Low birth weight and fetal anaemia as risk factors for infant morbidity in rural Malawi

Kalanda, Boniface F., Verhoeff, Francine H., le Cessie, S. and Brabin, Bernard (2009) 'Low birth weight and fetal anaemia as risk factors for infant morbidity in rural Malawi'. Malawi medical journal, Vol 21, Issue 2, pp. 69-74.

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Abstract

Low birth weight (LBW) and fetal anaemia (FA) are common in malaria endemic areas. To investigate the incidence of infectious morbidity in infants in rural Malawi in relation to birth weight and fetal anaemia, a cohort of babies was followed for a year on the basis of LBW (<2500) and FA (cord haemoglobin <12.5g/dl). A matched group of normal birth weight (NBW), non-anaemic (NFA) new-borns were enrolled as controls. Morbidity episodes were recorded at 4-weekly intervals and at each extra visit made to a health centre with any illness. Infants in the NBW NFA group experienced an average of 1.15 (95% C.I. 0.99, 1.31), 1.04 (0.89, 1.19), 0.92 (0.73, 1.11) episodes per year of malaria, respiratory infection and diarrhoea respectively. Corresponding values for the LBW FA group were 0.83 (0.5, 1.16), 0.82 (0.5, 1.16) and 0.76 (0.33, 1.19). FA was not associated with a higher incidence of morbidity, but was significantly associated with a shorter time to first illness episode (p=0.014). LBW was not a significant risk factor for higher morbidity incidence. LBW and FA were not significant risk factors for incidence of illness episodes in infants.

Item Type:	Article
Uncontrolled Keywords:	MALARIA CHILDREN GROWTH MORTALITY TRANSMISSION INFECTION DIARRHEA COHORT WOMEN LIFE
Subjects:	WS Pediatrics > Child Care. Nutrition. Physical Examination > WS 115 Nutritional requirements. Nutrition disorders WS Pediatrics > Diseases of Children and Adolescents > By System > WS 300 Hemic and lymphatic system WD Disorders of Systemic, Metabolic or Environmental Origin, etc > Nutrition Disorders > WD 105 Deficiency diseases WS Pediatrics > By Age Groups > WS 421 Diseases of newborn infants WS Pediatrics > By Age Groups > WS 420 Newborn infants. Neonatology WH Hemic and Lymphatic Systems > WH 100 General works
Faculty: Department:	Groups (2002 - 2012) > Child & Reproductive Health Group
Depositing User:	Pauline Anderson
Date Deposited:	12 Mar 2010 15:03
Last Modified:	06 Feb 2018 12:59
URI:	https://archive.lstmed.ac.uk/id/eprint/294

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