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Preventing infection from reusable medical equipment: a systematic review

Sopwith, W., Hart, T. and Garner, Paul ORCID: https://orcid.org/0000-0002-0607-6941 (2002) 'Preventing infection from reusable medical equipment: a systematic review'. BMC Infectious Diseases, Vol 2, Issue 4.

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Abstract

Background: In 2000, the World Health Organization ( WHO) had eight sets of conflicting recommendations for decontaminating medical equipment. We conducted a systematic review of observational studies to assist WHO in reconciling the various guidelines. This paper summarises the methods developed and illustrates the results for three procedures alcohol, bleach and povidone iodine. Methods: We developed a Medline search strategy and applied inclusion criteria specifying the decontamination procedures of interest and an outcome of microbial destruction for a set of marker organisms. We developed protocols to assess the quality of studies and categorised them according to the reliability of the methods used. Through an iterative process we identified best practice for the decontamination methods and key additional factors required to ensure their effectiveness. We identified 88 published papers for inclusion, describing 135 separate studies of decontamination. Results: For disinfection with alcohol, best practice was identified from 23 studies as an exposure to 70-80% ethanol or isopropanol for at least 5 minutes. Bleach was effective for sterilization at a concentration of 5000 ppm for 5 minutes and for disinfection at 1000 ppm for 10 minutes ( 33 studies). Povidone iodine was only partially effective for disinfection at a concentration of 1% for 15 minutes ( 15 studies). Conclusions: Our findings provide an evidence base for WHO guidelines on decontaminating medical equipment. The results support the recommended use of bleach and show that alcohol could be used more widely than current guidelines suggest, provided best practice is followed. The effectiveness of povidone iodine is uncertain.

Item Type: Article
Subjects: WC Communicable Diseases > Infection. Bacterial Infections > General Infection > WC 195 Infection. Cross infection. Laboratory infection
WX Hospitals and Other Health Facilities > Hospital Administration > WX 167 Cross infection prevention and control
Faculty: Department: Groups (2002 - 2012) > International Health Group
Digital Object Identifer (DOI): https://doi.org/10.1186/1471-2334-2-4
Depositing User: Martin Chapman
Date Deposited: 07 Jan 2014 10:56
Last Modified: 06 Sep 2019 10:14
URI: https://archive.lstmed.ac.uk/id/eprint/2986

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