy: safety, pharmacokinetics, and pharmacovigilance'. Lancet Infectious Diseases, Vol 7, Issue 2, pp. 136-144.

Amewu, R., Stachulski, A. V., Berry, N. G., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Davies, Jill, Labat, G., Rossignol, J. F. and O'Neill, P. M. (2006) 'Synthesis of 1,2,4-trioxepanes via application of thiol-olefin Co-oxygenation methodology'. Bioorganic & Medicinal Chemistry Letters, Vol 16, Issue 23, pp. 6124-6130.

Amewu, R., Stachulski, A. V., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Berry, N. G., Bray, Patrick, Davies, Jill, Labat, G., Vivas, L. and O'Neill, P. M. (2006) 'Design and synthesis of orally active dispiro 1,2,4,5-tetraoxanes; synthetic antimalarials with superior activity to artemisinin'. Organic & Biomolecular Chemistry, Vol 4, Issue 24, pp. 4431-4436.

Winstanley, P. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2006) 'Malaria chemotherapy'. Advances in Parasitology, Vol 61, pp. 47-76.

Simpson, Julie A., Agbenyega, Tsiri, Barnes, Karen I., Di Perri, Gianni, Folb, Peter, Gomes, Melba, Krishna, Sanjeev, Krudsood, Srivicha, Looareesuwan, Sornchai, Mansor, Sharif, McIlleron, Helen, Miller, Raymond, Molyneux, Malcolm, Mwenechanya, James, Navaratnam, Visweswaran, Nosten, Francois, Olliaro, Piero, Pang, Lorrin, Ribeiro, Isabela, Tembo, Madalitso, van Vugt, Michele, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Weerasuriya, Kris, Win, Kyaw and White, Nicholas J. (2006) 'Population pharmacokinetics of artesunate and dihydroartemisinin following intra-rectal dosing of artesunate in malaria patients'. PLoS Medicine, Vol 3, Issue 11, -e444.

Bell, David J., Nyirongo, S., Molyneux, Malcolm E, Winstanley, P. A. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2006) 'Population pharmacokinetic modelling of common antimalarial drugs in Malawi'. American Journal of Tropical Medicine and Hygiene, Vol 75, Issue 5 Supp, p. 122.

Bell, David J., Mukaka, Mavuto, Nyirongo, S., Zijlstra, E., Plowe, C. V., Molyneux, Malcolm E, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Winstanley, P. A. (2006) 'A double blinded randomised controlled trial comparing sulfadoxine-pyrimethamine (SP) plus placebo to SP plus chloroquine, SP plus artesunate or SP plus amodiaquine for the treatment of uncomplicated malaria in Malawi'. American Journal of Tropical Medicine and Hygiene, Vol 75, Issue 5 Supp, p. 90.

Richier, E., Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Wein, S., Boudou, F., Bray, Patrick, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Precigout, E., Calas, M., Dubremetz, J. F. and Vial, H. J. (2006) 'Potent antihematozoan activity of novel bisthiazolium drug T16: Evidence for inhibition of phosphatidylcholine metabolism in erythrocytes infected with Babesia and Plasmodium spp.'. Antimicrobial Agents and Chemotherapy, Vol 50, Issue 10, pp. 3381-3388.

Bray, Patrick, Mungthin, M., Hastings, Ian ORCID: https://orcid.org/0000-0002-1332-742X, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Saidu, D. K., Lakshmanan, V., Johnson, David, Hughes, Ruth, Stocks, Paul A., O'Neill, P. M., Fidock, D. A., Warhurst, D. C. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2006) 'PfCRT and the trans-vacuolar proton electrochemical gradient: regulating the access of chloroquine to ferriprotoporphyrin IX'. Molecular Microbiology, Vol 62, Issue 1, pp. 238-251.

O'Neill, P. M., Verissimo, E., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Davies, Jill, Korshin, E. E., Araujo, N., Pugh, M. D., Cristiano, M. L. S., Stocks, Paul A. and Bachi, M. D. (2006) 'Diels-Alder/thiol-olefin co-oxygenation approach to antimalarials incorporating the 2,3-dioxabicyclo[3.3.1]nonane pharmacophore'. Bioorganic & Medicinal Chemistry Letters, Vol 16, Issue 11, pp. 2991-2995.

O'Neill, P. M., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Berry, N. G., Jeyadevan, J. P., Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Asadollaly, E., Park, B. K. and Bray, Patrick (2006) 'A medicinal chemistry perspective on 4-aminoquinoline antimalarial drugs'. Current Topics in Medicinal Chemistry, Vol 6, Issue 5, pp. 479-507.

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Viriyavejakul, P., O'Neill, P. M., Bray, Patrick and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2006) 'Functional characterization and target validation of alternative complex I of Plasmodium falciparum mitochondria'. Antimicrobial Agents and Chemotherapy, Vol 50, Issue 5, pp. 1841-1851.

Simpson, J. A., Hughes, D., Manyando, C., Bojang, K., Aarons, L., Winstanley, P., Edwards, Geoffrey, Watkins, W. A. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2006) 'Population pharmacokinetic and pharmacodynamic modelling of the antimalarial chemotherapy chlorproguanil/dapsone'. British Journal of Clinical Pharmacology, Vol 61, Issue 3, pp. 289-300.

Graham, S. M., Bell, David J., Nyirongo, S., Hartkoorn, R., Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Molyneux, Malcolm E (2006) 'Low levels of pyrazinamide and ethambutol in children with tuberculosis and impact of age, nutritional status, and human immunodeficiency virus infection'. Antimicrobial Agents and Chemotherapy, Vol 50, Issue 2, pp. 407-413.

Newton, P. N., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Angus, B. J., Chierakul, W., Dondorp, A., Ruangveerayuth, R., Silamut, K., Teerapong, P., Suputtamongkol, Y., Looareesuwan, S. and White, N. J. (2006) 'Early treatment failure in severe malaria resulting from abnormally low plasma quinine concentrations'. Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol 100, Issue 2, pp. 184-186.

Janneh, O., Owen, A., Chandler, B., Hartkoorn, R. C., Hart, C. Anthony, Bray, Patrick, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Back, D. J. and Khoo, S. H. (2005) 'Modulation of the intracellular accumulation of saquinavir in peripheral blood mononuclear cells by inhibitors of MRP1, MRP2, P-gp and BCRP'. AIDS, Vol 19, Issue 18, pp. 2097-2102.

Ochola, Lucy, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Chance, Michael (2005) 'Investigating the role of PfRab5 in endocytosis in Plasmodium falciparum [MIM-LO-174325]'. Acta Tropica, Vol 95, S143-S144.

Bray, Patrick, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and O'Neill, P. M (2005) 'Quinolines and artemisinin: Chemistry, biology and history'. Current Topics in Microbiology and Immunology, Vol 295, pp. 3-38.

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Fidock, D. A., Bray, Patrick and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2005) 'Mutations conferring drug resistance in malaria parasite drug transporters Pgh1 and PfCRT do not affect steady-state vacuolar Ca2+ [Letter to the Editor]'. Antimicrobial Agents and Chemotherapy, Vol 49, Issue 11, pp. 4807-4808.

O'Neill, P. M., Rawe, S. L., Borstnik, K., Miller, A., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Bray, Patrick, Davies, Jill, Oh, C. H. and Posner, G. H. (2005) 'Enantiomeric 1,2,4-trioxanes display equivalent in vitro antimalarial activity versus Plasmodium falciparum malaria parasites: Implications for the molecular mechanism of action of the artemisinins'. Chembiochem, Vol 6, Issue 11, pp. 2048-2054.

Hastings, Ian ORCID: https://orcid.org/0000-0002-1332-742X and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2005) 'Coartem (Artemether-Lumefantrine) in Africa: The beginning of the end? [Correspondence]'. Journal of Infectious Disease, Vol 192, Issue 7, pp. 1303-1304.

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, O'Neill, P. M., Bray, Patrick and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2005) 'Current drug development portfolio for antimalarial therapies'. Current Opinion in Pharmacology, Vol 5, Issue 5, pp. 473-478.

Owen, A., Janneh, O., Hartkoorn, R. C., Chandler, B., Bray, Patrick, Martin, P., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Hart, C. Anthony, Khoo, S. H. and Back, D. J. (2005) 'In vitro synergy and enhanced murine brain penetration of saquinavir coadministered with mefloquine'. Journal of Pharmacology and Experimental Therapeutics, Vol 314, Issue 3, pp. 1202-1209.

Chaijaroenkul, W., Bangchang, K. N., Mungthin, M. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2005) 'In vitro antimalarial drug susceptibility in Thai border areas from 1998-2003'. Malaria Journal, Vol 4, p. 37.

Nkhoma, Standwell, Molyneux, Malcolm E and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2005) 'Relative fitness of wild type and mutant pfcrt parasites: An inference from direct in vitro growth competition experiments [MIM-SN-32913]'. Acta Tropica, Vol 95, S143-S143.

Lakshmanan, V., Bray, Patrick, Verdier-Pinard, D., Johnson, David, Horrocks, P., Muhle, R. A., Alakpa, G. E., Hughes, Ruth, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Krogstad, D. J., Sidhu, A. B. S. and Fidock, D. A. (2005) 'A critical role for PfCRT K76T in Plasmodium falciparum verapamil-reversible chloroquine resistance'. Embo Journal, Vol 24, Issue 13, pp. 2294-2305.

Muchohi, S. N., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Preston, L., Newton, C. R. J. C., Edwards, Geoffrey and Kokwaro, G. O. (2005) 'Determination of midazolam and its major metabolite 1 '-hydroxymidazolam by high-performance liquid chromatography-electrospray mass spectrometry in plasma from children'. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, Vol 821, Issue 1, pp. 1-7.

Nzila, Alexis, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Marsh, Kevin, Sims, P. F. G. and Hyde, J. E. (2005) 'Comparative folate metabolism in humans and malaria parasites (part II): activities as yet untargeted or specific to Plasmodium'. Trends in Parasitology, Vol 21, Issue 7, pp. 334-339.

Mandala, W., Maclennan, C., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Molyneux, Malcolm E (2005) 'Immunological mechanisms determining why some African children develop severe malarial anaemia (SMA) and others cerebral malaria (CM) in response to P-falciparum infection [MIM-WM-392094]'. Acta Tropica, Vol 95, S71-S72.

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Bray, Patrick (2005) 'Malaria parasite transporters as a drug-delivery strategy'. Trends in Parasitology, Vol 21, Issue 7, pp. 299-301.

Nzila, Alexis, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Marsh, Kevin, Sims, P. F. G. and Hyde, J. E. (2005) 'Comparative folate metabolism in humans and malaria parasites (part I): pointers for malaria treatment from cancer chemotherapy'. Trends in Parasitology, Vol 21, Issue 6, pp. 292-298.

McGready, R., Stepniewska, K., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Cho, T., Gilveray, G., Looareesuwan, S., White, N. J. and Nosten, F. (2005) 'Pharmacokinetics of dihydroartemisinin following oral artesunate treatment of pregnant women with acute uncomplicated falciparum malaria'. European Journal of Clinical Pharmacology, Vol 62, Issue 5, pp. 367-371.

Makanga, M, Bray, Patrick, Horrocks, P. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2005) 'Towards a proteomic definition of CoArtem action in Plasmodium falciparum malaria'. Proteomics, Vol 5, Issue 7, pp. 1849-1858.

Nzila, Alexis, Ochong, Edwin, Nduati, E., Gilbert, K., Winstanley, P., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Marsh, Kevin (2005) 'Why has the dihydrofolate reductase 164 mutation not consistently been found in Africa yet?'. Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol 99, Issue 5, pp. 341-346.

O'Neill, P. M., Rawe, S. L., Storr, R. C., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Posner, G. H. (2005) 'Lewis acid catalysed rearrangements of unsaturated bicyclic [2.2.n] endoperoxides in the presence of vinyl silanes; access to novel Fenozan BO-7 analogues'. Tetrahedron Letters, Vol 46, Issue 17, pp. 3029-3032.

Bray, Patrick, Martin, R. E., Tilley, L., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Kirk, K. and Fidock, D. A. (2005) 'Defining the role of PfCRT in Plasmodium falciparum chloroquine resistance'. Molecular Microbiology, Vol 56, Issue 2, pp. 323-333.

Gitau, Evelyn, Kokwaro, G, Newton, C and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2005) 'Use of plasma proteomics to discriminate between malaria infected mice from non-infected control mice [MIM-EG-111840]'. Acta Tropica, Vol 95, S46-S47.

Clark, R. L., White, T. E. K., Clode, S. A., Gaunt, I., Winstanley, P. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2004) 'Developmental toxicity of artesunate and an artesunate combination in the rat and rabbit'. Birth Defects Research Part B-Developmental and Reproductive Toxicology, Vol 71, Issue 6, pp. 380-394.

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Pasini, E. M., Hughes, Ruth, De Koning, H. P., Vial, H. J., O'Neill, P. M., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Bray, Patrick (2004) 'Characterization of the choline carrier of Plasmodium falciparum: a route for the selective delivery of novel antimalarial chugs'. Blood, Vol 104, Issue 10, pp. 3372-3377.

Owen, A., Chandler, B., Bray, Patrick, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Hart, C. Anthony, Back, D. J. and Khoo, S. H. (2004) 'Functional correlation of P-glycoprotein expression and genotype with expression of the human immunodeficiency virus type 1 coreceptor CXCR4'. Journal of Virology, Vol 78, Issue 21, pp. 12022-12029.

Johnson, David, Fidock, D. A., Mungthin, M., Lakshmanan, V., Sidhu, A. B. S., Bray, Patrick and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2004) 'Evidence for a central role for PfCRT in conferring Plasmodium falciparum resistance to diverse antimalarial agents'. Molecular Cell, Vol 15, Issue 6, pp. 867-877.

O'Neill, P. M., Mukhtar, A., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Bickley, J. F., Davies, Jill, Bachi, M. D. and Stocks, Paul A. (2004) 'Application of thiol-olefin co-oxygenation methodology to a new synthesis of the 1,2,4-trioxane pharmacophore [Letter]'. Organic Letters, Vol 6, Issue 18, pp. 3035-3038.

O'Neill, Paul M., Stocks, Paul A., Pugh, Matthew D., Araujo, Nuna C., Korshin, Edward E., Bickley, Jamie F., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Bray, Patrick, Pasini, Erica, Davies, Jill, Verissimo, Edite and Bachi, Mario D. (2004) 'Design and synthesis of endoperoxide antimalarial prodrug models'. Angewandte Chemie-International Edition, Vol 43, Issue 32, pp. 4193-4197.

Winstanley, P., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Snow, R. and Breckenridge, A. (2004) 'Therapy of falciparum malaria in Sub-Saharan Africa: from molecule to policy'. Clinical Microbiology Reviews, Vol 17, Issue 3, 612-+.

Alloueche, A., Bailey, Wendi, Barton, S., Bwika, J., Chimpeni, P., Falade, C. O., Fehintola, F. A., Horton, J., Jaffar, S., Kanyok, T., Kremsner, P. G., Kublin, J. G., Lang, T., Missinou, M. A., Mkandala, C., Oduola, A. M. J., Premji, Z., Robertson, L., Sowunmi, A., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Winstanley, P. A. (2004) 'Comparison of chlorproguanil-dapsone with sulfadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in young African children: double-blind randomised controlled trial'. Lancet, Vol 363, Issue 9424, pp. 1843-1848.

Nzila, Alexis, Kokwaro, G., Winstanley, P. A., Marsh, Kevin and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2004) 'Therapeutic potential of folate uptake inhibition in Plasmodium falciparum'. Trends in Parasitology, Vol 20, Issue 3, pp. 109-112.

Jeyadevan, J. P., Bray, Patrick, Chadwick, J., Mercer, A. E., Byrne, A., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Park, B. K., Williams, D. P., Cosstick, R., Davies, Jill, Higson, A. P., Irving, E., Posner, G. H. and O'Neill, P. M. (2004) 'Antimalarial and Antitumor Evaluation of Novel C-10 Non-Acetal Dimers of 10β-(2-Hydroxyethyl)deoxoartemisinin'. Journal of Medicinal Chemistry, Vol 47, Issue 5, pp. 1290-1298.

O'Neill, Paul M., Mukhtar, Amira, Stocks, Paul A., Randle, Laura E., Hindley, Stephen, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Storr, Richard C., Bickley, Jamie F., O'Neil, Ian A., Maggs, James L., Hughes, Ruth, Winstanley, Peter A., Bray, Patrick and Park, B. Kevin (2003) 'Isoquine and related amodiaquine analogues: A new generation of improved 4-aminoquinoline antimalarials'. Journal of Medicinal Chemistry, Vol 46, Issue 23, pp. 4933-4945.

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, O'Neill, Paul M., Nzila, Alexis, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Bray, Patrick (2003) 'Antimalarial chemotherapy: young guns or back to the future?'. Trends in Parasitology, Vol 19, Issue 11, pp. 479-487.

O'Neill, Paul M., Hindley, Stephen, Pugh, Matthew D., Davies, Jill, Bray, Patrick, Park, B. Kevin, Kapu, Dauda S., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Stocks, Paul A. (2003) 'Co(thd)(2): a superior catalyst for aerobic epoxidation and hydroperoxysilylation of unactivated alkenes: application to the synthesis of spiro-1,2,4-trioxanes'. Tetrahedron Letters, Vol 44, Issue 44, pp. 8135-8138.

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Richier, E., Bray, Patrick, Calas, M., Vial, H. and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2003) 'Heme binding contributes to antimalarial activity of bis-quaternary ammoniums'. Antimicrobial Agents and Chemotherapy, Vol 47, Issue 8, pp. 2584-2589.

Eckstein-Ludwig, U., Webb, R. J., van Goethem, I. D. A., East, J. M., Lee, A. G., Kimura, M., O'Neill, P. M., Bray, Patrick, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Krishna, S. (2003) 'Artemisinins target the SERCA of Plasmodium falciparum'. Nature, Vol 424, Issue 6951, pp. 957-961.

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Bray, Patrick, Spiller, D. G., White, M. R. H. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2003) 'The digestive food vacuole of the malaria parasite is a dynamic intracellular Ca2+ store'. Journal of Biological Chemistry, Vol 278, Issue 30, pp. 27910-27915.

Nzila, Alexis, Mberu, Eddy, Bray, Patrick, Kokwaro, Gilbert, Winstanley, Peter, Marsh, Kevin and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2003) 'Chemosensitization of Plasmodium falciparum by probenecid in vitro'. Antimicrobial Agents and Chemotherapy, Vol 47, Issue 7, pp. 2108-2112.

Hempelmann, E., Motta, C. M., Hughes, Ruth, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Bray, Patrick (2003) 'Dangerous midwives and hemoglobin degradation: a response'. Trends in Parasitology, Vol 19, Issue 5, pp. 199-200.

Bray, Patrick, Barrett, Micheal P., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and de Koning, Harry P. (2003) 'Pentamidine uptake and resistance in pathogenic protozoa: past, present and future'. Trends in Parasitology, Vol 19, Issue 5, pp. 232-239.

Saliba, K. J., Allen, R. J. W., Zissis, S., Bray, Patrick, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Kirk, K. (2003) 'Acidification of the malaria parasite's digestive vacuole by a H+-ATPase and a H+-pyrophosphatase'. Journal of Biological Chemistry, Vol 278, Issue 8, pp. 5605-5612.

Hempelmann, E., Motta, C., Hughes, Ruth, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Bray, Patrick (2003) 'Plasmodium falciparum: sacrificing membrane to grow crystals?'. Trends in Parasitology, Vol 19, Issue 1, pp. 23-26.

Hastings, Ian ORCID: https://orcid.org/0000-0002-1332-742X, Bray, Patrick and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2002) 'A requiem for chloroquine'. Science, Vol 298, Issue 5591, pp. 74-75.

Spiller, D. G., Bray, Patrick, Hughes, Ruth, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and White, M. R. H. (2002) 'The pH of the Plasmodium falciparum digestive vacuole: holy grail or dead-end trail?'. Trends in Parasitology, Vol 18, Issue 10, pp. 441-444.

Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Jones, K. (2002) 'Biguanide-atovaquone synergy against Plasmodium falciparum in vitro'. Antimicrobial Agents and Chemotherapy, Vol 46, Issue 8, pp. 2700-2703.

Winstanley, P. A., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Snow, R. W. (2002) 'Clinical status and implications of antimalarial drug resistance'. Microbes and Infection, Vol 4, Issue 2, pp. 157-164.

Bray, Patrick, Saliba, K. J., Davies, Jill, Spiller, D. G., White, M. R. H., Kirk, K. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2002) 'Distribution of acridine orange fluorescence in Plasmodium falciparum-infected erythrocytes and its implications for the evaluation of digestive vacuole pH'. Molecular and Biochemical Parasitology, Vol 119, Issue 2, pp. 301-304.

Bray, Patrick, Saliba, K. J., Davies, Jill, Spiller, D. G., White, M. R. H., Kirk, K. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2002) 'Further comments on the distribution of acridine orange fluorescence in P-falciparum-infected erythrocytes'. Molecular and Biochemical Parasitology, Vol 119, Issue 2, pp. 311-313.

O'Neill, P. M., Pugh, M., Stachulski, A. V., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Davies, Jill and Park, B. K. (2001) 'Optimisation of the allylsilane approach to C-10 deoxo carba analogues of dihydroartemisinin: synthesis and in vitro antimalarial activity of new, metabolically stable C-10 analogues'. Journal of the Chemical Society-Perkin Transactions 1, Issue 20, pp. 2682-2689.

O'Neill, P. M., Pugh, M., Davies, Jill, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Park, B. K. (2001) 'Regioselective Mukaiyama hydroperoxysilylation of 2-alkyl- or 2-aryl-prop-2-en-1-ols: application to a new synthesis of 1,2,4-trioxanes'. Tetrahedron Letters, Vol 42, Issue 27, pp. 4569-4571.

Book Section

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Bray, Patrick and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2017) 'Mechanisms of Antimalarial Drug Resistance' in: Meyers, Douglas L., (ed) Antimicrobial Drug Resistance, Mechanisms of Drug Resistance, Volume 1, Cham, Switzerland, Springer, pp. 629-647.

Fisher, Nicholas, Warman, Ashley, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2010) 'Chapter 17 Type II NADH: Quinone Oxidoreductases of Plasmodium Falciparum and Mycobacterium Tuberculosis. Kinetic and High-Throughput Assays' in: Allison, W. S. and Scheffler, I. E., (eds) Methods in Enzymology, 456, San Diego, Calif., Academic Press, pp. 303-320.

Monograph

Scott, Janet, Sharma, Raman, Meredith, Luke, Dunning, Jake, Moore, Catrin, Sahr, Foday, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Goodfellow, Ian, Horby, Peter and team, RAPIDE-TKM trial (2020) Pharmacokinetics of TKM-130803 in Ebola virus disease in Sierra Leonean subjects. Discussion Paper. Microbiology Society.

Conference or Workshop Item

Johnson, David J., Owen, A., Plant, N. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2008) 'Drug-regulated gene expression of Plasmodium falciparum P-glycoprotein homologue 1: a role for nuclear receptors?' in MAM 2008.

Muchohi, S., Kokwaro, G., Obiero, K., Ogutu, B., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Edwards, Geoffrey and Newton, C. (2005) 'Pharmacokinetics and clinical efficacy of midazolam and lorazepam in Kenyan children with severe malaria and convulsions [MIM-MN-175440]' in 4th MIM Pan-African Malaria Conference, Yaounde, Cameroon, 13-18 November 2005.

Data Collection

Marriott, Amy, Dagley, Jessica, Hegde, S, Steven, Andrew, Fricks, C., DiCosty, U., Mansour, A., Campbell, E. J., Wilson, C. M., Gusovsky, F., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Hong, W. D., O'Neill, P., Moorhead, A., McCall, S., McCall, J. W., Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 and Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476 (2023) Dataset for the article: Dirofilariasis mouse models for heartworm preclinical research. [Data Collection]