Yield of SmearMicroscopy and Radiological Findings of Male and Female Patients with Tuberculosis in Abuja, Nigeria

Lawson, Lovett, Yassin, Mohammed A., Onuoha, Alex N, Ramsay, Andrew, Anderson de Cuevas, Rachel, Theobald, Sally ORCID: https://orcid.org/0000-0002-9053-211X, Davies, Peter and Cuevas, Luis ORCID: https://orcid.org/0000-0002-6581-0587 (2010) 'Yield of SmearMicroscopy and Radiological Findings of Male and Female Patients with Tuberculosis in Abuja, Nigeria'. Tuberculosis Research and Treatment, Vol 2010.

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Abstract

Objective. To describe the yield of smear-microscopy and radiological findings by male and female patients with symptoms of tuberculosis in Abuja, Nigeria. Methods. Patients ≥15 years old with cough for >3 weeks submitted 3 sputum samples for smear microscopy. One specimen was cultured using MGIT-960. All patients had lung X-rays and screened for HIV. Results. were more likely to be smear-positive than females (262/774 [34%] and 137/547 [25%], P<.01), but similar proportions of males and females were culture-positive (437/691 [63%] and 294/495 [59%], P=.09). 317/626 (50.6%) males and 249/419 (59.4%) females were HIV-positive (P<.005). Among culture-positives patients, HIV-infected males were less likely to have positive smears than HIV-negative males (49.2% versus 66%, P=.001). Among females, smear positivity did not vary with HIV (46.4% for HIV-positive and 52.9% for HIV-negative, P=.38). Of 274 culture-confirmed TB cases, 226 (82.5%) had cavities, and 271 (99%) had ≥1 lung areas affected. HIV-positive males were more likely to have lung cavities than HIV-positive females (85% versus 69%, P<.04) and to have ≥3 lung areas affected (P=.03). Conclusion. Differences in the yield of smear-microscopy, culture and X-rays on presentation are due to several factors including HIV coinfection and gender.

Item Type:	Article
Uncontrolled Keywords:	Tuberculosis, Smear Microscopy, Abuja, Nigeria
Subjects:	WA Public Health > WA 100 General works WF Respiratory System > Tuberculosis > WF 200 Tuberculosis (General)
Faculty: Department:	Groups (2002 - 2012) > Child & Reproductive Health Group Groups (2002 - 2012) > International Health Group
Digital Object Identifer (DOI):	https://doi.org/10.1155/2010/241659
Depositing User:	Faye Moody
Date Deposited:	04 Jan 2011 16:54
Last Modified:	17 Jul 2020 10:58
URI:	https://archive.lstmed.ac.uk/id/eprint/1716

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