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T*
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[(viewers.)-503.8(Articles)-507.5(were)-502.9(assessed)-506.9(for)-504.3(inclusion)-500.8(by)-503.3(one)-499.8(re-)]TJ
T*
[(viewer.)-335.9(A)-336(subsample)-341.5(of)-330.5(titles)-336.4(was)-339.2(then)-334(selected)-341.8(at)-331.8(random,)]TJ
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[(and)-229.1(the)-229.2(decision)-230.1(to)-227(include)-229.2(or)-226.8(exclude)-230.2(each)-226.8(article)-236.2(was)-224(cross-)]TJ
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[(validated)-284.5(by)-278.7(two)-280.8(reviewers.)]TJ
1.0137 -1.1116 TD
[(If)-318.9(an)-314.4(article)-322.6(describing)-318.6(a)-319(given)-317.8(outbreak)-322.3(provided)-321.1(formal)]TJ
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[(evidence)-220.9(of)-215.3(laboratory)-220.9(conrmation)-217.3(of)-215.3(NoV)-218.2(infection)-219.9(in)-215.4(both)]TJ
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[(human)-428.4(cases)-423.3(and)-430.7(foodstuffs,)-423(that)-426.3(outbreak)-425.9(was)-425.6(classed)-431.4(as)]TJ
T*
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26.5177 67.9242 TD
[(If)-226.8(a)-232.7(report)-226.7(describing)-232.2(a)-226.9(given)-231.4(outbreak)-230.1(included)-230.3(laboratory)]TJ
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[(conrmatio)-8.9(n)-289.1(o)0(f)-290.1(infection)-294.8(in)-290.3(both)-286.8(patrons)-291(and)-292.5(food)-292.4(handlers,)]TJ
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[(with)-247.4(either)-251.1(the)-246.5(same)-243.9(strain)-249.7(being)-248.7(identied)-248.6(in)-244.2(either)-245.3(handlers)]TJ
T*
[(or)-249.8(cases,)-248.2(or)-244.1(in)-244.2(handlers)-247.2(and)-246.4(in)-250(foods)-241.4(consumed)-248.3(by)-249.9(cases,)-248.2(that)]TJ
T*
[(outbreak)-523.9(was)-517.8(classied)-525.7(as)-515.8(denitively)-521.7(attributed)-520.7(to)-520.7(food)]TJ
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[(handlers.)-394.6(Genotypes)-393.2(of)-393.8(strains)-394.6(found)-391.4(in)-388.2(food)-390.3(handlers)-396.9(and)]TJ
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[(foods)-281.7(were)-284(reported)-281.9(where)-285.1(possible.)]TJ
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[(Data)-337.7(collection)]TJ
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[(Data)-434(from)-426(each)-434.1(article)-432(were)-428(collated)-433.1(into)-425.1(a)-428.5(single)-434.1(data)]TJ
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[(abstra)-8.8(ction)-531.1(sheet)-537.7(\(Supplementary)-538.6(Data)-537.6(S2\).)-536.4(In)-532.1(brief,)-534.3(for)]TJ
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[(studie)-7.8(s)-467.4(o)0(f)-468.7(foodborne)-466(infection,)-476.8(information)-469.9(was)-471.7(collected)]TJ
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[(about)-404.2(foods)-402.7(implicated)-407.9(and)-396.1(number)-406.4(of)-399.6(samples)-402.7(taken.)-403.1(For)]TJ
T*
[(food-h)-6.5(andler)-308.5(studies,)-305.9(information)-314.3(was)-304.6(collected)-314.5(on)-307.5(settings,)]TJ
0 -1.1174 TD
[(foods)-443(handled,)-439.8(and,)-439.9(where)-440.7(possible,)-445.3(number)-435.2(and)-442.2(types)-438.6(of)]TJ
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[(sampl)-7.8(es)-279.6(tested)-279.7(from)-282(food)-280.8(handlers)-287.5(and)-280.9(NoV)-281.5(genotypes.)]TJ
/F9 1 Tf
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[(tween)-198.9(articles)-196.8(in)-192.4(terms)-192.1(of)-192.2(study)-195.5(design,)-189.7(timeframes,)-199(and)-194.5(study)]TJ
T*
[(populations)-554.9(prohibited)-553.9(a)-555.2(formal)-556.2(statistical)-551.6(meta-analysis;)]TJ
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[(howev)-7.5(er,)-496.3(descriptive)-499.6(statistics)-503(\(proportions,)-500.4(medians,)-504.2(and)]TJ
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[(interquartile)-283.3(ranges\))-274.7(were)-278.3(calculated)-276.4(for)-273.9(data)-277.6(extracted)-279.7(from)]TJ
T*
[(articles)-288.9(that)-282.3(met)-282.3(the)-281.1(inclusion)-282(criteria.)]TJ
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(Results)Tj
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[(Literature)-340.2(search)]TJ
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[(A)-272.7(total)-272(of)-267.1(9880)-269.4(articles)-271.6(were)-272.5(originally)-271.9(retrieved)-278.5(from)-270.5(the)]TJ
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[(search)-286.3(strategies)-290.9(\(Supplementary)-285.1(Table)-285.6(S1\).)-283(A)-284.2(total)-283.5(of)-284.4(6859)]TJ
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[(article)-483.8(duplicates)-481.2(were)-479.9(removed,)-481.2(leaving)-482.6(3021)-476.7(articles)-479(to)]TJ
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[(screen.)-312.8(Of)-302.5(these)-307.3(2933)-303.9(\(97%\))-306(did)-302.9(not)-302.9(meet)-307.6(the)-304.1(inclusion)-310.8(cri-)]TJ
T*
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[(they)-466.5(concentrated)-468.5(on)-463(diagnostics,)-461.4(articial)-468.7(contamination,)]TJ
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[(efcacy)-288.6(of)-290.1(decontamination,)-285.6(etiology,)-290.3(and)-280.9(outbreak)-287.7(control;)]TJ
T*
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[(information)-239.5(found)-230.1(in)-238.5(other)-231.4(articles;)-238.3(and)-234.9(2)-231.5(references)-241.2(\(0.06%\))]TJ
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[(-denite)-477.7(foodborne)-477.6(outbreaks)-478.7(document)-473.3(36)-474.5(separate)-479.9(inci-)]TJ
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[(dents.)-280.7(The)-282.1(citations)-277.5(are)-282.1(included)-276.3(in)-278.8(Supplementary)-284.1(Data)-278.4(S3.)]TJ
1.0137 -1.1116 TD
[(Out)13(bre)12.8(aks)-263.5(tha)12.7(t)-277.7(met)-265(the)-263.8(de)13(nit)13.7(ion)-268.4(for)-262.4(de)13(nit)13.7(e)-278.7(foo)19.8(d-h)14(and)12.8(ler)]TJ
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T*
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[(eac)10.5(h)-214.2(out)13.8(bre)12.8(ak,)-202.6(hen)12.8(ce)-211.9(it)-209.8(is)-203.7(inc)12.7(lud)13.9(ed)-210.7(as)-210.5(one)-206.1(ag)13.9(gre)12.9(gat)12.7(e)-215.4(out)13.9(bre)12.8(ak.)]TJ
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[(NoV)-340.3(foodborne)-333.8(outbreaks)]TJ
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[(NoV)-298.8(foodborne)-299(outbreaks)-300.1(were)-301.3(reported)-299.2(from)-299.3(around)-301.5(the)]TJ
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[(globe;)-226.9(however,)-221.7(the)-223.5(largest)-223.2(proportion)-224.3(\(57%\))-219.6(was)-224(reported)-224.3(in)]TJ
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[(people)-314.3(providing)-309.6(samples)-310.5(for)-308.5(testing)-308.6(was)-310.4(betwe)-8.8(en)-308.6(1)-306.4(\(David)]TJ
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T*
[(et)-193.6(al.)]TJ
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[(,)-187.7(2007;)-190(Fitzgerald)]TJ
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[(,)-193.5(2014\))-189.8(and)-188.8(42)-192.3(\(Le)-189.9(Guyader)]TJ
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[(2006\))-281.9(\(median)]TJ
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[(8)-277.6(people\).)-284.3(The)-282.1(median)-286.8(\(interquartile)-284.4(range\))]TJ
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[(for)-371.9(the)-367.5(proportion)-368.3(of)-365(NoV-positive)-373.4(samples)-368.1(was)-368(79%)-373(\(52)]TJ
T*
[(100%\),)-361.3(with)-362.6(the)-361.7(median)-361.6(number)-360.3(of)-359.3(positive)-361.5(samples)-362.3(being)]TJ
T*
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[(124\))-506.6(\(Prato)]TJ
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[(,)-504.5(2004;)-506.7(David)]TJ
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(Nenonen)Tj
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[(et)-216.6(al.)]TJ
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[(,)-216.5(2009;)-213(Institute)-218.7(of)-215.3(Environmental)-221(Science)-213.9(and)]TJ
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[(Research,)-242.3(2011;)-230.3(Centers)-241.4(for)-233.6(Disease)-236.4(Control)-233.6(and)-234.8(Prevention,)]TJ
T*
[(2012;)-282.1(Fitzgerald)]TJ
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[(,)-279.9(2014;)-282.1(Muller)]TJ
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[(et)-280(al.)]TJ
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T*
[(me)-15.8(n)9.6(t).3(ary)-327.9(Table)-15.8(s)-312.7(S).5(2)-327.9(a)-.8(nd)-327.9(S3)-327.9(indic)-15.8(a)8.5(te)-323.3(t)-15.8(h)10.7(at)-322.3(a)-329.1(gre)-15.8(a)8.5(t).3(er)-327.9(diver)-15.8(s)11(ity)-327.9(of)]TJ
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[(g)-15.8(e)9.6(notyp)-15.8(e)9.6(s)-362.3(wa)-15.8(s)-353(r).4(eco)-15.8(v)10.8(e)-.8(red)-368.2(from)-363.7(p)-15.8(e)9.6(ople)-369.4(a)-.8(ffect)-15.8(e)9.5(d)-362.5(by)-368.2(the)-363.6(i).3(mp)-15.8(l)10.7(i).3(-)]TJ
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