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Yield of SmearMicroscopy and Radiological Findings of Male and Female Patients with Tuberculosis in Abuja, Nigeria

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Lawson, Lovett, Yassin, Mohammed A., Onuoha, Alex N, Ramsay, Andrew, Anderson de Cuevas, Rachel, Theobald, Sally ORCID: https://orcid.org/0000-0002-9053-211X, Davies, Peter and Cuevas, Luis ORCID: https://orcid.org/0000-0002-6581-0587 (2010) 'Yield of SmearMicroscopy and Radiological Findings of Male and Female Patients with Tuberculosis in Abuja, Nigeria'. Tuberculosis Research and Treatment, Vol 2010.

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Abstract

Objective. To describe the yield of smear-microscopy and radiological findings by male and female patients with symptoms of tuberculosis in Abuja, Nigeria. Methods. Patients ≥15 years old with cough for >3 weeks submitted 3 sputum samples for smear microscopy. One specimen was cultured using MGIT-960. All patients had lung X-rays and screened for HIV. Results. were more likely to be smear-positive than females (262/774 [34%] and 137/547 [25%], P<.01), but similar proportions of males and females were culture-positive (437/691 [63%] and 294/495 [59%], P=.09). 317/626 (50.6%) males and 249/419 (59.4%) females were HIV-positive (P<.005). Among culture-positives patients, HIV-infected males were less likely to have positive smears than HIV-negative males (49.2% versus 66%, P=.001). Among females, smear positivity did not vary with HIV (46.4% for HIV-positive and 52.9% for HIV-negative, P=.38). Of 274 culture-confirmed TB cases, 226 (82.5%) had cavities, and 271 (99%) had ≥1 lung areas affected. HIV-positive males were more likely to have lung cavities than HIV-positive females (85% versus 69%, P<.04) and to have ≥3 lung areas affected (P=.03). Conclusion. Differences in the yield of smear-microscopy, culture and X-rays on presentation are due to several factors including HIV coinfection and gender.

Item Type: Article
Uncontrolled Keywords: Tuberculosis, Smear Microscopy, Abuja, Nigeria
Subjects: WA Public Health > WA 100 General works
WF Respiratory System > Tuberculosis > WF 200 Tuberculosis (General)
Faculty: Department: Groups (2002 - 2012) > Child & Reproductive Health Group
Groups (2002 - 2012) > International Health Group
Digital Object Identifer (DOI): https://doi.org/10.1155/2010/241659
Depositing User: q Moody
Date Deposited: 04 Jan 2011 16:54
Last Modified: 06 Feb 2018 13:02
URI: http://archive.lstmed.ac.uk/id/eprint/1716

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