Tools
Tools
Kengne Fokam, Alvine Christelle, Sumo, Laurentine, Bagayan, Mohamed, Nana-Djeunga, Hugues Clotaire, Kuete, Thomas, Nganjou, Gabriella S. Ondoua, Tchami Mbagnia, Murielle Carole, Djune-Yemeli, Linda, Wondji, Charles 
ORCID: https://orcid.org/0000-0003-0791-3673 and Njiokou, Flobert
(2022)
'Exposition of Intermediate Hosts of Schistosomes to Niclosamide (Bayluscide WP 70) Revealed Significant Variations in Mortality Rates: Implications for Vector Control'. International Journal of Environmental Research and Public Health, Vol 19, Issue 19, e12873.
|
Text
ijerph-19-12873.pdf - Published Version Available under License Creative Commons Attribution. Download (600kB) | Preview |
Abstract
(1) Background: Schistosomiasis remains a public health issue in Cameroon. Snail control using Niclosamide can prevent schistosome transmission. It is safe to determine lethal concentrations for the population. This study aimed at assessing the toxicity of Niclosamide on different developmental stages of snail populations; (2) Methods: Snails were collected, identified, and reared in the laboratory. Egg masses and adult snails were exposed to Niclosamide, at increasing concentrations (0.06, 0.125, 0.25, 0.5, 1 mg/L for egg embryos and 0.06, 0.08, 0.1, 0.12, 0.14, 0.16, 0.18, 0.2 mg/L for adults). After 24 h exposure, egg masses and snails were removed from Niclosamide solutions, washed with source water and observed; (3) Results: Snail susceptibility was species and population dependent. For egg embryos, Biomphalaria pfeifferi was the most susceptible (LC50: 0.1; LC95: 6.3 mg/L) and Bulinus truncatus the least susceptible (LC50: 4.035; LC95: 228.118 mg/L). However, for adults, B. truncatus was the most susceptible (mortality rate: 100%). The LC50 and LC95 for Bi. camerunensis eggs were 0.171 mg/L and 1.102 mg/L, respectively, and were higher than those obtained for adults (0.0357 mg/L and 0.9634 mg/L); (4) Conclusion: These findings will guide the design of vector control strategies targeting these snail species in Cameroon.
| Item Type: | Article |
|---|---|
| Subjects: | QX Parasitology > QX 20 Research (General) QX Parasitology > Helminths. Annelida > QX 355 Schistosoma QX Parasitology > Insects. Other Parasites > QX 600 Insect control. Tick control QX Parasitology > Insects. Other Parasites > QX 650 Insect vectors |
| Faculty: Department: | Biological Sciences > Vector Biology Department |
| Digital Object Identifer (DOI): | https://doi.org/10.3390/ijerph191912873 |
| SWORD Depositor: | JISC Pubrouter |
| Depositing User: | JISC Pubrouter |
| Date Deposited: | 22 Nov 2022 10:54 |
| Last Modified: | 22 Nov 2022 10:54 |
| URI: | https://archive.lstmed.ac.uk/id/eprint/21472 |
Statistics
Actions (login required)
 |
Edit Item |