Tools
Tools
Kadia, Benjamin, Otiti, Mary, Ramsteijn, Anouschka S, Sow, Doudou, Faye, Babacar, Heffernan, Claire, Hall, Lindsay J, Webster, Joanne P, Walker, Alan W and Allen, Stephen 
ORCID: https://orcid.org/0000-0001-6675-249X
(2023)
'Modulating the early-life gut microbiota using pro-, pre-, and synbiotics to improve gut health, child development, and growth'. Nutrition Reviews, Vol 82, Issue 2, pp. 244-247.
|
Text
nuad050.pdf - Published Version Available under License Creative Commons Attribution. Download (450kB) | Preview |
Abstract
In children exposed to poor hygiene and sanitation, invasion of the gut by pathogenic microbes can result in a subclinical enteropathy termed “environmental enteric dysfunction” (EED) that contributes to undernutrition, growth faltering, and impaired organ development. EED may already be present by age 6–12 weeks; therefore, interventions that can be started early in life, and used alongside breastfeeding, are needed to prevent or ameliorate EED. A healthy gut microbiota is critical for intestinal development and repair, nutrient digestion and absorption, and resisting colonization or overgrowth by pathogens. However, its development can be impaired by several environmental factors. Dietary supplementation with pro-, pre-, or synbiotics may be a pragmatic and safe means of building the resilience of the developing gut microbiota against adverse environmental factors, thereby preventing EED.
| Item Type: | Article |
|---|---|
| Subjects: | WS Pediatrics > WS 20 Research (General) WS Pediatrics > Diseases of Children and Adolescents > By System > WS 310 Digestive system WS Pediatrics > By Age Groups > WS 430 Infancy |
| Faculty: Department: | Clinical Sciences & International Health > Clinical Sciences Department |
| Digital Object Identifer (DOI): | https://doi.org/10.1093/nutrit/nuad050 |
| SWORD Depositor: | JISC Pubrouter |
| Depositing User: | JISC Pubrouter |
| Date Deposited: | 22 May 2023 09:58 |
| Last Modified: | 25 Jan 2024 14:40 |
| URI: | https://archive.lstmed.ac.uk/id/eprint/22530 |
Statistics
Actions (login required)
 |
Edit Item |