Items where Department is "Groups (2002 - 2012) > Molecular & Biochemical Parasitology Group" and Year is 2006

A

Amewu, R., Stachulski, A. V., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Berry, N. G., Bray, Patrick, Davies, Jill, Labat, G., Vivas, L. and O'Neill, P. M. (2006) 'Design and synthesis of orally active dispiro 1,2,4,5-tetraoxanes; synthetic antimalarials with superior activity to artemisinin'. Organic & Biomolecular Chemistry, Vol 4, Issue 24, pp. 4431-4436.

Amewu, R., Stachulski, A. V., Berry, N. G., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Davies, Jill, Labat, G., Rossignol, J. F. and O'Neill, P. M. (2006) 'Synthesis of 1,2,4-trioxepanes via application of thiol-olefin Co-oxygenation methodology'. Bioorganic & Medicinal Chemistry Letters, Vol 16, Issue 23, pp. 6124-6130.

B

Barnish, Guy, Crewe, W. and Theakston, R.David G. (2006) 'Parasitologists lost?'. Trends in Parasitology, Vol 22, Issue 10, pp. 454-455.

Bates, Paul (2006) 'Housekeeping by Leishmania'. Trends in Parasitology, Vol 22, Issue 10, pp. 447-448.

Bell, David J., Nyirongo, S., Molyneux, Malcolm E, Winstanley, P. A. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2006) 'Population pharmacokinetic modelling of common antimalarial drugs in Malawi'. American Journal of Tropical Medicine and Hygiene, Vol 75, Issue 5 Supp, p. 122.

Bell, David J., Mukaka, Mavuto, Nyirongo, S., Zijlstra, E., Plowe, C. V., Molyneux, Malcolm E, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Winstanley, P. A. (2006) 'A double blinded randomised controlled trial comparing sulfadoxine-pyrimethamine (SP) plus placebo to SP plus chloroquine, SP plus artesunate or SP plus amodiaquine for the treatment of uncomplicated malaria in Malawi'. American Journal of Tropical Medicine and Hygiene, Vol 75, Issue 5 Supp, p. 90.

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Viriyavejakul, P., O'Neill, P. M., Bray, Patrick and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2006) 'Functional characterization and target validation of alternative complex I of Plasmodium falciparum mitochondria'. Antimicrobial Agents and Chemotherapy, Vol 50, Issue 5, pp. 1841-1851.

Bray, Patrick, Mungthin, M., Hastings, Ian ORCID: https://orcid.org/0000-0002-1332-742X, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Saidu, D. K., Lakshmanan, V., Johnson, David, Hughes, Ruth, Stocks, Paul A., O'Neill, P. M., Fidock, D. A., Warhurst, D. C. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2006) 'PfCRT and the trans-vacuolar proton electrochemical gradient: regulating the access of chloroquine to ferriprotoporphyrin IX'. Molecular Microbiology, Vol 62, Issue 1, pp. 238-251.

D

Debrah, A. Y., Mand, S., Specht, S., Marfo-Debrekyei, Y., Batsa, L., Pfarr, K., Larbi, J., Lawson, B., Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, Adjei, O. and Hoerauf, A. (2006) 'Doxycycline reduces plasma VEGF-c/sVEGFR-3 and improves pathology in lymphatic filariasis'. PLoS Pathogens, Vol 2, Issue 9, e92.

Dembo, E. G., Phiri, H. T., Montgomery, Jacqui, Molyneux, Malcolm E and Rogerson, S. J. (2006) 'Are Plasmodium falciparum parasites present in peripheral blood genetically the same as those sequestered in the tissues?'. American Journal of Tropical Medicine and Hygiene, Vol 74, Issue 5, pp. 730-732.

Dillon, Rod, Ivens, A. C., Churcher, C., Holroyd, N., Quail, M. A., Rogers, Matthew E., Soares, M. B., Bonaldo, M. F., Casavant, T. L., Lehane, Mike and Bates, Paul (2006) 'Analysis of ESTs from Lutzomyia longipalpis sand flies and their contribution toward understanding the insect-parasite relationship'. Genomics, Vol 88, Issue 6, pp. 831-840.

Diniz, M. R. V., Theakston, R.David G., Crampton, J. M., Cordeiro, M. D., Pimenta, A. M. C., De Lima, M. E. and Diniz, C. R. (2006) 'Functional expression and purification of recombinant Tx1, a sodium channel blocker neurotoxin from the venom of the Brazilian "armed" spider, Phoneutria nigriventer'. Protein Expression and Purification, Vol 50, Issue 1, pp. 18-24.

Dormeyer, M., Adams, Y., Kramer, B., Chakravorty, S., Tse, M.T., Pegoraro, S., Whittaker, Lisa, Lanzer, M. and Craig, Alister ORCID: https://orcid.org/0000-0003-0914-6164 (2006) 'Rational design of anticytoadherence inhibitors for Plasmodium falciparum based on the crystal structure of human intercellular adhesion molecule 1'. Antimicrobial Agents and Chemotherapy, Vol 50, Issue 2, pp. 724-730.

G

Gillette-Ferguson, I., Hise, A. G., Sun, Y., Diaconu, E., McGarry, Helen F., Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 and Pearlman, E. (2006) 'Wolbachia- and Onchocerca volvulus-induced keratitis (River blindness) is dependent on myeloid differentiation factor 88'. Infection and Immunity, Vol 74, Issue 4, pp. 2442-2445.

Graham, S. M., Bell, David J., Nyirongo, S., Hartkoorn, R., Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Molyneux, Malcolm E (2006) 'Low levels of pyrazinamide and ethambutol in children with tuberculosis and impact of age, nutritional status, and human immunodeficiency virus infection'. Antimicrobial Agents and Chemotherapy, Vol 50, Issue 2, pp. 407-413.

Gutierrez, J. M., Theakston, R.David G. and Warrell, D. A. (2006) 'Confronting the neglected problem of snake bite envenoming: The need for a global partnership'. PLoS Medicine, Vol 3, Issue 6, e150.

H

Harris, K. M., Goldberg, B., Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and Lloyd, D. (2006) 'Trichomonas vaginalis and Giardia intestinalis produce nitric oxide and display NO-synthase activity'. Journal of Eukaryotic Microbiology, Vol 53, Issue S1, S182-S183.

Harrison, Robert, Hasson, S.S., Harmsen, M., Laing, Gavin, Conrath, K. and Theakston, R.David G. (2006) 'Neutralisation of venom-induced haemorrhage by IgG from camels and llamas immunised with viper venom and also by endogenous, non-IgG components in camelid sera'. Toxicon, Vol 47, Issue 3, pp. 364-368.

Hastings, Ian ORCID: https://orcid.org/0000-0002-1332-742X (2006) 'Complex dynamics and stability of resistance to antimalarial drugs'. Parasitology, Vol 132, pp. 615-624.

Hastings, Ian ORCID: https://orcid.org/0000-0002-1332-742X (2006) 'Gametocytocidal activity in antimalarial drugs speeds the spread of drug resistance'. Tropical Medicine & International Health, Vol 11, Issue 8, pp. 1206-1217.

Hastings, Ian ORCID: https://orcid.org/0000-0002-1332-742X, Lalloo, David ORCID: https://orcid.org/0000-0001-7680-2200 and Khoo, S. H. (2006) 'No room for complacency on drug resistance in Africa [Correspondence]'. Nature, Vol 444, Issue 7115, p. 31.

Hastings, Ian ORCID: https://orcid.org/0000-0002-1332-742X (2006) 'Population genetics - XYZW as nature's language of love?'. Heredity, Vol 96, Issue 4, pp. 278-279.

Hastings, Ian ORCID: https://orcid.org/0000-0002-1332-742X and Watkins, W. M. (2006) 'Response to Coles: Drug resistance and drug tolerance in parasites [Letters response]'. Trends in Parasitology, Vol 22, Issue 8, p. 349.

Hastings, Ian ORCID: https://orcid.org/0000-0002-1332-742X and Watkins, W. M. (2006) 'Tolerance is the key to understanding antimalarial drug resistance'. Trends in Parasitology, Vol 22, Issue 2, pp. 71-77.

J

Jackson, J. A., Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Kamal, M., Wright, V., Bickle, Q., Else, K. J., Ramsan, M. and Bradley, J. E. (2006) 'Gastrointestinal nematode infection is associated with variation in innate immune responsiveness'. Microbes and Infection, Vol 8, Issue 2, pp. 487-492.

Jariyapan, N., Choochote, W., Jitpakdi, A., Harnnoi, T., Siriyasatein, P., Wilkinson, M. C. and Bates, Paul (2006) 'A glycine- and glutamate-rich protein is female salivary gland-specific and abundant in the malaria vector Anopheles dirus B (Diptera : Culicidae)'. Journal of Medical Entomology, Vol 43, Issue 5, pp. 867-874.

Jenkins, N., Chakravorty, S., Urban, Britta ORCID: https://orcid.org/0000-0002-4197-8393, Kai, O. K., Marsh, K. and Craig, Alister ORCID: https://orcid.org/0000-0003-0914-6164 (2006) 'The effect of Plasmodium falciparum infection on expression of monocyte surface molecules'. Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol 100, Issue 11, pp. 1007-1012.

Juaez, P., Wagstaff, Simon ORCID: https://orcid.org/0000-0003-0577-5537, Oliver, J., Sanz, L., Harrison, Robert and Calvete, J. J. (2006) 'Molecular cloning of disintegrin-like transcript BA-5A from a Bitis arietans venom gland cDNA library: A putative intermediate in the evolution of the long-chain disintegrin bitistatin'. Journal of Molecular Evolution, Vol 63, Issue 1, pp. 142-152.

Juarez, P., Wagstaff, Simon ORCID: https://orcid.org/0000-0003-0577-5537, Sanz, L., Harrison, Robert and Calvete, J. J. (2006) 'Molecular cloning of Echis ocellatus disintegrins reveals non-venom-secreted proteins and a pathway for the evolution of ocellatusin'. Journal of Molecular Evolution, Vol 63, Issue 2, pp. 183-193.

M

Mbuchi, M., Bates, Paul, Ilg, T., Coe, J. E. and Raynes, J. G. (2006) 'C-reactive protein initiates transformation of Leishmania donovani and L-mexicana through binding to lipophosphoglycan'. Molecular and Biochemical Parasitology, Vol 146, Issue 2, pp. 259-264.

N

Newton, P. N., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Angus, B. J., Chierakul, W., Dondorp, A., Ruangveerayuth, R., Silamut, K., Teerapong, P., Suputtamongkol, Y., Looareesuwan, S. and White, N. J. (2006) 'Early treatment failure in severe malaria resulting from abnormally low plasma quinine concentrations'. Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol 100, Issue 2, pp. 184-186.

O

O'Neill, P. M., Verissimo, E., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Davies, Jill, Korshin, E. E., Araujo, N., Pugh, M. D., Cristiano, M. L. S., Stocks, Paul A. and Bachi, M. D. (2006) 'Diels-Alder/thiol-olefin co-oxygenation approach to antimalarials incorporating the 2,3-dioxabicyclo[3.3.1]nonane pharmacophore'. Bioorganic & Medicinal Chemistry Letters, Vol 16, Issue 11, pp. 2991-2995.

Otero, R., Leon, G., Gutierrez, J. M., Rojas, G., Toro, M. F., Barona, J., Rodriguez, V., Diaz, A., Nunez, V., Quintana, J. C., Ayala, S., Mosquera, D., Conrado, L. L., Fernandez, D., Arroyo, Y., Paniagua, C. A., Lopez, M., Ospina, C. E., Alzate, C., Fernandez, J., Meza, J. J., Silva, J. F., Ramirez, P., Fabra, P. E., Ramirez, E., Cordoba, E., Arrieta, A. B., Warrell, D. A. and Theakston, R.David G. (2006) 'Efficacy and safety of two whole IgG polyvalent antivenoms, refined by caprylic acid fractionation with or without beta-propiolactone, in the treatment of Bothrops asper bites in Colombia'. Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol 100, Issue 12, pp. 1173-1182.

R

Richier, E., Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Wein, S., Boudou, F., Bray, Patrick, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Precigout, E., Calas, M., Dubremetz, J. F. and Vial, H. J. (2006) 'Potent antihematozoan activity of novel bisthiazolium drug T16: Evidence for inhibition of phosphatidylcholine metabolism in erythrocytes infected with Babesia and Plasmodium spp.'. Antimicrobial Agents and Chemotherapy, Vol 50, Issue 10, pp. 3381-3388.

S

Senis, Y. A., Kim, P. Y., Fuller, G. L. J., Garcia, A., Prabhakar, S., Wilkinson, M. C., Brittan, H., Zitzmann, N., Wait, R., Warrell, David A., Watson, S. P., Kamiguti, A. S., Theakston, R.David G., Nesheim, M. E. and Laing, Gavin (2006) 'Isolation and characterization of cotiaractivase, a novel low molecular weight prothrombin activator from the venom of Bothrops cotiara'. Biochimica Et Biophysica Acta-Proteins and Proteomics, Vol 1764, Issue 5, pp. 863-871.

Simpson, J. A., Hughes, D., Manyando, C., Bojang, K., Aarons, L., Winstanley, P., Edwards, Geoffrey, Watkins, W. A. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2006) 'Population pharmacokinetic and pharmacodynamic modelling of the antimalarial chemotherapy chlorproguanil/dapsone'. British Journal of Clinical Pharmacology, Vol 61, Issue 3, pp. 289-300.

Simpson, Julie A., Agbenyega, Tsiri, Barnes, Karen I., Di Perri, Gianni, Folb, Peter, Gomes, Melba, Krishna, Sanjeev, Krudsood, Srivicha, Looareesuwan, Sornchai, Mansor, Sharif, McIlleron, Helen, Miller, Raymond, Molyneux, Malcolm, Mwenechanya, James, Navaratnam, Visweswaran, Nosten, Francois, Olliaro, Piero, Pang, Lorrin, Ribeiro, Isabela, Tembo, Madalitso, van Vugt, Michele, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Weerasuriya, Kris, Win, Kyaw and White, Nicholas J. (2006) 'Population pharmacokinetics of artesunate and dihydroartemisinin following intra-rectal dosing of artesunate in malaria patients'. PLoS Medicine, Vol 3, Issue 11, -e444.

Suzuki-Inoue, K., Fuller, G. L. J., Garcia, A., Eble, J. A., Pohlmann, S., Inoue, O., Gartner, T. K., Hughan, S. C., Pearce, A. C., Laing, Gavin, Theakston, R.David G., Schweighoffer, E., Zitzmann, N., Morita, T., Tybulewicz, V. L. J., Ozaki, Y. and Watson, S. P. (2006) 'A novel Syk-dependent mechanism of platelet activation by the C-type lectin receptor CLEC-2'. Blood, Vol 107, Issue 2, pp. 542-549.

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Tilley, L., Davis, T. M. E. and Bray, Patrick (2006) 'Prospects for the treatment of drug-resistant malaria parasites'. Future Microbiology, Vol 1, Issue 1, pp. 127-141.

Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Langley, R. Stuart, Johnston, Kelly, Egerton, Gillian, Wanji, S. and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2006) 'Wolbachia endosymbiotic bacteria of Brugia malayi mediate macrophage tolerance to TLR- and CD40-specific stimuli in a MyD88/TLR2-dependent manner'. Journal of Immunology, Vol 177, Issue 2, pp. 1240-1249.

W

Wagstaff, Simon ORCID: https://orcid.org/0000-0003-0577-5537, Laing, Gavin, Theakston, R.David G, Papaspyridis, Christina and Harrison, Robert (2006) 'Bioinformatics and multiepitope DNA immunization to design rational snake antivenom'. PLoS Medicine, Vol 3, Issue 6, e184.

Wagstaff, Simon ORCID: https://orcid.org/0000-0003-0577-5537 and Harrison, Robert (2006) 'Venom gland EST analysis of the saw-scaled viper, Echis ocellatus, reveals novel alpha(9)beta(1) integrin-binding motifs in venom metalloproteinases and a new group of putative toxins, renin-like aspartic proteases'. Gene, Vol 377, pp. 21-32.

Winstanley, P. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2006) 'Malaria chemotherapy'. Advances in Parasitology, Vol 61, pp. 47-76.

Wort, U. U., Hastings, Ian ORCID: https://orcid.org/0000-0002-1332-742X, Mutabingwa, T. K. and Brabin, Bernard (2006) 'The impact of endemic and epidemic malaria on the risk of stillbirth in two areas of Tanzania with different malaria transmission patterns'. Malaria Journal, Vol 5.

Wu, Yang and Craig, Alister ORCID: https://orcid.org/0000-0003-0914-6164 (2006) 'Comparative proteomic analysis of metabolically labelled proteins from Plasmodium falciparum isolates with different adhesion properties'. Malaria Journal, Vol 5.

Z

Zakeri, S., Lindergard, G., Davies, R. M., Boudin, C., Louis, F. and Hommel, Marcel (2006) 'Identification and typing of Cameroonian isolates of P-malariae using monoclonal antibodies against P-brasilianum'. Acta Tropica, Vol 99, Issue 1, pp. 97-101.