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Is continuous positive airway pressure (CPAP) a new standard of care for type 1 respiratory failure in COVID-19 patients? A retrospective observational study of a dedicated COVID-19 CPAP service

Nightingale, Rebecca, Nwosu, Nneka, Kutubudin, Farheen, Fletcher, Tom, Lewis, Joseph ORCID: https://orcid.org/0000-0002-3837-5188, Frost, Frederick, Haigh, Kathryn, Robinson, Ryan, Kumar, Ayesha, Jones, Gareth, Brown, Deborah, Abouyannis, Michael ORCID: https://orcid.org/0000-0003-4856-4334, Beadsworth, Mike, Hampshire, Peter, Aston, Stephen, Gautam, Manish and Burhan, Hassan (2020) 'Is continuous positive airway pressure (CPAP) a new standard of care for type 1 respiratory failure in COVID-19 patients? A retrospective observational study of a dedicated COVID-19 CPAP service'. BMJ, Vol 7, e000639.

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Abstract

The aim of this case series is to describe and evaluate our experience of continuous positive airway pressure (CPAP) to treat type 1 respiratory failure in patients with COVID-19. CPAP was delivered in negative pressure rooms in the newly repurposed infectious disease unit. We report a cohort of 24 patients with type 1 respiratory failure and COVID-19 admitted to the Royal Liverpool Hospital between 1 April and 30 April 2020. Overall, our results were positive; we were able to safely administer CPAP outside the walls of a critical care or high dependency unit environment and over half of patients (58%) avoided mechanical ventilation and a total of 19 out of 24 (79%) have survived and been discharged from our care.

Item Type: Article
Subjects: WA Public Health > WA 105 Epidemiology
WC Communicable Diseases > Virus Diseases > Viral Respiratory Tract Infections. Respirovirus Infections > WC 505 Viral respiratory tract infections
WF Respiratory System > WF 100 General works
WF Respiratory System > WF 140 Diseases of the respiratory system (General)
Faculty: Department: Biological Sciences > Department of Tropical Disease Biology
Clinical Sciences & International Health > Clinical Sciences Department
Education
Digital Object Identifer (DOI): https://doi.org/10.1136/bmjresp-2020-000639
Depositing User: Debbie Jenkins
Date Deposited: 14 Jul 2020 13:07
Last Modified: 03 Aug 2020 09:38
URI: https://archive.lstmed.ac.uk/id/eprint/15038

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