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From evidence to action? Challenges to policy change and programme delivery for malaria in pregnancy

Crawley, J., Hill, Jenny ORCID:, Yartey, J., Robalo, M., Serufilira, A., Ba-Nguz, A., Roman, E., Palmer, A., Asamoa, K. and Steketee, R. (2007) 'From evidence to action? Challenges to policy change and programme delivery for malaria in pregnancy'. Lancet Infectious Diseases, Vol 7, Issue 2, pp. 145-155.

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This paper discusses the factors that influence whether strategies for preventing and treating malaria in pregnancy are successfully translated into national policy and programme implementation, and identifies key operational research issues. Countries require guidance on how to assess the effectiveness of intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine in the context of increasing sulfadoxine-pyrimethamine resistance. At the same time, data on the safety and efficacy of alternatives to sulfadoxine-pyrimethamine for prevention and treatment are urgently needed. Systematic examination of the cultural and operational constraints to delivery and uptake of IPTp with sulfadoxine-pyrimethamine and use of insecticide-treated nets would provide a rational basis for strategies aimed at improving coverage. Standardised methodology must be used to monitor IPTp coverage and to compare different approaches for scaling-up the delivery of insecticide-treated nets to pregnant women. Adequate budgetary provision for the implementation of policy and for operational research to improve programme delivery should be included in national applications to the Global Fund to Fight AIDS, Tuberculosis and Malaria. The provision of clear policy guidance on malaria in pregnancy and its translation into evidence-based guidelines that are made widely available at a country level are central to improving malaria control in this particularly vulnerable group.

Item Type: Article
Uncontrolled Keywords: intermittent preventive treatment placebo-controlled trial routine prophylactic supplementation insecticide-treated bednets randomized controlled-trial sulfadoxine-pyrimethamine western kenya folic-acid plasmodium-falciparum mukono district
Subjects: QV Pharmacology > Anti-Inflammatory Agents. Anti-Infective Agents. Antineoplastic Agents > QV 256 Antimalarials
WA Public Health > Health Problems of Special Population Groups > WA 310 Maternal welfare
WC Communicable Diseases > Tropical and Parasitic Diseases > WC 750 Malaria
WQ Obstetrics > Pregnancy Complications > WQ 256 Infectious diseases
Faculty: Department: Groups (2002 - 2012) > Child & Reproductive Health Group
Digital Object Identifer (DOI):
Related URLs:
Depositing User: Ms Julia Martin
Date Deposited: 24 Sep 2010 12:33
Last Modified: 06 Feb 2018 13:01


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