Malaria in adolescence: burden of disease, consequences, and opportunities for intervention

Lalloo, David ORCID: https://orcid.org/0000-0001-7680-2200, Olukoya, P. and Olliaro, P. (2006) 'Malaria in adolescence: burden of disease, consequences, and opportunities for intervention'. Lancet Infectious Diseases, Vol 6, Issue 12, pp. 780-793.

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Abstract

The problem of malaria in adolescence has largely been overshadowed by the huge burden of disease in young children. A substantial number of adolescents are at risk from malaria infection, but the burden of disease and consequences of infection in this age-group have rarely been studied. Our understanding of specific risk factors and beneficial interventions for adolescents is also limited. Data show that, from an adolescent viewpoint, malaria is a common cause of clinical illness and a preventable cause of death, even in areas of stable malaria transmission. Younger adolescents might be at a higher risk than older adolescents, because of immunological and hormonal factors. There are limited data about the adverse consequences of malaria in non-pregnant adolescents. However, in pregnant adolescents, the consequences of malaria are of great concern and simple interventions might lead to a substantial benefit. Malaria infection in adolescents is an under-recognised problem, and the prevention, diagnosis, and treatment of malaria should have a high priority within adolescent health programmes.

Item Type:	Article
Uncontrolled Keywords:	papua-new-guinea western amazon region impregnated bed nets intermittent sulfadoxine-pyrimethamine dehydroepiandrosterone-sulfate levels plasmodium-falciparum infections insecticide-treated bednets randomized controlled-trial low seasonal transmission rural malawi
Subjects:	WC Communicable Diseases > Tropical and Parasitic Diseases > WC 770 Therapy WS Pediatrics > By Age Groups > WS 460 Adolescence (General)
Faculty: Department:	Groups (2002 - 2012) > Clinical Group
Digital Object Identifer (DOI):	https://doi.org/10.1016/S1473-3099(06)70655-7
Depositing User:	Ms Julia Martin
Date Deposited:	20 Dec 2010 15:52
Last Modified:	06 Feb 2018 13:02
URI:	https://archive.lstmed.ac.uk/id/eprint/1532

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