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Clinical characteristics and outcomes of confirmed COVID-19 patients in the early months of the pandemic in Tanzania: A multicentre cohort study

Mnyambwa, Nicholaus P., Lubinza, Clara, Ngadaya, Esther, Senkoro, Mbazi, Kimaro, Godfather, Kagaruki, Gibson B., Binagi, Stanley, Malima, Amani, Kazyoba, Paul, Oriyo, Ndekya, Mghamba, Janneth M., Fredrick, Aman, Ramaiya, Kaushik, Zumla, Alimuddin, Jaffar, Shabbar ORCID: https://orcid.org/0000-0002-9615-1588 and Mfinanga, Sayoki (2022) 'Clinical characteristics and outcomes of confirmed COVID-19 patients in the early months of the pandemic in Tanzania: A multicentre cohort study'. IJID Regions. (In Press)

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Abstract

Background
We performed a prospective cohort study of the clinical presentations and management outcomes of laboratory-confirmed COVID-19 patients in the early months of the pandemic at two hospitals in Dar es Salaam, Tanzania.

Methods
Between April 1 - May 31, 2020, laboratory-confirmed COVID-19 patients seen at two tertiary facilities were consecutively enrolled in the study and followed up for 21 days.

Results
We enrolled 121 COVID-19 patients; 112 (92.6%) were admitted while 9 (7.4%) were seen as outpatients. The median (IQR) age of patients was 41 (30-54) years; 72 (59.5%) were male. The medians (IQR) reported days from hospital admission to recovery and death was 10 (6-18) and 5.5 (3-9), respectively. Forty-four (36.4%) patients had at least one underlying condition. Of the 112 admissions, 17 (15.2%) went to ICU, of which 14 (82.3%) died. At the end of follow-up, 93(76.9%) recovered, and 18 (14.9%) died, 7 (5.8%) remained asymptomatic, and 1 (0.8%) was still ill. Overall, 46 (38.3%) patients had at least one underlying condition.

Conclusion
Three-quarters of all COVID-19 patients were aged less than 60 years, reflecting Africa's young population structure. High admission rates to ICU and death rates were observed.

Item Type: Article
Subjects: WA Public Health > Health Problems of Special Population Groups > WA 395 Health in developing countries
WC Communicable Diseases > Virus Diseases > Viral Respiratory Tract Infections. Respirovirus Infections > WC 505 Viral respiratory tract infections
Faculty: Department: Clinical Sciences & International Health > International Public Health Department
Digital Object Identifer (DOI): https://doi.org/10.1016/j.ijregi.2021.12.010
Depositing User: Rachel Dominguez
Date Deposited: 10 Jan 2022 12:23
Last Modified: 10 Jan 2022 12:23
URI: https://archive.lstmed.ac.uk/id/eprint/19764

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