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Runge-Ranzinger, Silvia, Kroeger, Axel, Olliaro, Piero, McCall, Philip 
ORCID: https://orcid.org/0000-0002-0007-3985, Sánchez Tejeda, Gustavo, Lloyd, Linda S, Hakim, Lokman, Bowman, Leigh, Horstick, Olaf and Coelho, Giovanini
(2016)
'Dengue Contingency Planning: From Research to Policy and Practice'. PLoS Neglected Tropical Diseases, Vol 10, Issue 9, e0004916.
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PLoS_Neg_Trop_10_9_e0004916_Dengue Contingency Planning.PDF - Published Version Available under License Creative Commons Attribution. Download (2MB) | Preview |
Abstract
Background
Dengue is an increasingly incident disease across many parts of the world. In response, an evidence-based handbook to translate research into policy and practice was developed. This handbook facilitates contingency planning as well as the development and use of early warning and response systems for dengue fever epidemics, by identifying decision-making processes that contribute to the success or failure of dengue surveillance, as well as triggers that initiate effective responses to incipient outbreaks.
Methodology/Principal findings
Available evidence was evaluated using a step-wise process that included systematic literature reviews, policymaker and stakeholder interviews, a study to assess dengue contingency planning and outbreak management in 10 countries, and a retrospective logistic regression analysis to identify alarm signals for an outbreak warning system using datasets from five dengue endemic countries. Best practices for managing a dengue outbreak are provided for key elements of a dengue contingency plan including timely contingency planning, the importance of a detailed, context-specific dengue contingency plan that clearly distinguishes between routine and outbreak interventions, surveillance systems for outbreak preparedness, outbreak definitions, alert algorithms, managerial capacity, vector control capacity, and clinical management of large caseloads. Additionally, a computer-assisted early warning system, which enables countries to identify and respond to context-specific variables that predict forthcoming dengue outbreaks, has been developed.
Conclusions/Significance
Most countries do not have comprehensive, detailed contingency plans for dengue outbreaks. Countries tend to rely on intensified vector control as their outbreak response, with minimal focus on integrated management of clinical care, epidemiological, laboratory and vector surveillance, and risk communication. The Technical Handbook for Surveillance, Dengue Outbreak Prediction/ Detection and Outbreak Response seeks to provide countries with evidence-based best practices to justify the declaration of an outbreak and the mobilization of the resources required to implement an effective dengue contingency plan.
| Item Type: | Article |
|---|---|
| Subjects: | WA Public Health > WA 105 Epidemiology WA Public Health > Health Administration and Organization > WA 530 International health administration WC Communicable Diseases > Virus Diseases > Infectious Mononucleosis. Arbovirus Infections > WC 528 Dengue |
| Faculty: Department: | Clinical Sciences & International Health > International Public Health Department Biological Sciences > Vector Biology Department |
| Digital Object Identifer (DOI): | https://doi.org/10.1371/journal.pntd.0004916 |
| SWORD Depositor: | JISC Pubrouter |
| Depositing User: | JISC Pubrouter |
| Date Deposited: | 04 Oct 2016 09:47 |
| Last Modified: | 06 Feb 2018 13:13 |
| URI: | https://archive.lstmed.ac.uk/id/eprint/6228 |
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