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Clinical characteristics and management of neurocysticercosis patients: a retrospective assessment of case reports from Europe

Stelzle, Dominik, Abraham, Annette, Kaminski, Miriam, Schmidt, Veronika, De Meijere, Robert, Bustos, Javier A, Garcia, Hector Hugo, Sahu, Priyadarshi Soumyaranjan, Bobić, Branko, Cretu, Carmen, Chiodini, Peter, Dermauw, Veronique, Devleesschauwer, Brecht, Dorny, Pierre, Fonseca, Ana, Gabriël, Sarah, Morales, Maria Ángeles Gómez, Laranjo-González, Minerva, Hoerauf, Achim, Hunter, Ewan, Jambou, Ronan, Jurhar-Pavlova, Maja, Reiter-Owona, Ingrid, Sotiraki, Smaragda, Trevisan, Chiara, Vilhena, Manuela, Walker, Naomi ORCID:, Zammarchi, Lorenzo and Winkler, Andrea Sylvia (2022) 'Clinical characteristics and management of neurocysticercosis patients: a retrospective assessment of case reports from Europe'. Journal of Travel Medicine, Vol 30, Issue 1, etaac102.

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Neurocysticercosis (NCC) is a parasitic disease caused by the larval stage of the tapeworm Taenia solium. NCC mainly occurs in Africa, Latin America and South-East Asia and can cause a variety of clinical signs/symptoms. Although it is a rare disease in Europe, it should nonetheless be considered as a differential diagnosis. The aim of this study was to describe clinical characteristics and management of patients with NCC diagnosed and treated in Europe.

We conducted a systematic search of published and unpublished data on patients diagnosed with NCC in Europe (2000–2019) and extracted demographic, clinical and radiological information on each case, if available.

Out of 293 identified NCC cases, 59% of patients presented initially with epileptic seizures (21% focal onset); 52% presented with headache and 54% had other neurological signs/symptoms. The majority of patients had a travel or migration history (76%), mostly from/to Latin America (38%), Africa (32%) or Asia (30%). Treatment varied largely depending on cyst location and number. The outcome was favorable in 90% of the cases.

Management of NCC in Europe varied considerably but often had a good outcome. Travel and migration to and from areas endemic for T. solium will likely result in continued low prevalence of NCC in Europe. Therefore, training and guidance of clinicians is recommended for optimal patient management.

Item Type: Article
Subjects: QX Parasitology > Helminths. Annelida > QX 200 Helminths
WA Public Health > Health Administration and Organization > WA 530 International health administration
WC Communicable Diseases > Tropical and Parasitic Diseases > WC 695 Parasitic diseases (General)
WC Communicable Diseases > Tropical and Parasitic Diseases > WC 698 Parasitic intestinal diseases (General)
Faculty: Department: Clinical Sciences & International Health > Clinical Sciences Department
Digital Object Identifer (DOI):
SWORD Depositor: JISC Pubrouter
Depositing User: JISC Pubrouter
Date Deposited: 24 Nov 2022 16:06
Last Modified: 12 Oct 2023 03:13


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