Short-Term changes in Anemia and Malaria Parasite Prevalence in Children under 5 years during One Year of Repeated Cross-Sectional Surveys in Rural Malawi

Kabaghe, Alinune N., Chipeta, Michael, Terlouw, Anja ORCID: https://orcid.org/0000-0001-5327-8995, McCann, Robert S., van Vugt, Michele, Grobusch, Martin P., Takken, Willem and Phiri, Kamija S (2017) 'Short-Term changes in Anemia and Malaria Parasite Prevalence in Children under 5 years during One Year of Repeated Cross-Sectional Surveys in Rural Malawi'. American Journal of Tropical Medicine and Hygiene, Vol 97, Issue 5, pp. 1568-1575.

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Abstract

In stable transmission areas, malaria is the leading cause of anemia in children. Anemia in children is proposed as an added sensitive indicator for community changes in malaria prevalence. We report short-term temporal variations of malaria and anemia prevalence in rural Malawian children. Data from five repeated cross-sectional surveys conducted over 1 year in rural communities in Chikwawa District, Malawi, were analysed. Different households were sampled per survey; all children, 6-59 months, in sampled household were tested for malaria parasitemia and haemoglobin levels using malaria rapid diagnostic tests (mRDT) and Hemocue 301, respectively. Malaria symptoms, recent treatment (2 weeks) for malaria, anthropometric measurements, and sociodemographic details were recorded. In total, 894 children were included from 1377 households. The prevalences of mRDT positive and anemia (Hb<11g/dL) were 33.8% and 58.7%, respectively. Temporal trends in anemia and parasite prevalence varied differently. Overall, unadjusted and adjusted relative risks of anemia in mRDT-positive children were 1.31 (95% CI: 1.09-1.57) and 1.36 (1.13-1.63), respectively. Changes in anemia prevalence differed with short-term changes in malaria prevalence, although malaria is an important factor in anemia.

Item Type:	Article
Subjects:	QS Anatomy > QS 4 General works. Classify here works on regional anatomy WA Public Health > WA 30 Socioeconomic factors in public health (General) WA Public Health > Health Problems of Special Population Groups > WA 395 Health in developing countries WA Public Health > Statistics. Surveys > WA 900 Public health statistics WA Public Health > Statistics. Surveys > WA 950 Theory or methods of medical statistics. Epidemiologic methods WH Hemic and Lymphatic Systems > Hematologic Diseases. Immunologic Factors. Blood Banks > WH 155 Anemia WS Pediatrics > Diseases of Children and Adolescents > General Diseases > WS 200 General works
Faculty: Department:	Clinical Sciences & International Health > Clinical Sciences Department
Digital Object Identifer (DOI):	https://doi.org/10.4269/ajtmh.17-0335
Depositing User:	Stacy Murtagh
Date Deposited:	31 Aug 2017 09:05
Last Modified:	13 Sep 2019 13:10
URI:	https://archive.lstmed.ac.uk/id/eprint/7398

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