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Syphilis screening practices in blood transfusion facilities in Ghana

Sarkodie, Francis, Hassall, Oliver, Owusu-Dabo, Ellis, Owusu-Ofori, Shirley, Bates, Imelda ORCID:, Bygbjerg, Ib C, Ansah, Justina Kordai and Ullum, Henrik (2016) 'Syphilis screening practices in blood transfusion facilities in Ghana'. International Journal of Infectious Diseases, Vol 43, pp. 90-94.

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The primary objective of this study was to compare laboratory practices for screening blood donors for syphilis at blood transfusion facilities in Ghana with the recommendations of the World Health Organization and the National Blood Service, Ghana (NBSG). The prevalence of syphilis antibodies in blood donors in Ghana was also estimated.

Over an 11-month period, from February 2014 to January 2015, a semi-structured questionnaire was administered to 122 laboratory technical heads out of a total of 149 transfusion facilities in Ghana. The response rate was 81.9%.

A total of 58 (48%) transfusion facilities tested donors for syphilis, with an estimated 3.7% seroprevalence (95% confidence interval 3.6–3.8%). A total of 62 782 out of 91 386 (68.7%) donations were tested with assays that are not recommended. The estimated syphilis seroprevalence in voluntary donations was 2.9%, compared to 4.0% in family donations (p = 0.001). Only 6.9% of the health facilities were using standard operating procedures (SOPs).

Despite international and national recommendations, more than half of the studied health facilities that provide blood transfusions in Ghana are not screening blood donations for syphilis. These data show a considerable mismatch between recommendations and practice, with serious consequences for blood safety and public health.

Item Type: Article
Subjects: WB Practice of Medicine > Therapeutics > WB 356 Blood transfusion
WC Communicable Diseases > Sexually Transmitted Diseases > WC 160 Syphilis
WH Hemic and Lymphatic Systems > Hematologic Diseases. Immunologic Factors. Blood Banks > WH 460 Blood bank procedures
Faculty: Department: Clinical Sciences & International Health > International Public Health Department
Digital Object Identifer (DOI):
Depositing User: Jessica Jones
Date Deposited: 19 Feb 2016 15:01
Last Modified: 22 Oct 2019 08:23


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